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Top Articles

#TitleJournalYearCitations
1High resolution acrylamide gel electrophoresis of histonesArchives of Biochemistry and Biophysics19692,512
2Very fast empirical prediction and rationalization of protein pKa valuesProteins: Structure, Function and Bioinformatics20051,771
3The Genome of the African Trypanosome Trypanosoma bruceiScience20051,496
4How crowded is the cytoplasm?Cell1982781
5Determination of glycogenArchives of Biochemistry and Biophysics1957727
6Comparative Genomics of Trypanosomatid Parasitic ProtozoaScience2005713
7Proteasomes and their kin: proteases in the machine ageNature Reviews Molecular Cell Biology2004676
8A cryptic protease couples deubiquitination and degradation by the proteasomeNature2002667
9Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitroGenes and Development1997642
10Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial CytoplasmPLoS Computational Biology2010612
11P-TEFb, a Cyclin-Dependent Kinase Controlling Elongation by RNA Polymerase IIMolecular and Cellular Biology2000610
12Protein Structure and the Energetics of Protein StabilityChemical Reviews1997609
13Regulation of pyruvate metabolism and human diseaseCellular and Molecular Life Sciences2014587
14Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain KinaseJournal of Biological Chemistry1996559
15Crystal Structure of a UBP-Family Deubiquitinating Enzyme in Isolation and in Complex with Ubiquitin AldehydeCell2002554
16Recombinant replication protein A: expression, complex formation, and functional characterizationJournal of Biological Chemistry1994534
17RNA Polymerase II Elongation ControlAnnual Review of Biochemistry2012505
18Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to IronScience2003498
19Nicotinamide riboside is uniquely and orally bioavailable in mice and humansNature Communications2016498
20Recombinant replication protein A: expression, complex formation, and functional characterizationJournal of Biological Chemistry1994472
21Identification of multiple cyclin subunits of human P-TEFbGenes and Development1998463
22Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive ElongationJournal of Biological Chemistry1995445
23Role of RNase H in hybrid-arrested translation by antisense oligonucleotides.Proceedings of the National Academy of Sciences of the United States of America1988442
24Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasomeNature1997423
25DNA position-specific repression of transcription by a Drosophila zinc finger protein.Genes and Development1992420
26Flavopiridol Inhibits P-TEFb and Blocks HIV-1 ReplicationJournal of Biological Chemistry2000408
27Measurement of protein concentration with interferences opticsAnalytical Biochemistry1969407
28Nucleotide sequence of the yeast plasmidNature1980407
29RPA involvement in the damage-recognition and incision steps of nucleotide excision repairNature1995405
30Action of epoxyeicosatrienoic acids on cellular functionAmerican Journal of Physiology - Cell Physiology2007405
31Identification of a Ras Palmitoyltransferase inSaccharomyces cerevisiaeJournal of Biological Chemistry2002398
32Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)Chemical Reviews2014391
33Rapid protein kinase assay using phosphocellulose-paper absorptionAnalytical Biochemistry1975360
34Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14EMBO Journal2005359
35Arachidonic acid cytochrome P450 epoxygenase pathwayJournal of Lipid Research2009334
36Rapid purification of lactate dehydrogenase from rat liver and hepatoma: A new approachArchives of Biochemistry and Biophysics1974332
37Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetryBiophysical Journal1996316
38Vinculin in cell–cell and cell–matrix adhesionsCellular and Molecular Life Sciences2017314
39Astrocytes, Not Neurons, Produce Docosahexaenoic Acid (22:6?-3) and Arachidonic Acid (20:4?-6)Journal of Neurochemistry1991308
40Haem exposure as the determinate of oxidation–reduction potential of haem proteinsNature1978306
41Hydroxyeicosatetraenoic acids (HETEs)Progress in Lipid Research1988302
42Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexesEMBO Journal1999301
43Control of formation of two distinct classes of RNA polymerase II elongation complexes.Molecular and Cellular Biology1992300
44A new histone found only in mammalian tissues with little cell divisionBiochemical and Biophysical Research Communications1969298
45Hidden dynamic allostery in a PDZ domainProceedings of the National Academy of Sciences of the United States of America2009296
46DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-RasJournal of Biological Chemistry2005295
47Microheterogeneity and paucidispersity of glycoproteinsCarbohydrate Research1970291
48Binding properties of replication protein A from human and yeast cells.Molecular and Cellular Biology1992290
49Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeastYeast1993289
50Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1Nature Cell Biology2006282