| # | Title | Journal | Year | Citations |
|---|
| 1 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 2 | STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration | BMJ Open | 2016 | 1,324 |
| 3 | Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex | Molecular and Cellular Biology | 2004 | 1,083 |
| 4 | Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease | Hepatology | 1999 | 1,053 |
| 5 | Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease | Nature | 2018 | 839 |
| 6 | Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative | Clinical Chemistry | 2003 | 805 |
| 7 | BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module | Nature | 2007 | 714 |
| 8 | A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis | Nature | 2002 | 618 |
| 9 | Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression | Molecular and Cellular Biology | 2002 | 495 |
| 10 | Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma | Cancer Research | 2012 | 461 |
| 11 | Primary cervical cancer screening with human papillomavirus: End of study results from the ATHENA study using HPV as the first-line screening test | Gynecologic Oncology | 2015 | 442 |
| 12 | COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status | JCI Insight | 2020 | 412 |
| 13 | Oxidation of polyethylene glycols by alcohol dehydrogenase | Biochemical Pharmacology | 1989 | 388 |
| 14 | A Pilot Study of A Thiazolidinedione, Troglitazone, in Nonalcoholic Steatohepatitis | American Journal of Gastroenterology | 2001 | 352 |
| 15 | The host immune response in respiratory virus infection: balancing virus clearance and immunopathology | Seminars in Immunopathology | 2016 | 345 |
| 16 | Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53 | Nature | 2016 | 335 |
| 17 | A Laboratory-Developed TaqMan Array Card for Simultaneous Detection of 19 Enteropathogens | Journal of Clinical Microbiology | 2013 | 318 |
| 18 | Functional characterization of the dural sinuses as a neuroimmune interface | Cell | 2021 | 299 |
| 19 | RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation | Blood | 2003 | 293 |
| 20 | Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology | American Journal of Surgical Pathology | 2018 | 289 |
| 21 | Papillomavirus E6 oncoproteins | Virology | 2013 | 279 |
| 22 | Expression Patterns and Post-translational Modifications Associated with Mammalian Histone H3 Variants | Journal of Biological Chemistry | 2006 | 278 |
| 23 | The HLA-A*0201-Restricted H-Y Antigen Contains a Posttranslationally Modified Cysteine That Significantly Affects T Cell Recognition | Immunity | 1997 | 275 |
| 24 | Organismal Differences in Post-translational Modifications in Histones H3 and H4 | Journal of Biological Chemistry | 2007 | 267 |
| 25 | Malignancy Risk for Fine-Needle Aspiration of Thyroid Lesions According to The Bethesda System for Reporting Thyroid Cytopathology | American Journal of Clinical Pathology | 2010 | 263 |
| 26 | Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study | Lancet Infectious Diseases, The | 2014 | 263 |
| 27 | Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma | JCI Insight | 2017 | 257 |
| 28 | Interobserver Reproducibility of the Nottingham Modification of the Bloom and Richardson Histologic Grading Scheme for Infiltrating Ductal Carcinoma | American Journal of Clinical Pathology | 1995 | 248 |
| 29 | Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion | Nature | 2013 | 239 |
| 30 | Evaluation of Silica Resins for Direct and Efficient Extraction of DNA from Complex Biological Matrices in a Miniaturized Format | Analytical Biochemistry | 2000 | 236 |
| 31 | Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons | Nature Immunology | 2020 | 225 |
| 32 | Rat liver insulin mediator which stimulates pyruvate dehydrogenase phosphatase contains galactosamine and D-chiroinositol | Biochemical and Biophysical Research Communications | 1988 | 211 |
| 33 | Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials | Head and Neck | 2016 | 203 |
| 34 | Primary central nervous system post‐transplantation lymphoproliferative disorder | Cancer | 2010 | 202 |
| 35 | NUT Rearrangement in Undifferentiated Carcinomas of the Upper Aerodigestive Tract | American Journal of Surgical Pathology | 2008 | 201 |
| 36 | Suppression of Host Immune Response by the Core Protein of Hepatitis C Virus: Possible Implications for Hepatitis C Virus Persistence | Journal of Immunology | 1999 | 201 |
| 37 | Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720 | Journal of Biological Chemistry | 2005 | 198 |
| 38 | Phosphorylated Peptides Are Naturally Processed and Presented by Major Histocompatibility Complex Class I Molecules in Vivo | Journal of Experimental Medicine | 2000 | 192 |
| 39 | The Immunogenicity of a New Human Minor Histocompatibility Antigen Results from Differential Antigen Processing | Journal of Experimental Medicine | 2001 | 191 |
| 40 | Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients | Journal of Proteome Research | 2020 | 189 |
| 41 | Hepatocellular ballooning in NASH | Journal of Hepatology | 2010 | 185 |
| 42 | Macrophage Migration Inhibitory Factor Promotes Tumor Growth and Metastasis by Inducing Myeloid-Derived Suppressor Cells in the Tumor Microenvironment | Journal of Immunology | 2012 | 172 |
| 43 | Frequency-specific flow control in microfluidic circuits with passive elastomeric features | Nature Physics | 2009 | 171 |
| 44 | Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy | Nature Genetics | 2006 | 169 |
| 45 | Phosphorylated ERM Is Responsible for Increased T Cell Polarization, Adhesion, and Migration in Patients with Systemic Lupus Erythematosus | Journal of Immunology | 2007 | 169 |
| 46 | Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 168 |
| 47 | Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins | Science | 2013 | 167 |
| 48 | Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation | Nature | 2016 | 165 |
| 49 | Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node | Journal of Experimental Medicine | 2005 | 163 |
| 50 | Banff Schema for Grading Pancreas Allograft Rejection: Working Proposal by a Multi-Disciplinary International Consensus Panel | American Journal of Transplantation | 2008 | 163 |
