ATM and related protein kinases: safeguarding genome integrity | Nature Reviews Cancer | 2003 | 2.1K |
Requirement of the MRN complex for ATM activation by DNA damage | EMBO Journal | 2003 | 780 |
Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 485 |
The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons | Science | 2003 | 353 |
Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 243 |
Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells | Genome Research | 2003 | 242 |
Prevalence and evolutionary origins of the del(GJB6-D13S1830) mutation in the DFNB1 locus in hearing-impaired subjects: a multicenter study | American Journal of Human Genetics | 2003 | 236 |
Taking geometry to its edge: fast unbound rigid (and hinge-bent) docking | Proteins: Structure, Function and Bioinformatics | 2003 | 217 |
Intronic sequences flanking alternatively spliced exons are conserved between human and mouse | Genome Research | 2003 | 203 |
Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice | American Journal of Physiology - Endocrinology and Metabolism | 2003 | 134 |
Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3 | Journal of Pharmacology and Experimental Therapeutics | 2003 | 130 |
Exposure of human peripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chromosomal instability | Bioelectromagnetics | 2003 | 121 |
The sequence dependence of fiber organization. A comparative molecular dynamics study of the islet amyloid polypeptide segments 22-27 and 22-29 | Journal of Molecular Biology | 2003 | 88 |
Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine | Trends in Pharmacological Sciences | 2003 | 85 |
Mechanism of low-density lipoprotein oxidation by hemoglobin-derived iron | Biochemistry | 2003 | 72 |
A novel algorithm for computational identification of contaminated EST libraries | Nucleic Acids Research | 2003 | 65 |
SiteLight: binding-site prediction using phage display libraries | Protein Science | 2003 | 54 |
The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity | Molecular and Cellular Biology | 2003 | 50 |
New organs from our own tissues: liver-to-pancreas transdifferentiation | Trends in Endocrinology and Metabolism | 2003 | 42 |
ATM: ready, set, go | Cell Cycle | 2003 | 41 |
Reducing the computational complexity of protein folding via fragment folding and assembly | Protein Science | 2003 | 41 |
Challenges and opportunities with glycogen synthase kinase-3 inhibitors for insulin resistance and Type 2 diabetes treatment | Expert Opinion on Investigational Drugs | 2003 | 40 |
Temperature range of thermodynamic stability for the native state of reversible two-state proteins | Biochemistry | 2003 | 39 |
Triggering loops and enzyme function: identification of loops that trigger and modulate movements | Journal of Molecular Biology | 2003 | 38 |
The U1 snRNP base pairs with the 5' splice site within a penta-snRNP complex | Molecular and Cellular Biology | 2003 | 37 |