| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards | Nature Communications | 2016 | 2,076 |
| 3 | Role of Macrophage Targeting in the Antitumor Activity of Trabectedin | Cancer Cell | 2013 | 721 |
| 4 | Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation | Seminars in Cancer Biology | 2017 | 414 |
| 5 | Targeting folate receptor alpha for cancer treatment | Oncotarget | 2016 | 308 |
| 6 | CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo | Blood | 2012 | 296 |
| 7 | Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments | Annals of Oncology | 2015 | 241 |
| 8 | Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts | Cell Death and Disease | 2016 | 232 |
| 9 | Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects | Oncogene | 2013 | 204 |
| 10 | Challenges in Using Circulating miRNAs as Cancer Biomarkers | BioMed Research International | 2015 | 202 |
| 11 | miR-21: an oncomir on strike in prostate cancer | Molecular Cancer | 2010 | 189 |
| 12 | Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency | Nature Cell Biology | 2017 | 181 |
| 13 | TNF-Related Apoptosis-Inducing Ligand (TRAIL)–Armed Exosomes Deliver Proapoptotic Signals to Tumor Site | Clinical Cancer Research | 2016 | 158 |
| 14 | Breast cancer-secreted miR-939 downregulates VE-cadherin and destroys the barrier function of endothelial monolayers | Cancer Letters | 2017 | 131 |
| 15 | Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial | Lancet Oncology, The | 2012 | 130 |
| 16 | Cellular FLICE-inhibitory protein (c-FLIP) signalling: A key regulator of receptor-mediated apoptosis in physiologic context and in cancer | International Journal of Biochemistry and Cell Biology | 2010 | 129 |
| 17 | G-Quadruplex Structures in the Human Genome as Novel Therapeutic Targets | Molecules | 2013 | 125 |
| 18 | Mast Cell Targeting Hampers Prostate Adenocarcinoma Development but Promotes the Occurrence of Highly Malignant Neuroendocrine Cancers | Cancer Research | 2011 | 124 |
| 19 | Human Cutaneous Melanomas Lacking MITF and Melanocyte Differentiation Antigens Express a Functional Axl Receptor Kinase | Journal of Investigative Dermatology | 2011 | 122 |
| 20 | Tumor-extracellular matrix interactions: Identification of tools associated with breast cancer progression | Seminars in Cancer Biology | 2015 | 120 |
| 21 | Conversion to stem‐cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells | Molecular Oncology | 2016 | 120 |
| 22 | Consensus nomenclature for CD8+T cell phenotypes in cancer | OncoImmunology | 2015 | 119 |
| 23 | Circulating miR-378 in plasma: a reliable, haemolysis-independent biomarker for colorectal cancer | British Journal of Cancer | 2014 | 118 |
| 24 | IL-27 induces the expression of IDO and PD-L1 in human cancer cells | Oncotarget | 2015 | 115 |
| 25 | Enrichment of CD56dimKIR+CD57+ highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients | Nature Communications | 2014 | 109 |
| 26 | Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer | Oncogene | 2012 | 108 |
| 27 | A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants | British Journal of Cancer | 2010 | 107 |
| 28 | Head and neck cancer subtypes with biological and clinical relevance: Meta-analysis of gene-expression data | Oncotarget | 2015 | 103 |
| 29 | Senescent stroma promotes prostate cancer progression: The role of miR‐210 | Molecular Oncology | 2014 | 102 |
| 30 | Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production | Scientific Reports | 2017 | 102 |
| 31 | Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury | Journal of Cellular and Molecular Medicine | 2017 | 102 |
| 32 | Gold-Nanoparticle-Based Colorimetric Discrimination of Cancer-Related Point Mutations with Picomolar Sensitivity | ACS Nano | 2013 | 101 |
| 33 | Redox-Active Polymer Microcapsules for the Delivery of a Survivin-Specific siRNA in Prostate Cancer Cells | ACS Nano | 2011 | 99 |
| 34 | miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma | Oncotarget | 2014 | 98 |
| 35 | Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study | Lancet Oncology, The | 2016 | 97 |
| 36 | Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level | Journal of Hematology and Oncology | 2016 | 97 |
| 37 | MiR‐506 inhibits multiple targets in the epithelial‐to‐mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer | Journal of Pathology | 2015 | 94 |
| 38 | Bioinformatics tools for secretome analysis | Biochimica Et Biophysica Acta - Proteins and Proteomics | 2013 | 93 |
| 39 | Low-dose computed tomography for lung cancer screening: comparison of performance between annual and biennial screen | European Radiology | 2016 | 92 |
| 40 | Novel 1H-Pyrrolo[2,3-b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models | Journal of Medicinal Chemistry | 2013 | 91 |
| 41 | Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer | Breast Cancer Research and Treatment | 2011 | 88 |
| 42 | Role of MicroRNAs in Lung Cancer | Cancer Journal (Sudbury, Mass ) | 2012 | 85 |
| 43 | Complexity in the tumour microenvironment: Cancer associated fibroblast gene expression patterns identify both common and unique features of tumour-stroma crosstalk across cancer types | Seminars in Cancer Biology | 2015 | 85 |
| 44 | Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity | Cell Reports | 2016 | 84 |
| 45 | Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b | Oncotarget | 2016 | 84 |
| 46 | miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells | Biochemical Pharmacology | 2014 | 83 |
| 47 | Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis | Cancer Research | 2015 | 83 |
| 48 | Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study | Annals of Oncology | 2016 | 80 |
| 49 | miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis | Cancer Letters | 2017 | 80 |
| 50 | HER2 as a target for breast cancer therapy | Expert Opinion on Biological Therapy | 2010 | 78 |
