# | Title | Journal | Year | Citations |
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1 | Cell adhesion: integrating cytoskeletal dynamics and cellular tension | Nature Reviews Molecular Cell Biology | 2010 | 1,665 |
2 | pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 1,416 |
3 | FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly | Nature Cell Biology | 2004 | 1,175 |
4 | Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase | Science | 1993 | 982 |
5 | Mechanotransduction in vascular physiology and atherogenesis | Nature Reviews Molecular Cell Biology | 2009 | 976 |
6 | Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes | Cell | 2000 | 800 |
7 | The multifarious, multireplicon Burkholderia cepacia complex | Nature Reviews Microbiology | 2005 | 767 |
8 | HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin | Molecular Cell | 2007 | 626 |
9 | A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis | Nature | 2002 | 618 |
10 | Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement | Oncogene | 2000 | 612 |
11 | Autophosphorylation of the Focal Adhesion Kinase, ppl25FAK, Directs SH2-Dependent Binding of pp60src | Molecular and Cellular Biology | 1994 | 590 |
12 | Engulfment of apoptotic cells: signals for a good meal | Nature Reviews Immunology | 2007 | 571 |
13 | pp125FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for Crk | Molecular and Cellular Biology | 1995 | 531 |
14 | Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex | Nature Cell Biology | 2002 | 522 |
15 | Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK. | Molecular and Cellular Biology | 1994 | 518 |
16 | Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair | Nature | 2002 | 513 |
17 | Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. | Genes and Development | 1988 | 512 |
18 | Focal adhesion kinase and associated proteins | Current Opinion in Cell Biology | 1994 | 511 |
19 | The genome of Cryptosporidium hominis | Nature | 2004 | 506 |
20 | Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. | Journal of Cell Biology | 1993 | 488 |
21 | Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases | Toxicon | 2005 | 470 |
22 | A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK | Nature | 1996 | 460 |
23 | Phagosome maturation: going through the acid test | Nature Reviews Molecular Cell Biology | 2008 | 447 |
24 | Clearance of apoptotic cells: implications in health and disease | Journal of Cell Biology | 2010 | 444 |
25 | Influenza virus pleiomorphy characterized by cryoelectron tomography | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 426 |
26 | Cell-cell adhesion mediated by CD8 and MHC class I molecules | Nature | 1988 | 408 |
27 | Par-3 controls tight junction assembly through the Rac exchange factor Tiam1 | Nature Cell Biology | 2005 | 408 |
28 | Cortactin: coupling membrane dynamics to cortical actin assembly | Oncogene | 2001 | 384 |
29 | Role of Endosomal Cathepsins in Entry Mediated by the Ebola Virus Glycoprotein | Journal of Virology | 2006 | 376 |
30 | An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins. | Journal of Experimental Medicine | 1996 | 375 |
31 | Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions. | Journal of Cell Biology | 1993 | 371 |
32 | Signaling via Shc family adapter proteins | Oncogene | 2001 | 368 |
33 | Structure of Peptides Associated with Class I and Class II MHC Molecules | Annual Review of Immunology | 1994 | 365 |
34 | Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways | Current Opinion in Cell Biology | 1997 | 361 |
35 | Cell Migration--Movin' On | Science | 1999 | 351 |
36 | Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation | Science | 1990 | 345 |
37 | Human H-Y: a Male-Specific Histocompatibility Antigen Derived from the SMCY Protein | Science | 1995 | 345 |
38 | Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production | Journal of Biological Chemistry | 2012 | 343 |
39 | Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. | Molecular Biology of the Cell | 1995 | 331 |
40 | Insights into and speculations about snake venom metalloproteinase (SVMP) synthesis, folding and disulfide bond formation and their contribution to venom complexity | FEBS Journal | 2008 | 329 |
41 | The Many Mechanisms of Viral Membrane Fusion Proteins | Current Topics in Microbiology and Immunology | 2004 | 326 |
42 | An SH3 Domain-Containing GTPase-Activating Protein for Rho and Cdc42 Associates with Focal Adhesion Kinase | Molecular and Cellular Biology | 1996 | 325 |
43 | Parsing the Polarity Code | Nature Reviews Molecular Cell Biology | 2004 | 312 |
44 | Inhibition of Cell Spreading by Expression of the C-Terminal Domain of Focal Adhesion Kinase (FAK) Is Rescued by Coexpression of Src or Catalytically Inactive FAK: a Role for Paxillin Tyrosine Phosphorylation | Molecular and Cellular Biology | 1997 | 310 |
45 | High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry | Journal of Biology | 2006 | 308 |
46 | Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression | EMBO Journal | 2002 | 297 |
47 | The Role of Macrophage Polarization in Infectious and Inflammatory Diseases | Molecules and Cells | 2014 | 294 |
48 | Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins | Current Opinion in Cell Biology | 1996 | 290 |
49 | microRNA-34a is tumor suppressive in brain tumors and glioma stem cells | Cell Cycle | 2010 | 289 |
50 | Signal transduction through integrins: A central role for focal adhesion kinase? | BioEssays | 1995 | 286 |