ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids | Nucleic Acids Research | 2010 | 1.3K |
Alternative splicing and evolution: diversification, exon definition and function | Nature Reviews Genetics | 2010 | 705 |
The genome-wide structure of the Jewish people | Nature | 2010 | 295 |
Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82 | American Journal of Human Genetics | 2010 | 223 |
Structure determination and improved model of plant photosystem I | Journal of Biological Chemistry | 2010 | 219 |
ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage | Science Signaling | 2010 | 212 |
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB | Nature Structural and Molecular Biology | 2010 | 181 |
Dynamic single-cell imaging of direct reprogramming reveals an early specifying event | Nature Biotechnology | 2010 | 178 |
Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 176 |
Expander: from expression microarrays to networks and functions | Nature Protocols | 2010 | 165 |
Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response | Cell Cycle | 2010 | 147 |
Specific high-affinity binding of thiazole orange to triplex and G-quadruplex DNA | Biochemistry | 2010 | 126 |
Paclitaxel-clusters coated with hyaluronan as selective tumor-targeted nanovectors | Biomaterials | 2010 | 123 |
Hearing impairment: a panoply of genes and functions | Neuron | 2010 | 114 |
Chromatin density and splicing destiny: on the cross-talk between chromatin structure and splicing | EMBO Journal | 2010 | 113 |
Broad band enhancement of light absorption in photosystem I by metal nanoparticle antennas | Nano Letters | 2010 | 106 |
Linearization of the bradford protein assay | Journal of Visualized Experiments | 2010 | 103 |
Progression of normotensive adolescents to hypertensive adults: a study of 26,980 teenagers | Hypertension | 2010 | 102 |
β-Barrel topology of Alzheimer's β-amyloid ion channels | Journal of Molecular Biology | 2010 | 101 |
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 93 |
Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53 | Leukemia | 2010 | 92 |
Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51 | American Journal of Human Genetics | 2010 | 82 |
Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa | American Journal of Human Genetics | 2010 | 78 |
Role of CREB in modulation of TNFalpha and IL-10 expression in LPS-stimulated RAW264.7 macrophages | Molecular Immunology | 2010 | 73 |
Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families | European Journal of Human Genetics | 2010 | 68 |