| # | Title | Journal | Year | Citations |
|---|
| 1 | Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats | Acta Neuropathologica | 2014 | 708 |
| 2 | Inner filter effect-based fluorescent sensing systems: A review | Analytica Chimica Acta | 2018 | 489 |
| 3 | Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science | Cancer Medicine | 2019 | 461 |
| 4 | Widespread and Functional RNA Circularization in Localized Prostate Cancer | Cell | 2019 | 317 |
| 5 | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 266 |
| 6 | The cell cycle in stem cell proliferation, pluripotency and differentiation | Nature Cell Biology | 2019 | 233 |
| 7 | α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice | Redox Biology | 2018 | 225 |
| 8 | Dual-stimuli responsive hyaluronic acid-conjugated mesoporous silica for targeted delivery to CD44-overexpressing cancer cells | Acta Biomaterialia | 2015 | 196 |
| 9 | Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications | Frontiers in Neuroscience | 2018 | 178 |
| 10 | Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation | Scientific Reports | 2013 | 158 |
| 11 | Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain | Neurochemistry International | 2013 | 151 |
| 12 | Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis | Antioxidants and Redox Signaling | 2019 | 139 |
| 13 | Amino-functionalized green fluorescent carbon dots as surface energy transfer biosensors for hyaluronidase | Nanoscale | 2015 | 130 |
| 14 | LncRNA PVT1 Facilitates Tumorigenesis and Progression of Glioma via Regulation of MiR-128-3p/GREM1 Axis and BMP Signaling Pathway | Neurotherapeutics | 2018 | 129 |
| 15 | Graphene Quantum Dot/Silver Nanoparticle Hybrids with Oxidase Activities for Antibacterial Application | ACS Biomaterials Science and Engineering | 2017 | 123 |
| 16 | Meta-Analysis of Randomized Controlled Trials on the Efficacy and Safety of Donepezil, Galantamine, Rivastigmine, and Memantine for the Treatment of Alzheimer’s Disease | Frontiers in Neuroscience | 2019 | 109 |
| 17 | RVG-Peptide-Linked Trimethylated Chitosan for Delivery of siRNA to the Brain | Biomacromolecules | 2014 | 106 |
| 18 | Hybrid Lipid-Capped Mesoporous Silica for Stimuli-Responsive Drug Release and Overcoming Multidrug Resistance | ACS Applied Materials & Interfaces | 2015 | 104 |
| 19 | Iron and copper as virulence modulators in human fungal pathogens | Molecular Microbiology | 2014 | 103 |
| 20 | Reciprocal functions of Cryptococcus neoformans copper homeostasis machinery during pulmonary infection and meningoencephalitis | Nature Communications | 2014 | 96 |
| 21 | Urolithins Attenuate LPS-Induced Neuroinflammation in BV2Microglia via MAPK, Akt, and NF-κB Signaling Pathways | Journal of Agricultural and Food Chemistry | 2018 | 96 |
| 22 | Metal ions influx is a double edged sword for the pathogenesis of Alzheimer’s disease | Ageing Research Reviews | 2017 | 94 |
| 23 | Gadolinium-chelate functionalized bismuth nanotheranostic agent for in vivo MRI/CT/PAI imaging-guided photothermal cancer therapy | Biomaterials | 2018 | 94 |
| 24 | Dual-emission carbon dots for ratiometric detection of Fe3+ ions and acid phosphatase | Analytica Chimica Acta | 2020 | 93 |
| 25 | Effects of SARS‐CoV‐2 mutations on protein structures and intraviral protein–protein interactions | Journal of Medical Virology | 2021 | 85 |
| 26 | Metabolic response of maize (Zea mays L.) plants to combined drought and salt stress | Plant and Soil | 2015 | 84 |
| 27 | Aggravation of Alzheimer's disease due to the COX‐2‐mediated reciprocal regulation of IL‐1β and Aβ between glial and neuron cells | Aging Cell | 2014 | 83 |
| 28 | The Role of Copper Homeostasis at the Host-Pathogen Axis: From Bacteria to Fungi | International Journal of Molecular Sciences | 2019 | 82 |
| 29 | A novel ratiometric fluorescent probe for detection of iron ions and zinc ions based on dual-emission carbon dots | Sensors and Actuators B: Chemical | 2019 | 79 |
| 30 | Transcription Factors SOD7/NGAL2 and DPA4/NGAL3 Act Redundantly to Regulate Seed Size by Directly Repressing KLU Expression in Arabidopsis thaliana | Plant Cell | 2015 | 77 |
| 31 | Natural potential therapeutic agents of neurodegenerative diseases from the traditional herbal medicine Chinese Dragon׳s Blood | Journal of Ethnopharmacology | 2014 | 76 |
| 32 | Dl-3-n-butylphthalide-induced upregulation of antioxidant defense is involved in the enhancement of cross talk between CREB and Nrf2 in an Alzheimer's disease mouse model | Neurobiology of Aging | 2016 | 75 |
| 33 | Diisonitrile Natural Product SF2768 Functions As a Chalkophore That Mediates Copper Acquisition in Streptomyces thioluteus | ACS Chemical Biology | 2017 | 75 |
| 34 | Synthesis of highly stable red-emissive carbon polymer dots by modulated polymerization: from the mechanism to application in intracellular pH imaging | Nanoscale | 2018 | 75 |
| 35 | Intranasal Lactoferrin Enhances α-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1α Pathways in an Alzheimer’s Disease Mouse Model | Neuropsychopharmacology | 2017 | 72 |
| 36 | Erythrocyte membrane-encapsulated celecoxib improves the cognitive decline of Alzheimer's disease by concurrently inducing neurogenesis and reducing apoptosis in APP/PS1 transgenic mice | Biomaterials | 2017 | 72 |
| 37 | A novel fluorometric and colorimetric sensor for iodide determination using DNA-templated gold/silver nanoclusters | Biosensors and Bioelectronics | 2017 | 70 |
| 38 | Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice | Redox Biology | 2019 | 70 |
| 39 | Self-Powered Implantable Skin-Like Glucometer for Real-Time Detection of Blood Glucose Level In Vivo | Nano-Micro Letters | 2018 | 68 |
| 40 | Tumor-Targeting Peptides: Ligands for Molecular Imaging and Therapy | Anti-Cancer Agents in Medicinal Chemistry | 2018 | 68 |
| 41 | A phosphorescent probe for in vivo imaging in the second near-infrared window | Nature Biomedical Engineering | 2022 | 67 |
| 42 | <p>Transferrin-Modified Osthole PEGylated Liposomes Travel the Blood-Brain Barrier and Mitigate Alzheimer’s Disease-Related Pathology in APP/PS-1 Mice</p> | International Journal of Nanomedicine | 2020 | 65 |
| 43 | Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice | Experimental Neurology | 2016 | 64 |
| 44 | Gut Inflammation in Association With Pathogenesis of Parkinson’s Disease | Frontiers in Molecular Neuroscience | 2019 | 63 |
| 45 | Microbiome changes: an indicator of Parkinson’s disease? | Translational Neurodegeneration | 2019 | 61 |
| 46 | Violapyrones A–G, α-Pyrone Derivatives from Streptomyces violascens Isolated from Hylobates hoolock Feces | Journal of Natural Products | 2013 | 60 |
| 47 | Metabolic response of maize plants to multi‐factorial abiotic stresses | Plant Biology | 2016 | 60 |
| 48 | Fluid shear stress‐induced osteoarthritis: roles of cyclooxygenase‐2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases | FASEB Journal | 2013 | 59 |
| 49 | Melatonin inhibiting the survival of human gastric cancer cells under ER stress involving autophagy and Ras‐Raf‐MAPK signalling | Journal of Cellular and Molecular Medicine | 2021 | 59 |
| 50 | Minocycline protects against lipopolysaccharide-induced cognitive impairment in mice | Psychopharmacology | 2016 | 55 |
