| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for developing, translating, and validating a questionnaire in perioperative and pain medicine | Saudi Journal of Anaesthesia | 2017 | 805 |
| 2 | Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 786 |
| 3 | Local Anesthetics and the Inflammatory Response | Anesthesiology | 2000 | 615 |
| 4 | Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 609 |
| 5 | Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013 | JAMA Pediatrics | 2016 | 479 |
| 6 | The Role of the Perioperative Period in Recurrence After Cancer Surgery | Anesthesia and Analgesia | 2010 | 279 |
| 7 | Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar | British Journal of Anaesthesia | 2013 | 232 |
| 8 | Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice | Pharmacology Biochemistry and Behavior | 2012 | 223 |
| 9 | Role of voltage-gated calcium channels in ascending pain pathways | Brain Research Reviews | 2009 | 215 |
| 10 | Genetically targeted magnetic control of the nervous system | Nature Neuroscience | 2016 | 211 |
| 11 | Postconditioning with Isoflurane Reduced Ischemia-induced Brain Injury in Rats | Anesthesiology | 2008 | 180 |
| 12 | Tracheostomy: why, when, and how? | Respiratory Care | 2010 | 177 |
| 13 | General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain | Anesthesiology | 2011 | 164 |
| 14 | Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats | Neuropharmacology | 2011 | 160 |
| 15 | The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: The importance of free oxygen radicals and mitochondrial integrity | Neurobiology of Disease | 2012 | 156 |
| 16 | Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | The Lancet Global Health | 2016 | 147 |
| 17 | Preventive Analgesia by Local Anesthetics | Anesthesia and Analgesia | 2013 | 144 |
| 18 | Local Anesthetic Effects on Priming and Activation of Human Neutrophils | Anesthesiology | 2001 | 142 |
| 19 | Influence of Congenital Heart Disease on Mortality After Noncardiac Surgery in Hospitalized Children | Pediatrics | 2000 | 140 |
| 20 | Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017 | JAMA Pediatrics | 2019 | 140 |
| 21 | Perioperative Blood Transfusions and Delayed Wound Healing After Hip Replacement Surgery: Effects on Duration of Hospitalization | Anesthesia and Analgesia | 2005 | 134 |
| 22 | Sequential Phosphorylation Mediates Receptor- and Kinase-induced Inhibition of TREK-1 Background Potassium Channels | Journal of Biological Chemistry | 2005 | 133 |
| 23 | Development and validation of Arabic version of the Hospital Anxiety and Depression Scale | Saudi Journal of Anaesthesia | 2017 | 133 |
| 24 | Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung | American Journal of Physiology - Lung Cellular and Molecular Physiology | 1996 | 132 |
| 25 | The Technological Impact of COVID-19 on the Future of Education and Health Care Delivery | Pain Physician | 2020 | 131 |
| 26 | Functional and oxygen-metabolic photoacoustic microscopy of the awake mouse brain | NeuroImage | 2017 | 129 |
| 27 | Fiberoptic Intubation: An Overview and UpdateDiscussion | Respiratory Care | 2014 | 125 |
| 28 | Early Exposure to General Anesthesia Disturbs Mitochondrial Fission and Fusion in the Developing Rat Brain | Anesthesiology | 2013 | 122 |
| 29 | Cardiac Output Monitoring | Critical Care Medicine | 2015 | 120 |
| 30 | Isoflurane, but not Halothane, Induces Protection of Human Myocardium via Adenosine A1Receptors and Adenosine Triphosphate–sensitive Potassium Channels | Anesthesiology | 2000 | 119 |
| 31 | Naloxone reversal of buprenorphine-induced respiratory depression | Clinical Pharmacology and Therapeutics | 1989 | 116 |
| 32 | The Role of T-Type Calcium Channels in Epilepsy and Pain | Current Pharmaceutical Design | 2006 | 108 |
| 33 | Incidence and Risk Factors for Chronic Postoperative Opioid Use After Major Spine Surgery: A Cross-Sectional Study With Longitudinal Outcome | Anesthesia and Analgesia | 2018 | 107 |
| 34 | Poisoning with 4-Aminopyridine: Report of Three Cases | Clinical Toxicology | 1980 | 104 |
| 35 | Isoflurane Induces Learning Impairment That Is Mediated by Interleukin 1β in Rodents | PLoS ONE | 2012 | 102 |
| 36 | The Burden of Mental Disorders in the Eastern Mediterranean Region, 1990-2013 | PLoS ONE | 2017 | 102 |
| 37 | Enriched Environment Attenuates Surgery-Induced Impairment of Learning, Memory, and Neurogenesis Possibly by Preserving BDNF Expression | Molecular Neurobiology | 2016 | 100 |
| 38 | Chronic Intermittent Fasting Improves Cognitive Functions and Brain Structures in Mice | PLoS ONE | 2013 | 98 |
| 39 | Hydroxyethyl Starch | Anesthesia and Analgesia | 1997 | 96 |
| 40 | The Possible Immunosuppressive Effects of Perioperative Blood Transfusion in Cancer Patients | Anesthesiology | 1988 | 94 |
| 41 | eNOS-deficient mice show reduced pulmonary vascular proliferation and remodeling to chronic hypoxia | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2000 | 92 |
| 42 | Improving Analgesic Efficacy and Safety of Thoracic Paravertebral Block for Breast Surgery: A Mixed-Effects Meta-Analysis | Pain Physician | 2015 | 91 |
| 43 | Timing versus duration | Annals of the New York Academy of Sciences | 2010 | 90 |
| 44 | Angiotensin II and nitric oxide: a question of balance | Regulatory Peptides | 1999 | 88 |
| 45 | Time-dependent Inhibition of G Protein–coupled Receptor Signaling by Local Anesthetics | Anesthesiology | 2004 | 88 |
| 46 | The Role of Opioid Receptor Internalization and ??-Arrestins in the Development of Opioid Tolerance | Anesthesia and Analgesia | 2005 | 88 |
| 47 | Local anaesthetics inhibit signalling of human NMDA receptors recombinantly expressed in Xenopus laevis oocytes: role of protein kinase C | British Journal of Anaesthesia | 2006 | 85 |
| 48 | Pulmonary complications of cardiopulmonary bypass | Bailliere's Best Practice and Research in Clinical Anaesthesiology | 2015 | 85 |
| 49 | Spironolactone Reduced Arrhythmia and Maintained Magnesium Homeostasis in Patients With Congestive Heart Failure | Journal of Cardiac Failure | 2007 | 84 |
| 50 | Dexmedetomidine attenuates sepsis-associated inflammation and encephalopathy via central α2A adrenoceptor | Brain, Behavior, and Immunity | 2021 | 84 |
