| Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues | Journal of Molecular Biology | 2005 | 394 |
| Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review | American Journal of Epidemiology | 2005 | 319 |
| PRISM: protein interactions by structural matching | Nucleic Acids Research | 2005 | 167 |
| Geometry-based flexible and symmetric protein docking | Proteins: Structure, Function and Bioinformatics | 2005 | 155 |
| Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 145 |
| Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype | Diabetes | 2005 | 141 |
| Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling | Journal of Biological Chemistry | 2005 | 123 |
| Apolipoprotein E4 enhances brain inflammation by modulation of the NF-kappaB signaling cascade | Neurobiology of Disease | 2005 | 115 |
| ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation | Cell Cycle | 2005 | 115 |
| NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP) | CNS Neuroscience & Therapeutics | 2005 | 108 |
| DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation | Molecular and Cellular Biology | 2005 | 107 |
| Functional development of the zebrafish pineal gland: light-induced expression of period2 is required for onset of the circadian clock | Journal of Neuroendocrinology | 2005 | 106 |
| Energy landscape of amyloidogenic peptide oligomerization by parallel-tempering molecular dynamics simulation: significant role of Asn ladder | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 106 |
| Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education | Pharmacogenomics Journal | 2005 | 100 |
| PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase | American Journal of Physiology - Endocrinology and Metabolism | 2005 | 90 |
| Accurate identification of alternatively spliced exons using support vector machine | Bioinformatics | 2005 | 89 |
| Protein-protein interactions: organization, cooperativity and mapping in a bottom-up Systems Biology approach | Physical Biology | 2005 | 84 |
| Human-mouse comparative analysis reveals that branch-site plasticity contributes to splicing regulation | Human Molecular Genetics | 2005 | 81 |
| Genetic dissection of Pax6 dosage requirements in the developing mouse eye | Human Molecular Genetics | 2005 | 68 |
| A comparative study of amyloid fibril formation by residues 15-19 of the human calcitonin hormone: a single beta-sheet model with a small hydrophobic core | Journal of Molecular Biology | 2005 | 67 |
| Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis | Genome Biology | 2005 | 62 |
| Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation | Developmental Dynamics | 2005 | 62 |
| How similar are protein folding and protein binding nuclei? Examination of vibrational motions of energy hot spots and conserved residues | Biophysical Journal | 2005 | 60 |
| Favorable scaffolds: proteins with different sequence, structure and function may associate in similar ways | Protein Engineering, Design and Selection | 2005 | 57 |
| The importance of being divisible by three in alternative splicing | Nucleic Acids Research | 2005 | 51 |
