| # | Title | Journal | Year | Citations |
|---|
| 1 | The Perseus computational platform for comprehensive analysis of (prote)omics data | Nature Methods | 2016 | 6,181 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Dementia prevention, intervention, and care | Lancet, The | 2017 | 4,228 |
| 4 | Environment dominates over host genetics in shaping human gut microbiota | Nature | 2018 | 1,958 |
| 5 | Personalized Nutrition by Prediction of Glycemic Responses | Cell | 2015 | 1,816 |
| 6 | Pre-eclampsia | Lancet, The | 2005 | 1,711 |
| 7 | Artificial sweeteners induce glucose intolerance by altering the gut microbiota | Nature | 2014 | 1,529 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 9 | Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target | American Journal of Gastroenterology | 2015 | 1,425 |
| 10 | Vaccine hesitancy: the next challenge in the fight against COVID-19 | European Journal of Epidemiology | 2020 | 1,290 |
| 11 | Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function | Trends in Pharmacological Sciences | 2006 | 1,237 |
| 12 | Serum MicroRNAs Are Promising Novel Biomarkers | PLoS ONE | 2008 | 1,203 |
| 13 | Summary and Recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus | Diabetes Care | 2007 | 1,201 |
| 14 | How proteins produce cellular membrane curvature | Nature Reviews Molecular Cell Biology | 2006 | 1,130 |
| 15 | The human tumor microbiome is composed of tumor type–specific intracellular bacteria | Science | 2020 | 1,077 |
| 16 | Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine | Science | 2017 | 1,059 |
| 17 | STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD | Gastroenterology | 2021 | 1,054 |
| 18 | Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis | Cell | 2014 | 984 |
| 19 | Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial | Lancet, The | 2000 | 952 |
| 20 | Y chromosome sequence variation and the history of human populations | Nature Genetics | 2000 | 935 |
| 21 | Alternative splicing and evolution: diversification, exon definition and function | Nature Reviews Genetics | 2010 | 921 |
| 22 | Mechanics of membrane fusion | Nature Structural and Molecular Biology | 2008 | 853 |
| 23 | Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. | Journal of Experimental Medicine | 1992 | 796 |
| 24 | Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients | Science | 2021 | 784 |
| 25 | Effects of tobacco smoke on immunity, inflammation and autoimmunity | Journal of Autoimmunity | 2010 | 741 |
| 26 | Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner | Cell | 2019 | 718 |
| 27 | The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics | Nature Reviews Gastroenterology and Hepatology | 2021 | 701 |
| 28 | Long-Term Stabilizing Effect of Angiotensin-Converting Enzyme Inhibition on Plasma Creatinine and on Proteinuria in Normotensive Type II Diabetic Patients | Annals of Internal Medicine | 1993 | 695 |
| 29 | Macrophages: Development and Tissue Specialization | Annual Review of Immunology | 2015 | 687 |
| 30 | Comparison of UTCI to selected thermal indices | International Journal of Biometeorology | 2012 | 680 |
| 31 | Epidemiology of gestational diabetes mellitus and its association with Type 2 diabetes | Diabetic Medicine | 2004 | 669 |
| 32 | Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality—A review of recent evidence | Autoimmunity Reviews | 2013 | 655 |
| 33 | Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia | Lancet Rheumatology, The | 2020 | 652 |
| 34 | The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection | Journal of Internal Medicine | 1998 | 637 |
| 35 | Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics | Drug Development Research | 2020 | 636 |
| 36 | Periodontitis and cardiovascular diseases: Consensus report | Journal of Clinical Periodontology | 2020 | 636 |
| 37 | Thermal Comfort and the Heat Stress Indices | Industrial Health | 2006 | 625 |
| 38 | Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients | Annals of the Rheumatic Diseases | 2015 | 610 |
| 39 | European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020 | Journal of Pediatric Gastroenterology and Nutrition | 2020 | 601 |
| 40 | The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on peripheral circulation | Atherosclerosis | 2015 | 587 |
| 41 | Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations | Annals of Oncology | 2020 | 582 |
| 42 | Systematic Review and Meta-Analysis of the Efficacy of Appropriate Empiric Antibiotic Therapy for Sepsis | Antimicrobial Agents and Chemotherapy | 2010 | 578 |
| 43 | Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins | Science | 1996 | 576 |
| 44 | Association Between Fibrosis Stage and Outcomes of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis | Gastroenterology | 2020 | 575 |
| 45 | Chromatin organization marks exon-intron structure | Nature Structural and Molecular Biology | 2009 | 569 |
| 46 | Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease | European Journal of Neurology | 2003 | 566 |
| 47 | Oral, Capsulized, Frozen Fecal Microbiota Transplantation for RelapsingClostridium difficileInfection | JAMA - Journal of the American Medical Association | 2014 | 554 |
| 48 | Autoantibody explosion in systemic lupus erythematosus: More than 100 different antibodies found in SLE patients | Seminars in Arthritis and Rheumatism | 2004 | 549 |
| 49 | Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia | Blood | 2021 | 539 |
| 50 | Multidrug-Resistant Pseudomonas aeruginosa : Risk Factors and Clinical Impact | Antimicrobial Agents and Chemotherapy | 2006 | 527 |
