| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Structural and functional features of central nervous system lymphatic vessels | Nature | 2015 | 3,173 |
| 3 | p21 in cancer: intricate networks and multiple activities | Nature Reviews Cancer | 2009 | 2,192 |
| 4 | Cell adhesion: integrating cytoskeletal dynamics and cellular tension | Nature Reviews Molecular Cell Biology | 2010 | 1,665 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 1,416 |
| 7 | Regulation of cadherin-mediated adhesion in morphogenesis | Nature Reviews Molecular Cell Biology | 2005 | 1,342 |
| 8 | STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration | BMJ Open | 2016 | 1,324 |
| 9 | Breast Cancer Screening for Women at Average Risk | JAMA - Journal of the American Medical Association | 2015 | 1,283 |
| 10 | New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata | Neuroscience | 1988 | 1,214 |
| 11 | The CRISPR tool kit for genome editing and beyond | Nature Communications | 2018 | 1,159 |
| 12 | The extracellular matrix in development and morphogenesis: A dynamic view | Developmental Biology | 2010 | 1,120 |
| 13 | Specificity in the projection patterns of accumbal core and shell in the rat | Neuroscience | 1991 | 1,105 |
| 14 | Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. | Circulation Research | 1988 | 1,030 |
| 15 | Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease | Nature Biotechnology | 2014 | 682 |
| 16 | Influenza virus neuraminidase inhibitors | Lancet, The | 2000 | 642 |
| 17 | Characterization of the Human Cysteinyl Leukotriene 2 Receptor | Journal of Biological Chemistry | 2000 | 574 |
| 18 | Wild-type microglia arrest pathology in a mouse model of Rett syndrome | Nature | 2012 | 547 |
| 19 | Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens | PLoS ONE | 2013 | 538 |
| 20 | Release of Adenosine from Ischemic Brain | Circulation Research | 1974 | 537 |
| 21 | The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. | Proceedings of the National Academy of Sciences of the United States of America | 1987 | 528 |
| 22 | Revisiting the Mechanisms of CNS Immune Privilege | Trends in Immunology | 2015 | 515 |
| 23 | Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. | Genes and Development | 1988 | 512 |
| 24 | Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour | Nature | 2016 | 507 |
| 25 | Longitudinal Gradients in Periarteriolar Oxygen Tension | Circulation Research | 1970 | 464 |
| 26 | Understanding the functions and relationships of the glymphatic system and meningeal lymphatics | Journal of Clinical Investigation | 2017 | 436 |
| 27 | Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery | Otolaryngology - Head and Neck Surgery | 2013 | 435 |
| 28 | Measuring Fast Dynamics in Solutions and Cells with a Laser Scanning Microscope | Biophysical Journal | 2005 | 428 |
| 29 | Pulmonary Complications of Obesity | American Journal of the Medical Sciences | 2001 | 427 |
| 30 | Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope | Biophysical Journal | 2008 | 422 |
| 31 | Cognitive Impairment in Patients with Obstructive Sleep Apnea and Associated Hypoxemia | Chest | 1986 | 418 |
| 32 | Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI | ELife | 2017 | 403 |
| 33 | Fates of the blastomeres of the 32-cell-stage Xenopus embryo | Developmental Biology | 1987 | 396 |
| 34 | Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 393 |
| 35 | Using Whole-Exome Sequencing to Identify Inherited Causes of Autism | Neuron | 2013 | 383 |
| 36 | Cross-bridge phosphorylation and regulation of latch state in smooth muscle | American Journal of Physiology - Cell Physiology | 1988 | 373 |
| 37 | Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders | European Journal of Medicinal Chemistry | 2017 | 365 |
| 38 | Laboratory mice born to wild mice have natural microbiota and model human immune responses | Science | 2019 | 360 |
| 39 | AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease | Hepatology | 2023 | 358 |
| 40 | Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury Among Children | JAMA Pediatrics | 2018 | 357 |
| 41 | Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation | Science | 1990 | 345 |
| 42 | A Mindfulness Course Decreases Burnout and Improves Well-Being among Healthcare Providers | International Journal of Psychiatry in Medicine | 2012 | 341 |
| 43 | Interaction of Focal Adhesion Kinase with Cytoskeletal Protein Talin | Journal of Biological Chemistry | 1995 | 340 |
| 44 | The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA selective subunits | Neuron | 1993 | 335 |
| 45 | Cryptosporidiosis: An Emerging, Highly Infectious Threat | Emerging Infectious Diseases | 1997 | 335 |
| 46 | PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex | Genes and Development | 2008 | 334 |
| 47 | Inhibition of pp125FAK in cultured fibroblasts results in apoptosis. | Journal of Cell Biology | 1996 | 332 |
| 48 | Motor neuron columnar fate imposed by sequential phases of Hox-c activity | Nature | 2003 | 327 |
| 49 | Functional characterization of the dural sinuses as a neuroimmune interface | Cell | 2021 | 299 |
| 50 | Growth and Health in Children With Moderate-to-Severe Cerebral Palsy | Pediatrics | 2006 | 297 |
