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Top Articles

#TitleJournalYearCitations
1Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylaseEMBO Journal20042,413
2Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
3Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of AmericaClinical Infectious Diseases20101,260
4Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-DioxygenaseScience2002946
5KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesisNature Medicine2015869
6Surgical Risk Factors, Morbidity, and Mortality in Elderly PatientsJournal of the American College of Surgeons2006851
7Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell linesScience1994812
8Randomized Comparison of Percutaneous Repair and Surgery for Mitral RegurgitationJournal of the American College of Cardiology2015658
9Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthaseNature Medicine2002510
10Wound Infection After Elective Colorectal ResectionAnnals of Surgery2004504
11Guidelines for the Selection of Anti-infective Agents for Complicated Intra-abdominal InfectionsClinical Infectious Diseases2003464
12Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 DiabetesCell Metabolism2012410
13Diagnosis and Management of Complicated Intra-Abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of AmericaSurgical Infections2010401
14The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal InfectionSurgical Infections2017382
15Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010Journal of Vascular Surgery2014379
16Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant TherapyJournal of Clinical Oncology2022292
17A Nomogram to Predict Long-term Survival After Resection for Intrahepatic CholangiocarcinomaJAMA Surgery2014285
18Metabolites released from apoptotic cells act as tissue messengersNature2020266
19Recipient Morbidity After Living and Deceased Donor Liver Transplantation: Findings from the A2ALL Retrospective Cohort StudyAmerican Journal of Transplantation2008260
20Smooth muscle phenotypic modulation is an early event in aortic aneurysmsJournal of Thoracic and Cardiovascular Surgery2009257
21Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammationNature2013254
22Influences on Medical Student Career ChoiceArchives of Surgery2006242
23Impact of Patient Distance to Radiation Therapy on Mastectomy Use in Early-Stage Breast Cancer PatientsJournal of Clinical Oncology2005230
24Impact of a rotating empiric antibiotic schedule on infectious mortality in an intensive care unitCritical Care Medicine2001228
25Exclusion of the left atrial appendage with a novel device: Early results of a multicenter trialJournal of Thoracic and Cardiovascular Surgery2011227
26Use of National Surgical Quality Improvement Program Data as a Catalyst for Quality ImprovementJournal of the American College of Surgeons2007210
27Global, Regional, and National Burden of Calcific Aortic Valve and Degenerative Mitral Valve Diseases, 1990–2017Circulation2020206
28Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cellsOncogene2001196
29Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort studyLancet Infectious Diseases, The2012186
30Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor MicroenvironmentMolecular Cancer Therapeutics2011185
31The Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-Abdominal Infections: An Executive SummarySurgical Infections2002182
32Blood product conservation is associated with improved outcomes and reduced costs after cardiac surgeryJournal of Thoracic and Cardiovascular Surgery2013181
33Evaluation and management of geriatric traumaJournal of Trauma and Acute Care Surgery2012179
34UNI- AND MULTI-VARIATE ANALYSIS OF RISK FACTORS FOR EARLY AND LATE HEPATIC ARTERY THROMBOSIS AFTER LIVER TRANSPLANTATIONTransplantation2001176
35Functional Interdependence at the Chromatin Level between the MKK6/p38 and IGF1/PI3K/AKT Pathways during Muscle DifferentiationMolecular Cell2007174
36Incontinence rates after cutting seton treatment for anal fistulaColorectal Disease2009172
37Responsible Development and Application of Surgical Innovations: A Position Statement of the Society of University SurgeonsJournal of the American College of Surgeons2008169
38Ineffectiveness of Histone Deacetylase Inhibitors to Induce Apoptosis Involves the Transcriptional Activation of NF-κB through the Akt PathwayJournal of Biological Chemistry2003163
39Early versus late recurrence of intrahepatic cholangiocarcinoma after resection with curative intentBritish Journal of Surgery2018158
40Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomesClinical Cancer Research2001155
41Terminal modifications inhibit proteolytic degradation of an immunogenic mart-127-35 peptide: Implications for peptide vaccinesInternational Journal of Cancer1999152
42Use of Silver in the Prevention and Treatment of Infections: Silver ReviewSurgical Infections2013152
43Immunologic and Clinical Outcomes of a Randomized Phase II Trial of Two Multipeptide Vaccines for Melanoma in the Adjuvant SettingClinical Cancer Research2007149
44CLINICAL AND HISTOLOGIC PATTERNS OF EARLY GRAFT FAILURE DUE TO RECURRENT HEPATITIS C IN FOUR PATIENTS AFTER LIVER TRANSPLANTATIONTransplantation1996146
45Vaccines targeting helper T cells for cancer immunotherapyCurrent Opinion in Immunology2017145
46Genetic and Pharmacologic Disruption of Interleukin-1β Signaling Inhibits Experimental Aortic Aneurysm FormationArteriosclerosis, Thrombosis, and Vascular Biology2013143
47Tumor Recurrence After Complete Resection for Non-Small Cell Lung CancerAnnals of Thoracic Surgery2012142
48Initial Experience of Sequential Surgical Epicardial-Catheter Endocardial Ablation for Persistent and Long-Standing Persistent Atrial Fibrillation With Long-Term Follow-UpAnnals of Thoracic Surgery2011141
49Morbidity, Mortality, Cost, and Survival Estimates of Gastrointestinal Anastomotic LeaksJournal of the American College of Surgeons2015141
50Overexpression of Collagenase 1 (MMP-1) Is Mediated by the ERK Pathway in Invasive Melanoma CellsJournal of Biological Chemistry2004137