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Top Articles

#TitleJournalYearCitations
1Cell adhesion: integrating cytoskeletal dynamics and cellular tensionNature Reviews Molecular Cell Biology20101,665
2pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.Proceedings of the National Academy of Sciences of the United States of America19921,416
3FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassemblyNature Cell Biology20041,175
4Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase KinaseScience1993982
5Mechanotransduction in vascular physiology and atherogenesisNature Reviews Molecular Cell Biology2009976
6Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and NematodesCell2000800
7The multifarious, multireplicon Burkholderia cepacia complexNature Reviews Microbiology2005767
8HDAC6 Modulates Cell Motility by Altering the Acetylation Level of CortactinMolecular Cell2007626
9A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesisNature2002618
10Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movementOncogene2000612
11Autophosphorylation of the Focal Adhesion Kinase, ppl25FAK, Directs SH2-Dependent Binding of pp60srcMolecular and Cellular Biology1994590
12Engulfment of apoptotic cells: signals for a good mealNature Reviews Immunology2007571
13pp125FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for CrkMolecular and Cellular Biology1995531
14Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complexNature Cell Biology2002522
15Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.Molecular and Cellular Biology1994518
16Acetylation of histone H4 by Esa1 is required for DNA double-strand break repairNature2002513
17Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.Genes and Development1988512
18Focal adhesion kinase and associated proteinsCurrent Opinion in Cell Biology1994511
19The genome of Cryptosporidium hominisNature2004506
20Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.Journal of Cell Biology1993488
21Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinasesToxicon2005470
22A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAKNature1996460
23Phagosome maturation: going through the acid testNature Reviews Molecular Cell Biology2008447
24Clearance of apoptotic cells: implications in health and diseaseJournal of Cell Biology2010444
25Influenza virus pleiomorphy characterized by cryoelectron tomographyProceedings of the National Academy of Sciences of the United States of America2006426
26Cell-cell adhesion mediated by CD8 and MHC class I moleculesNature1988408
27Par-3 controls tight junction assembly through the Rac exchange factor Tiam1Nature Cell Biology2005408
28Cortactin: coupling membrane dynamics to cortical actin assemblyOncogene2001384
29Role of Endosomal Cathepsins in Entry Mediated by the Ebola Virus GlycoproteinJournal of Virology2006376
30An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins.Journal of Experimental Medicine1996375
31Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.Journal of Cell Biology1993371
32Signaling via Shc family adapter proteinsOncogene2001368
33Structure of Peptides Associated with Class I and Class II MHC MoleculesAnnual Review of Immunology1994365
34Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathwaysCurrent Opinion in Cell Biology1997361
35Cell Migration--Movin' OnScience1999351
36Genetic analysis of histone H4: essential role of lysines subject to reversible acetylationScience1990345
37Human H-Y: a Male-Specific Histocompatibility Antigen Derived from the SMCY ProteinScience1995345
38Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α ProductionJournal of Biological Chemistry2012343
39Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.Molecular Biology of the Cell1995331
40Insights into and speculations about snake venom metalloproteinase (SVMP) synthesis, folding and disulfide bond formation and their contribution to venom complexityFEBS Journal2008329
41The Many Mechanisms of Viral Membrane Fusion ProteinsCurrent Topics in Microbiology and Immunology2004326
42An SH3 Domain-Containing GTPase-Activating Protein for Rho and Cdc42 Associates with Focal Adhesion KinaseMolecular and Cellular Biology1996325
43Parsing the Polarity CodeNature Reviews Molecular Cell Biology2004312
44Inhibition of Cell Spreading by Expression of the C-Terminal Domain of Focal Adhesion Kinase (FAK) Is Rescued by Coexpression of Src or Catalytically Inactive FAK: a Role for Paxillin Tyrosine PhosphorylationMolecular and Cellular Biology1997310
45High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometryJournal of Biology2006308
46Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expressionEMBO Journal2002297
47The Role of Macrophage Polarization in Infectious and Inflammatory DiseasesMolecules and Cells2014294
48Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteinsCurrent Opinion in Cell Biology1996290
49microRNA-34a is tumor suppressive in brain tumors and glioma stem cellsCell Cycle2010289
50Signal transduction through integrins: A central role for focal adhesion kinase?BioEssays1995286