# | Title | Journal | Year | Citations |
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1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
2 | ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage | Science | 2007 | 2,689 |
3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
4 | The ATM protein kinase: regulating the cellular response to genotoxic stress, and more | Nature Reviews Molecular Cell Biology | 2013 | 1,340 |
5 | Vaccine hesitancy: the next challenge in the fight against COVID-19 | European Journal of Epidemiology | 2020 | 1,290 |
6 | Alternative splicing and evolution: diversification, exon definition and function | Nature Reviews Genetics | 2010 | 921 |
7 | ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin | Molecular Cell | 2008 | 777 |
8 | Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics | Drug Development Research | 2020 | 636 |
9 | Chromatin organization marks exon-intron structure | Nature Structural and Molecular Biology | 2009 | 569 |
10 | Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells | Cell Stem Cell | 2011 | 563 |
11 | The alternative role of DNA methylation in splicing regulation | Trends in Genetics | 2015 | 458 |
12 | Context is everything: aneuploidy in cancer | Nature Reviews Genetics | 2020 | 407 |
13 | Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation | Cell | 2017 | 372 |
14 | The genome-wide structure of the Jewish people | Nature | 2010 | 369 |
15 | Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks | Molecular Cell | 2011 | 347 |
16 | deepDR: a network-based deep learning approach toin silicodrug repositioning | Bioinformatics | 2019 | 343 |
17 | A Dynamic Interface between Vacuoles and Mitochondria in Yeast | Developmental Cell | 2014 | 321 |
18 | Expert specification of the ACMG/AMP variant interpretation guidelines for genetic hearing loss | Human Mutation | 2018 | 312 |
19 | Comparative Analysis Identifies Exonic Splicing Regulatory Sequences—The Complex Definition of Enhancers and Silencers | Molecular Cell | 2006 | 275 |
20 | Generation of Insulin-Producing Cells from Human Bone Marrow Mesenchymal Stem Cells by Genetic Manipulation | Stem Cells | 2007 | 265 |
21 | Whole Exome Sequencing and Homozygosity Mapping Identify Mutation in the Cell Polarity Protein GPSM2 as the Cause of Nonsyndromic Hearing Loss DFNB82 | American Journal of Human Genetics | 2010 | 261 |
22 | Ataxia Telangiectasia Mutated (ATM) Is Essential for DNA-PKcs Phosphorylations at the Thr-2609 Cluster upon DNA Double Strand Break | Journal of Biological Chemistry | 2007 | 257 |
23 | Proteomic maps of breast cancer subtypes | Nature Communications | 2016 | 256 |
24 | Tumor macrophages are pivotal constructors of tumor collagenous matrix | Journal of Experimental Medicine | 2016 | 253 |
25 | Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition | Cell Reports | 2012 | 249 |
26 | Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury | ACS Nano | 2019 | 246 |
27 | ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA Damage | Science Signaling | 2010 | 245 |
28 | Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial | Lancet Neurology, The | 2014 | 245 |
29 | Refined Geographic Distribution of the Oriental ALDH2*504Lys (nee 487Lys) Variant | Annals of Human Genetics | 2009 | 232 |
30 | DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon–intron structure | Genome Research | 2013 | 222 |
31 | Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB | Nature Structural and Molecular Biology | 2010 | 218 |
32 | Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence | Cell | 2019 | 206 |
33 | Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome | Genome Biology | 2007 | 201 |
34 | Activity-Dependent Neuroprotective Protein Snippet NAP Reduces Tau Hyperphosphorylation and Enhances Learning in a Novel Transgenic Mouse Model | Journal of Pharmacology and Experimental Therapeutics | 2007 | 199 |
35 | Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer | Journal of Experimental Medicine | 2018 | 190 |
36 | Pax6: A multi-level regulator of ocular development | Progress in Retinal and Eye Research | 2012 | 188 |
37 | Alternative splicing: current perspectives | BioEssays | 2008 | 186 |
38 | In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing | Diabetes | 2008 | 185 |
39 | CAMTAs: Calmodulin‐binding transcription activators from plants to human | FEBS Letters | 2007 | 184 |
40 | Expander: from expression microarrays to networks and functions | Nature Protocols | 2010 | 183 |
41 | Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families | Genome Biology | 2011 | 183 |
42 | HP1 Is Involved in Regulating the Global Impact of DNA Methylation on Alternative Splicing | Cell Reports | 2015 | 179 |
43 | Hearing Loss: Mechanisms Revealed by Genetics and Cell Biology | Annual Review of Genetics | 2009 | 178 |
44 | Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response | Cell Cycle | 2010 | 178 |
45 | Beyond ATM: The protein kinase landscape of the DNA damage response | FEBS Letters | 2011 | 175 |
46 | RNA-editing-mediated exon evolution | Genome Biology | 2007 | 174 |
47 | Lam6 Regulates the Extent of Contacts between Organelles | Cell Reports | 2015 | 173 |
48 | Autophagy has a key role in the pathophysiology of schizophrenia | Molecular Psychiatry | 2015 | 173 |
49 | MicroRNAs are essential for development and function of inner ear hair cells in vertebrates | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 169 |
50 | Large-scale comparative analysis of splicing signals and their corresponding splicing factors in eukaryotes | Genome Research | 2008 | 161 |