Alternative splicing and evolution: diversification, exon definition and function | Nature Reviews Genetics | 2010 | 705 |
Induced fit, conformational selection and independent dynamic segments: an extended view of binding events | Trends in Biochemical Sciences | 2010 | 617 |
The genome-wide structure of the Jewish people | Nature | 2010 | 295 |
Sub-angstrom modeling of complexes between flexible peptides and globular proteins | Proteins: Structure, Function and Bioinformatics | 2010 | 273 |
Zinc ions promote Alzheimer Abeta aggregation via population shift of polymorphic states | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 234 |
Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82 | American Journal of Human Genetics | 2010 | 223 |
ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage | Science Signaling | 2010 | 212 |
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB | Nature Structural and Molecular Biology | 2010 | 181 |
Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 176 |
Enzyme dynamics point to stepwise conformational selection in catalysis | Current Opinion in Chemical Biology | 2010 | 169 |
Expander: from expression microarrays to networks and functions | Nature Protocols | 2010 | 165 |
Allostery and population shift in drug discovery | Current Opinion in Pharmacology | 2010 | 163 |
Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response | Cell Cycle | 2010 | 147 |
FiberDock: Flexible induced-fit backbone refinement in molecular docking | Proteins: Structure, Function and Bioinformatics | 2010 | 144 |
Nanoparticle-induced vascular blockade in human prostate cancer | Blood | 2010 | 130 |
Can self-inhibitory peptides be derived from the interfaces of globular protein-protein interactions? | Proteins: Structure, Function and Bioinformatics | 2010 | 124 |
Hearing impairment: a panoply of genes and functions | Neuron | 2010 | 114 |
Chromatin density and splicing destiny: on the cross-talk between chromatin structure and splicing | EMBO Journal | 2010 | 113 |
Mechanisms of transcription factor selectivity | Trends in Genetics | 2010 | 109 |
Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women | International Journal of Cancer | 2010 | 104 |
β-Barrel topology of Alzheimer's β-amyloid ion channels | Journal of Molecular Biology | 2010 | 101 |
An integrated suite of fast docking algorithms | Proteins: Structure, Function and Bioinformatics | 2010 | 100 |
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 93 |
Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53 | Leukemia | 2010 | 92 |
Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51 | American Journal of Human Genetics | 2010 | 82 |