| # | Title | Journal | Year | Citations |
|---|
| 1 | A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation | Cell | 2008 | 951 |
| 2 | An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2007 | 695 |
| 3 | Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology | Cancer and Metastasis Reviews | 2004 | 584 |
| 4 | Optimal Surface Segmentation in Volumetric Images-A Graph-Theoretic Approach | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2006 | 572 |
| 5 | A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases | International Journal of Radiation Oncology Biology Physics | 2002 | 515 |
| 6 | Lymph protects metastasizing melanoma cells from ferroptosis | Nature | 2020 | 484 |
| 7 | Role for DNA methylation in the control of cell type–specific maspin expression | Nature Genetics | 2002 | 403 |
| 8 | Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip | Nature Genetics | 2008 | 382 |
| 9 | Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation | Biochemical Journal | 2009 | 378 |
| 10 | NADPH Oxidases of the Brain: Distribution, Regulation, and Function | Antioxidants and Redox Signaling | 2006 | 335 |
| 11 | Redox Control of the Cell Cycle in Health and Disease | Antioxidants and Redox Signaling | 2009 | 326 |
| 12 | O 2 ⋅− and H 2 O 2 -Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate | Cancer Cell | 2017 | 316 |
| 13 | Intraretinal Layer Segmentation of Macular Optical Coherence Tomography Images Using Optimal 3-D Graph Search | IEEE Transactions on Medical Imaging | 2008 | 300 |
| 14 | Reactive Oxygen Species in Normal and Tumor Stem Cells | Advances in Cancer Research | 2014 | 291 |
| 15 | A redox cycle within the cell cycle: ring in the old with the new | Oncogene | 2007 | 267 |
| 16 | α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II | Oncogene | 2008 | 266 |
| 17 | Manganese Superoxide Dismutase-Mediated Gene Expression in Radiation-Induced Adaptive Responses | Molecular and Cellular Biology | 2003 | 263 |
| 18 | The Redox Basis of Epigenetic Modifications: From Mechanisms to Functional Consequences | Antioxidants and Redox Signaling | 2011 | 242 |
| 19 | Role of Glutaredoxin in Metabolic Oxidative Stress | Journal of Biological Chemistry | 2002 | 240 |
| 20 | DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway | Cell Death and Disease | 2012 | 235 |
| 21 | Mitochondrial O2⋅¯ and H2O2 Mediate Glucose Deprivation-induced Stress in Human Cancer Cells | Journal of Biological Chemistry | 2005 | 225 |
| 22 | Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress | Environmental Health Perspectives | 2014 | 221 |
| 23 | An epigenetic perspective on the free radical theory of development | Free Radical Biology and Medicine | 2007 | 218 |
| 24 | 2-Deoxy-d-Glucose Combined with Cisplatin Enhances Cytotoxicity via Metabolic Oxidative Stress in Human Head and Neck Cancer Cells | Cancer Research | 2007 | 215 |
| 25 | Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism | Redox Biology | 2014 | 206 |
| 26 | An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses | Radiotherapy and Oncology | 2019 | 189 |
| 27 | Three-Dimensional Analysis of Retinal Layer Texture: Identification of Fluid-Filled Regions in SD-OCT of the Macula | IEEE Transactions on Medical Imaging | 2010 | 186 |
| 28 | Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts | Clinical Cancer Research | 2013 | 180 |
| 29 | Redox regulation of the G1 to S phase transition in the mouse embryo fibroblast cell cycle | Cancer Research | 2003 | 180 |
| 30 | Mutation of Succinate Dehydrogenase Subunit C Results in Increased O2·−, Oxidative Stress, and Genomic Instability | Cancer Research | 2006 | 178 |
| 31 | Activation of Matrix Metalloproteinase-2 by Overexpression of Manganese Superoxide Dismutase in Human Breast Cancer MCF-7 Cells Involves Reactive Oxygen Species | Journal of Biological Chemistry | 2002 | 169 |
| 32 | Overexpression of manganese or copper–zinc superoxide dismutase inhibits breast cancer growth | Free Radical Biology and Medicine | 2006 | 169 |
| 33 | Three-Dimensional Segmentation of Fluid-Associated Abnormalities in Retinal OCT: Probability Constrained Graph-Search-Graph-Cut | IEEE Transactions on Medical Imaging | 2012 | 169 |
| 34 | SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells | Free Radical Biology and Medicine | 2014 | 156 |
| 35 | Thioredoxin reductase as a novel molecular target for cancer therapy | Cancer Letters | 2006 | 148 |
| 36 | Segmentation of the Optic Disc in 3-D OCT Scans of the Optic Nerve Head | IEEE Transactions on Medical Imaging | 2010 | 144 |
| 37 | 4-D Cardiac MR Image Analysis: Left and Right Ventricular Morphology and Function | IEEE Transactions on Medical Imaging | 2010 | 143 |
| 38 | Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cells | Oncogene | 2005 | 142 |
| 39 | Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy | Physiological Genomics | 2006 | 135 |
| 40 | 2-Deoxy-d-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer | Free Radical Biology and Medicine | 2008 | 134 |
| 41 | Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress | Aging | 2011 | 132 |
| 42 | Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity | Journal of Biological Chemistry | 2020 | 132 |
| 43 | Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1α and vascular endothelial growth factor | Oncogene | 2005 | 130 |
| 44 | Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth | Aging Cell | 2008 | 127 |
| 45 | Mechanisms of H2O2-induced oxidative stress in endothelial cells | Free Radical Biology and Medicine | 2006 | 123 |
| 46 | Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2 | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 121 |
| 47 | Image Guided Radiation Therapy (IGRT) Technologies for Radiation Therapy Localization and Delivery | International Journal of Radiation Oncology Biology Physics | 2013 | 120 |
| 48 | Tracking lung tissue motion and expansion/compression with inverse consistent image registration and spirometry | Medical Physics | 2007 | 114 |
| 49 | Calcium-dependent Modulation of Poly(ADP-ribose) Polymerase-1 Alters Cellular Metabolism and DNA Repair | Journal of Biological Chemistry | 2006 | 113 |
| 50 | Optimal Co-Segmentation of Tumor in PET-CT Images With Context Information | IEEE Transactions on Medical Imaging | 2013 | 112 |
