| # | Title | Journal | Year | Citations |
|---|
| 1 | Low-Dose Inhaled Corticosteroids and the Prevention of Death from Asthma | New England Journal of Medicine | 2000 | 1,039 |
| 2 | Disablement following stroke | Disability and Rehabilitation | 1999 | 438 |
| 3 | Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitis | Gastroenterology | 2001 | 429 |
| 4 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 5 | Cardiovascular Morbidity and Mortality in COPD | Chest | 2005 | 362 |
| 6 | A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis | Arthritis Research and Therapy | 2008 | 349 |
| 7 | Inhaled and Nasal Glucocorticoids and the Risks of Ocular Hypertension or Open-angle Glaucoma | JAMA - Journal of the American Medical Association | 1997 | 283 |
| 8 | Regular use of inhaled corticosteroids and the long term prevention of hospitalisation for asthma | Thorax | 2002 | 274 |
| 9 | Effectiveness of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2003 | 271 |
| 10 | Inhaled corticosteroids: Impact on asthma morbidity and mortality | Journal of Allergy and Clinical Immunology | 2001 | 265 |
| 11 | Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis | Lancet Neurology, The | 2005 | 254 |
| 12 | There’s No Place Like Home | Stroke | 2000 | 247 |
| 13 | Association of Selective and Conventional Nonsteroidal Antiinflammatory Drugs with Acute Renal Failure: A Population-based, Nested Case-Control Analysis | American Journal of Epidemiology | 2006 | 242 |
| 14 | Early supported discharge services for stroke patients: a meta-analysis of individual patients' data | Lancet, The | 2005 | 237 |
| 15 | Increased Risk of Childhood Asthma From Antibiotic Use in Early Life | Chest | 2007 | 237 |
| 16 | First-time use of newer oral contraceptives and the risk of venous thromboembolism | Contraception | 1997 | 192 |
| 17 | Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy | Cmaj | 2006 | 187 |
| 18 | A Longitudinal View of Apathy and Its Impact After Stroke | Stroke | 2009 | 176 |
| 19 | Association between antiphospholipid antibodies and recurrent fetal loss in women without autoimmune disease: a metaanalysis | Journal of Rheumatology | 2006 | 175 |
| 20 | Risk of ocular hypertension or open-angle glaucoma in elderly patients on oral glucocorticoids | Lancet, The | 1997 | 160 |
| 21 | Primer: administrative health databases in observational studies of drug effects—advantages and disadvantages | Nature Clinical Practice Rheumatology | 2007 | 159 |
| 22 | Treatment Completion and Costs of a Randomized Trial of Rifampin for 4 Months versus Isoniazid for 9 Months | American Journal of Respiratory and Critical Care Medicine | 2004 | 155 |
| 23 | Inhaled and Nasal Corticosteroid Use and the Risk of Fracture | American Journal of Respiratory and Critical Care Medicine | 2004 | 146 |
| 24 | Inhaled Corticosteroids and the Prevention of Readmission to Hospital for Asthma | American Journal of Respiratory and Critical Care Medicine | 1998 | 145 |
| 25 | Does home visiting prevent childhood injury? A systematic review of randomised controlled trials | BMJ: British Medical Journal | 1996 | 145 |
| 26 | Intake of Selenium in the Prevention of Prostate Cancer: a Systematic Review and Meta-analysis* | Cancer Causes and Control | 2005 | 135 |
| 27 | Early supported discharge services for stroke patients: a meta-analysis of individual patients' data | Lancet, The | 2005 | 132 |
| 28 | Statistical Treatment of Exacerbations in Therapeutic Trials of Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2006 | 129 |
| 29 | Effect of tramiprosate in patients with mild-to-moderate alzheimer's disease: Exploratory analyses of the MRI sub-group of the alphase study | Journal of Nutrition, Health and Aging | 2009 | 122 |
| 30 | ACE-inhibitor use and the long-term risk of renal failure in diabetes | Kidney International | 2006 | 117 |
| 31 | The relation between initial symptoms and signs and the prognosis of whiplash | European Spine Journal | 2001 | 114 |
| 32 | The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies | Cancer Epidemiology Biomarkers and Prevention | 2004 | 113 |
| 33 | Long-term functional benefits of selective dorsal rhizotomy for spastic cerebral palsy | Journal of Neurosurgery: Pediatrics | 2013 | 107 |
| 34 | Arthrography of the Shoulder: A Simple Fluoroscopically Guided Approach for Targeting the Rotator Cuff Interval | American Journal of Roentgenology | 2004 | 105 |
| 35 | Low-dose inhaled and nasal corticosteroid use and the risk of cataracts | European Respiratory Journal | 2006 | 105 |
| 36 | Low-dose inhaled corticosteroids and the risk of acute myocardial infarction in COPD | European Respiratory Journal | 2005 | 102 |
| 37 | Fine particulate air pollution and systemic autoimmune rheumatic disease in two Canadian provinces | Environmental Research | 2016 | 94 |
| 38 | Mammographically non-calcified ductal carcinoma in situ: sonographic features with pathological correlation in 35 patients | Clinical Radiology | 2009 | 93 |
| 39 | Inhaled steroids and mortality in COPD: bias from unaccounted immortal time | European Respiratory Journal | 2004 | 91 |
| 40 | Dynamic Sonography Evaluation of Shoulder Impingement Syndrome | American Journal of Roentgenology | 2006 | 91 |
| 41 | The Association Between Cigarette Smoking and Back Pain in Adults | Spine | 1999 | 89 |
| 42 | Response shift influenced estimates of change in health-related quality of life poststroke | Journal of Clinical Epidemiology | 2004 | 89 |
| 43 | Assessing methods for causality assessment of suspected adverse drug reactions | Journal of Clinical Epidemiology | 1989 | 88 |
| 44 | Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus | Nature Communications | 2016 | 78 |
| 45 | Change in quality of life of people with stroke over time: True change or response shift? | Quality of Life Research | 2005 | 74 |
| 46 | The Reading the Mind in the Eyes test: validation of a French version and exploration of cultural variations in a multi-ethnic city | Cognitive Neuropsychiatry | 2014 | 73 |
| 47 | Inhaled short acting beta agonist use in COPD and the risk of acute myocardial infarction | Thorax | 2003 | 72 |
| 48 | Tumour necrosis factor (TNF)α −308 G/G promoter polymorphism and TNFα levels correlate with a better response to adalimumab in patients with rheumatoid arthritis | Scandinavian Journal of Rheumatology | 2006 | 70 |
| 49 | Adverse Reproductive Outcomes among Women Exposed to Low Levels of Ionizing Radiation from Diagnostic Radiography for Adolescent Idiopathic Scoliosis | Epidemiology | 1998 | 68 |
| 50 | Hospitalization and Case-Fatality Rates for Stroke in Canada From 1982 Through 1991 | Stroke | 1996 | 67 |
