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Top Articles

#TitleJournalYearCitations
1HKL-3000: the integration of data reduction and structure solution – from diffraction images to an initial model in minutesActa Crystallographica Section D: Biological Crystallography20061,822
2Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin PhosphatasePhysiological Reviews20031,817
3Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemiaNature Genetics19991,036
4Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosisNature2010929
5Phagocytosis of Apoptotic Neutrophils Regulates Granulopoiesis via IL-23 and IL-17Immunity2005803
6Structural and immunologic characterization of bovine, horse, and rabbit serum albuminsMolecular Immunology2012756
7Overcoming Expression and Purification Problems of RhoGDI Using a Family of “Parallel” Expression VectorsProtein Expression and Purification1999606
8Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gatingNature Structural Biology2002605
9Identification of Distinct Luminal Domains for Macromolecules, Erythrocytes, and Leukocytes Within Mammalian CapillariesCirculation Research1996526
10Targeting transcription factors in cancer — from undruggable to realityNature Reviews Cancer2019515
11Tethered Polymer-Supported Planar Lipid Bilayers for Reconstitution of Integral Membrane Proteins: Silane-Polyethyleneglycol-Lipid as a Cushion and Covalent LinkerBiophysical Journal2000493
12Crystallographic snapshot of cellulose synthesis and membrane translocationNature2013492
13Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutininNature Structural Biology2001406
14Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependentJournal of Experimental Medicine2006405
15Molecular determinants of gating at the potassium-channel selectivity filterNature Structural and Molecular Biology2006399
16Structure of outer membrane protein A transmembrane domain by NMR spectroscopyNature Structural Biology2001363
17Biological atomic force microscopy: what is achieved and what is neededAdvances in Physics1996331
18Myocardin Is a Key Regulator of CArG-Dependent Transcription of Multiple Smooth Muscle Marker GenesCirculation Research2003320
19Kruppel-like Factor 4 Abrogates Myocardin-induced Activation of Smooth Muscle Gene ExpressionJournal of Biological Chemistry2005297
20Mechanism of activation of bacterial cellulose synthase by cyclic di-GMPNature Structural and Molecular Biology2014281
21Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle.Proceedings of the National Academy of Sciences of the United States of America1996279
22Substrate-induced transmembrane signaling in the cobalamin transporter BtuBNature Structural and Molecular Biology2003274
23Outer Membrane Active Transport: Structure of the BtuB:TonB ComplexScience2006274
24Data mining of metal ion environments present in protein structuresJournal of Inorganic Biochemistry2008273
25Capillary endothelial surface layer selectively reduces plasma solute distribution volumeAmerican Journal of Physiology - Heart and Circulatory Physiology2000272
26A Transforming Growth Factor β (TGFβ) Control Element Drives TGFβ-induced Stimulation of Smooth Muscle α-Actin Gene Expression in Concert with Two CArG ElementsJournal of Biological Chemistry1997270
27Molecular Determinants of Vascular Smooth Muscle Cell DiversityCirculation Research2005269
28Permeation of the luminal capillary glycocalyx is determined by hyaluronanAmerican Journal of Physiology - Heart and Circulatory Physiology1999265
29TNF-α increases entry of macromolecules into luminal endothelial cell glycocalyxAmerican Journal of Physiology - Heart and Circulatory Physiology2000259
30Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web serverNature Protocols2014254
31Gap Junctions in the Control of Vascular FunctionAntioxidants and Redox Signaling2009248
32Toward rational protein crystallization: A Web server for the design of crystallizable protein variantsProtein Science2007247
33A Molecular Description of Cellulose BiosynthesisAnnual Review of Biochemistry2015232
34Protein crystallography for non‐crystallographers, or how to get the best (but not more) from published macromolecular structuresFEBS Journal2008231
35Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivoJournal of Clinical Investigation2005231
36Dye Tracers Define Differential Endothelial and Smooth Muscle Coupling Patterns Within the Arteriolar WallCirculation Research1995226
37Molecular Architecture of the KvAP Voltage-Dependent K+ Channel in a Lipid BilayerScience2004219
38Molecular driving forces determining potassium channel slow inactivationNature Structural and Molecular Biology2007216
39Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in miceProceedings of the National Academy of Sciences of the United States of America2001214
40Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cellsAmerican Journal of Physiology - Cell Physiology2007212
41Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow–derived cellsJournal of Clinical Investigation2003212
42Transbilayer Effects of Raft-Like Lipid Domains in Asymmetric Planar Bilayers Measured by Single Molecule TrackingBiophysical Journal2006211
43Conditional Deletion of Krüppel-Like Factor 4 Delays Downregulation of Smooth Muscle Cell Differentiation Markers but Accelerates Neointimal Formation Following Vascular InjuryCirculation Research2008211
44BcsA and BcsB form the catalytically active core of bacterial cellulose synthase sufficient for in vitro cellulose synthesisProceedings of the National Academy of Sciences of the United States of America2013211
45Elastic coupling of integral membrane protein stability to lipid bilayer forcesProceedings of the National Academy of Sciences of the United States of America2004210
46The Outer Membrane Protein OmpW Forms an Eight-stranded β-Barrel with a Hydrophobic ChannelJournal of Biological Chemistry2006204
47Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injuryJournal of Clinical Investigation2000202
48Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720Journal of Biological Chemistry2005198
49Domain coupling in asymmetric lipid bilayersBiochimica Et Biophysica Acta - Biomembranes2009194
50Energy transduction and alternating access of the mammalian ABC transporter P-glycoproteinNature2017189