| # | Title | Journal | Year | Citations |
|---|
| 1 | Ridge-Based Vessel Segmentation in Color Images of the Retina | IEEE Transactions on Medical Imaging | 2004 | 2,914 |
| 2 | A common haplotype in the complement regulatory gene factor H ( HF1/CFH ) predisposes individuals to age-related macular degeneration | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 1,867 |
| 3 | Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial | Lancet, The | 2017 | 1,250 |
| 4 | Retinal Imaging and Image Analysis | IEEE Reviews in Biomedical Engineering | 2010 | 1,021 |
| 5 | Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration | Nature Genetics | 2006 | 1,001 |
| 6 | A role for local inflammation in the formation of drusen in the aging eye | American Journal of Ophthalmology | 2002 | 986 |
| 7 | Drusen associated with aging and age‐related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease | FASEB Journal | 2000 | 833 |
| 8 | Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices | Npj Digital Medicine | 2018 | 796 |
| 9 | Primary Open-Angle Glaucoma | New England Journal of Medicine | 2009 | 747 |
| 10 | Age‐related macular degeneration—emerging pathogenetic and therapeutic concepts | Annals of Medicine | 2006 | 546 |
| 11 | Automated 3-D Intraretinal Layer Segmentation of Macular Spectral-Domain Optical Coherence Tomography Images | IEEE Transactions on Medical Imaging | 2009 | 535 |
| 12 | Ocular manifestations of giant cell arteritis | American Journal of Ophthalmology | 1998 | 523 |
| 13 | Ischemic optic neuropathy | Progress in Retinal and Eye Research | 2009 | 494 |
| 14 | The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration | Survey of Ophthalmology | 2006 | 443 |
| 15 | Prevalent misconceptions about acute retinal vascular occlusive disorders | Progress in Retinal and Eye Research | 2005 | 418 |
| 16 | Retinopathy Online Challenge: Automatic Detection of Microaneurysms in Digital Color Fundus Photographs | IEEE Transactions on Medical Imaging | 2010 | 414 |
| 17 | Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease | FASEB Journal | 2000 | 400 |
| 18 | Central retinal artery occlusion. | Experimental Eye Research | 2004 | 380 |
| 19 | Central Retinal Artery Occlusion: Visual Outcome | American Journal of Ophthalmology | 2005 | 374 |
| 20 | Membranoproliferative Glomerulonephritis Type II (Dense Deposit Disease) | Journal of the American Society of Nephrology: JASN | 2005 | 354 |
| 21 | Peroxisome biogenesis disorders in the Zellweger spectrum: An overview of current diagnosis, clinical manifestations, and treatment guidelines | Molecular Genetics and Metabolism | 2016 | 314 |
| 22 | Occult giant cell arteritis: Ocular manifestations | American Journal of Ophthalmology | 1998 | 303 |
| 23 | Characterization of β amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration | Experimental Eye Research | 2004 | 303 |
| 24 | Intraretinal Layer Segmentation of Macular Optical Coherence Tomography Images Using Optimal 3-D Graph Search | IEEE Transactions on Medical Imaging | 2008 | 300 |
| 25 | Retinal Artery OcclusionAssociated Systemic and Ophthalmic Abnormalities | Ophthalmology | 2009 | 296 |
| 26 | Role of Nocturnal Arterial Hypotension in Optic Nerve Head Ischemic Disorders | Ophthalmologica | 1999 | 289 |
| 27 | Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy | Graefe's Archive for Clinical and Experimental Ophthalmology | 2008 | 244 |
| 28 | Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation–Associated Inherited Retinal Dystrophy | Ophthalmology | 2019 | 239 |
| 29 | Ocular vascular occlusive disorders: Natural history of visual outcome | Progress in Retinal and Eye Research | 2014 | 238 |
| 30 | Diagnosis and Grading of Papilledema in Patients With Raised Intracranial Pressure Using Optical Coherence Tomography vs Clinical Expert Assessment Using a Clinical Staging Scale | JAMA Ophthalmology | 2010 | 231 |
| 31 | Visual improvement with corticosteroid therapy in giant cell arteritis. Report of a large study and review of literature | Acta Ophthalmologica | 2002 | 222 |
| 32 | Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein | Journal of Immunology | 2007 | 220 |
| 33 | Multiscale AM-FM Methods for Diabetic Retinopathy Lesion Detection | IEEE Transactions on Medical Imaging | 2010 | 220 |
| 34 | Extended haplotypes in the complement factor H (CFH) and CFH‐related (CFHR) family of genes protect against age‐related macular degeneration: Characterization, ethnic distribution and evolutionary implications | Annals of Medicine | 2006 | 217 |
| 35 | ABCB5 is a limbal stem cell gene required for corneal development and repair | Nature | 2014 | 217 |
| 36 | Structure and composition of drusen associated with glomerulonephritis: Implications for the role of complement activation in drusen biogenesis | Eye | 2001 | 214 |
| 37 | Toward a Clinical Protocol for Assessing Rod, Cone, and Melanopsin Contributions to the Human Pupil Response | | 2011 | 213 |
| 38 | Natural History of Visual Outcome in Central Retinal Vein Occlusion | Ophthalmology | 2011 | 213 |
| 39 | ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 213 |
| 40 | Orbital vascular anatomy | Eye | 2006 | 211 |
| 41 | Posterior ischaemic optic neuropathy: clinical features, pathogenesis, and management | Eye | 2004 | 210 |
| 42 | Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 204 |
| 43 | Nonarteritic Anterior Ischemic Optic Neuropathy | Ophthalmology | 2008 | 196 |
| 44 | Visual deterioration in giant cell arteritis patients while on high doses of corticosteroid therapy | Ophthalmology | 2003 | 195 |
| 45 | Global Retinoblastoma Presentation and Analysis by National Income Level | JAMA Oncology | 2020 | 192 |
| 46 | Oxidative Stress and the Regulation of Complement Activation in Human Glaucoma | | 2010 | 191 |
| 47 | Posterior Ciliary Artery Circulation in Health and Disease The Weisenfeld Lecture | | 2004 | 189 |
| 48 | Copy number variations on chromosome 12q14 in patients with normal tension glaucoma | Human Molecular Genetics | 2011 | 189 |
| 49 | Pathogenesis of optic disc edema in raised intracranial pressure | Progress in Retinal and Eye Research | 2016 | 189 |
| 50 | Three-Dimensional Analysis of Retinal Layer Texture: Identification of Fluid-Filled Regions in SD-OCT of the Macula | IEEE Transactions on Medical Imaging | 2010 | 186 |
