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Center for Structural and Cell Biology in Medicine
›
top-articles
Center for Structural and Cell Biology in Medicine
157
(top 1%)
papers
10.0K
(top 1%)
citations
49
(top 1%)
h
-index
99
(top 1%)
g
-index
167
all documents
11.1K
doc citations
1.8K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
Science
2020
2,527
2
Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
Antiviral Research
2018
542
3
From
SARS
to
MERS
: crystallographic studies on coronaviral proteases enable antiviral drug design
FEBS Journal
2014
537
4
α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
Journal of Medicinal Chemistry
2020
437
5
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1
Nature Medicine
2012
405
6
Structure and functionality in flavivirus NS-proteins: Perspectives for drug design
Antiviral Research
2010
289
7
Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor
Science
2016
285
8
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer
EMBO Journal
2006
241
9
The battle for chitin recognition in plant-microbe interactions
FEMS Microbiology Reviews
2015
238
10
Fungal effector Ecp6 outcompetes host immune receptor for chitin binding through intrachain LysM dimerization
ELife
2013
217
11
pH-dependent Conformational Flexibility of the SARS-CoV Main Proteinase (Mpro) Dimer: Molecular Dynamics Simulations and Multiple X-ray Structure Analyses
Journal of Molecular Biology
2005
175
12
p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PL
pro
via E3 ubiquitin ligase RCHY1
Proceedings of the National Academy of Sciences of the United States of America
2016
172
13
The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes
PLoS Pathogens
2009
156
14
Megahertz serial crystallography
Nature Communications
2018
147
15
Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI
Developmental Cell
2012
123
16
Microbiome manipulation by a soil-borne fungal plant pathogen using effector proteins
Nature Plants
2020
118
17
Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease
Antiviral Research
2011
112
18
A G-quadruplex-binding macrodomain within the “SARS-unique domain” is essential for the activity of the SARS-coronavirus replication–transcription complex
Virology
2015
112
19
Structural and Functional Characterization of Falcipain-2, a Hemoglobinase from the Malarial Parasite Plasmodium falciparum
Journal of Biological Chemistry
2006
109
20
Tolerance induction with T cell–dependent protein antigens induces regulatory sialylated IgGs
Journal of Allergy and Clinical Immunology
2012
107
21
Peptide–Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology
Journal of Medicinal Chemistry
2017
105
22
Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response
Cellular and Molecular Life Sciences
2013
99
23
The Translocated Salmonella Effector Proteins SseF and SseG Interact and Are Required To Establish an Intracellular Replication Niche
Infection and Immunity
2006
98
24
3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses
Journal of Virology
2013
91
25
Processing of the SARS-CoV pp1a/ab nsp7–10 region
Biochemical Journal
2020
90
26
Chlamydia pneumoniaedirectly interferes with HIF-1α stabilization in human host cells
Cellular Microbiology
2007
89
27
A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters
Chemistry and Biology
2008
79
28
Picornavirus non-structural proteins as targets for new anti-virals with broad activity
Antiviral Research
2011
76
29
Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3
Developmental Biology
2009
75
30
Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features
Antiviral Research
2014
74
31
Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity
Journal of Virology
2012
73
32
Molecular Insights into Vesicle Tethering at the Golgi by the Conserved Oligomeric Golgi (COG) Complex and the Golgin TATA Element Modulatory Factor (TMF)
Journal of Biological Chemistry
2013
72
33
Hypoxia-Inducible Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (HIF-1β): Is It a Rare Exception?
Molecular Medicine
2014
69
34
Identification of Novel Falcipain-2 Inhibitors as Potential Antimalarial Agents through Structure-Based Virtual Screening
Journal of Medicinal Chemistry
2009
68
35
Structure and Cleavage Specificity of the Chymotrypsin-Like Serine Protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Journal of Molecular Biology
2009
66
36
Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo
Proceedings of the National Academy of Sciences of the United States of America
2010
66
37
Sensitized Detection of Inhibitory Fragments and Iterative Development of Non‐Peptidic Protease Inhibitors by Dynamic Ligation Screening
Angewandte Chemie - International Edition
2008
64
38
RNA
‐virus proteases counteracting host innate immunity
FEBS Letters
2017
64
39
Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus NS2B–NS3 Protease
ChemMedChem
2013
63
40
Curcumin Decreases Survival of Hep3B Liver and MCF-7 Breast Cancer Cells
Strahlentherapie Und Onkologie
2011
62
41
Recent Advances in Neuraminidase Inhibitor Development as Anti‐influenza Drugs
ChemMedChem
2012
62
42
Exoerythrocytic Plasmodium Parasites Secrete a Cysteine Protease Inhibitor Involved in Sporozoite Invasion and Capable of Blocking Cell Death of Host Hepatocytes
PLoS Pathogens
2010
61
43
The Capsid Binder Vapendavir and the Novel Protease Inhibitor SG85 Inhibit Enterovirus 71 Replication
Antimicrobial Agents and Chemotherapy
2014
60
44
Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode
Protein and Cell
2010
58
45
Antiviral strategies to control calicivirus infections
Antiviral Research
2010
55
46
Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination
Structure
2015
55
47
Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport
Cells
2018
55
48
Protein crystallization in living cells
Biological Chemistry
2018
55
49
Multiple Rieske proteins in prokaryotes: Where and why?
Biochimica Et Biophysica Acta - Bioenergetics
2005
54
50
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68
Antimicrobial Agents and Chemotherapy
2015
54
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