| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Nature Genetics | 2010 | 1.9K |
| Single-neuron responses in humans during execution and observation of actions | Current Biology | 2010 | 897 |
| GeneCards Version 3: the human gene integrator | Database: the Journal of Biological Databases and Curation | 2010 | 742 |
| Alternative splicing and evolution: diversification, exon definition and function | Nature Reviews Genetics | 2010 | 705 |
| New technology and health care costs--the case of robot-assisted surgery | New England Journal of Medicine | 2010 | 670 |
| Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome | Pain | 2010 | 643 |
| Induced fit, conformational selection and independent dynamic segments: an extended view of binding events | Trends in Biochemical Sciences | 2010 | 617 |
| Effects of tobacco smoke on immunity, inflammation and autoimmunity | Journal of Autoimmunity | 2010 | 591 |
| NCLX is an essential component of mitochondrial Na+/Ca2+ exchange | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 547 |
| Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis | Antimicrobial Agents and Chemotherapy | 2010 | 450 |
| Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case-control study | International Journal of Epidemiology | 2010 | 431 |
| Translation efficiency is determined by both codon bias and folding energy | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 388 |
| Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice | Autoimmunity Reviews | 2010 | 384 |
| Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients | Clinical Cancer Research | 2010 | 354 |
| Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D? | Annals of the Rheumatic Diseases | 2010 | 349 |
| Mechanisms determining the morphology of the peripheral ER | Cell | 2010 | 342 |
| Genetic counselling and testing in cardiomyopathies: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases | European Heart Journal | 2010 | 324 |
| Executive control deficits as a prodrome to falls in healthy older adults: a prospective study linking thinking, walking, and falling | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2010 | 313 |
| Colchicine poisoning: the dark side of an ancient drug | Clinical Toxicology | 2010 | 305 |
| The genome-wide structure of the Jewish people | Nature | 2010 | 295 |
| Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism | Molecular Systems Biology | 2010 | 287 |
| Sub-angstrom modeling of complexes between flexible peptides and globular proteins | Proteins: Structure, Function and Bioinformatics | 2010 | 273 |
| Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group | Blood | 2010 | 265 |
| European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies | Annals of the Rheumatic Diseases | 2010 | 245 |
| Controversial issues in the management of pericardial diseases | Circulation | 2010 | 235 |
