# | Title | Journal | Year | Citations |
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1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
3 | Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy | Nature Reviews Molecular Cell Biology | 2014 | 2,444 |
4 | Count-based differential expression analysis of RNA sequencing data using R and Bioconductor | Nature Protocols | 2013 | 1,124 |
5 | Small-sample estimation of negative binomial dispersion, with applications to SAGE data | Biostatistics | 2007 | 939 |
6 | Moderated statistical tests for assessing differences in tag abundance | Bioinformatics | 2007 | 777 |
7 | Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies | Nature Reviews Cancer | 2016 | 596 |
8 | BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis | Science | 2018 | 581 |
9 | Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells | Nature Immunology | 2017 | 504 |
10 | TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway | Science Signaling | 2016 | 453 |
11 | Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases | EMBO Journal | 2011 | 432 |
12 | XIAP discriminates between type I and type II FAS-induced apoptosis | Nature | 2009 | 421 |
13 | miR‐223: infection, inflammation and cancer | Journal of Internal Medicine | 2013 | 360 |
14 | Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 337 |
15 | Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 | EMBO Journal | 2020 | 330 |
16 | Structure-guided design of a selective BCL-XL inhibitor | Nature Chemical Biology | 2013 | 324 |
17 | The cis-Regulatory Atlas of the Mouse Immune System | Cell | 2019 | 315 |
18 | Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations | Genome Research | 2016 | 312 |
19 | A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii | Immunity | 2012 | 311 |
20 | How the Bcl-2 family of proteins interact to regulate apoptosis | Cell Research | 2006 | 301 |
21 | The cellular and molecular basis for malaria parasite invasion of the human red blood cell | Journal of Cell Biology | 2012 | 285 |
22 | NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5 | European Journal of Immunology | 2015 | 283 |
23 | Spatial omics and multiplexed imaging to explore cancer biology | Nature Methods | 2021 | 279 |
24 | Mcl-1 is essential for the survival of plasma cells | Nature Immunology | 2013 | 273 |
25 | NK Cell Maturation and Peripheral Homeostasis Is Associated with KLRG1 Up-Regulation | Journal of Immunology | 2007 | 272 |
26 | A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment | Cancer Research | 2018 | 269 |
27 | The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway | Nature Immunology | 2013 | 264 |
28 | The transcriptional landscape of αβ T cell differentiation | Nature Immunology | 2013 | 256 |
29 | Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria | Immunity | 2015 | 250 |
30 | Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes | PLoS Pathogens | 2015 | 246 |
31 | TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice | ELife | 2014 | 232 |
32 | SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition | Nature Structural and Molecular Biology | 2013 | 229 |
33 | Combined immune checkpoint blockade as a therapeutic strategy for BRCA1 -mutated breast cancer | Science Translational Medicine | 2017 | 227 |
34 | RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers | Nature Medicine | 2016 | 224 |
35 | Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 224 |
36 | Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development | Journal of Immunology | 2013 | 213 |
37 | Complementarity and redundancy of IL-22-producing innate lymphoid cells | Nature Immunology | 2016 | 211 |
38 | Mutations in RAB39B Cause X-Linked Intellectual Disability and Early-Onset Parkinson Disease with α-Synuclein Pathology | American Journal of Human Genetics | 2014 | 207 |
39 | A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients | Cancer Immunology Research | 2019 | 201 |
40 | Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities | Cell Death and Differentiation | 2021 | 197 |
41 | IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling | Nature Communications | 2013 | 193 |
42 | Germinal center B and follicular helper T cells: siblings, cousins or just good friends? | Nature Immunology | 2011 | 192 |
43 | Association between Naturally Acquired Antibodies to Erythrocyte‐Binding Antigens ofPlasmodium falciparumand Protection from Malaria and High‐Density Parasitemia | Clinical Infectious Diseases | 2010 | 184 |
44 | Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance | Blood | 2011 | 174 |
45 | Targeting JAK kinase in solid tumors: emerging opportunities and challenges | Oncogene | 2016 | 173 |
46 | A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast | EMBO Journal | 2021 | 170 |
47 | Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 166 |
48 | The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins | Journal of Cell Biology | 2009 | 164 |
49 | Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways | Cell | 2019 | 163 |
50 | The Architecture and Evolution of Cancer Neochromosomes | Cancer Cell | 2014 | 161 |