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Top Articles

#TitleJournalYearCitations
1Camelid and shark single domain antibodies: structural features and therapeutic potentialCurrent Opinion in Structural Biology2017165
2Structural insights and biomedical potential of IgNAR scaffolds from sharksMAbs2015102
3Therapeutic antibody engineering by high efficiency cell screeningFEBS Letters201495
4The Many Faces of FKBP51Biomolecules201979
5Shark Attack: High affinity binding proteins derived from shark vNAR domains by stepwise in vitro affinity maturationJournal of Biotechnology201474
6Antibody display technologies: selecting the cream of the cropBiological Chemistry202271
7Arranged Sevenfold: Structural Insights into the C-Terminal Oligomerization Domain of Human C4b-Binding ProteinJournal of Molecular Biology201369
8Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug ConjugatesJournal of Biological Chemistry201666
9A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast displayMAbs201564
10Single-domain antibodies for biomedical applicationsImmunopharmacology and Immunotoxicology201664
11Beyond antibody engineering: directed evolution of alternative binding scaffolds and enzymes using yeast surface displayMicrobial Cell Factories201858
12Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretionNature Communications202150
13Chemical Synthesis, Backbone Cyclization and Oxidative Folding of Cystine-knot Peptides — Promising Scaffolds for Applications in Drug DesignMolecules201243
14Engineering bispecific antibodies with defined chain pairingNew Biotechnology201743
15In Vivo Enzyme Immobilization by Inclusion Body DisplayApplied and Environmental Microbiology201040
16Recent progress in transglutaminase-mediated assembly of antibody-drug conjugatesAnalytical Biochemistry202038
17Engineering IgG-Like Bispecific Antibodies—An OverviewAntibodies201837
18The Hsp90 machinery facilitates the transport of diphtheria toxin into human cellsScientific Reports201736
19Host cell protein quantification by fourier transform mid infrared spectroscopy (FT‐MIR)Biotechnology and Bioengineering201334
20Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic bindersScientific Reports201734
21Generation of human bispecific common light chain antibodies by combining animal immunization and yeast displayProtein Engineering, Design and Selection201733
22At-line mid infrared spectroscopy for monitoring downstream processing unit operationsProcess Biochemistry201532
23Affinity Maturation of B7-H6 Translates into Enhanced NK Cell–Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 EngagementJournal of Immunology202132
24REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast CellsPLoS ONE201431
25Isolation of a pH-Sensitive IgNAR Variable Domain from a Yeast-Displayed, Histidine-Doped Master LibraryMarine Biotechnology201631
26A novel one-step approach for the construction of yeast surface display Fab antibody librariesMicrobial Cell Factories201831
27Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cellsCommunications Biology202231
28Yeast Surface Display in Combination with Fluorescence‐activated Cell Sorting Enables the Rapid Isolation of Antibody Fragments Derived from Immunized ChickensBiotechnology Journal201930
29Novel CH1:CL interfaces that enhance correct light chain pairing in heterodimeric bispecific antibodiesProtein Engineering, Design and Selection201729
30Development of a Univariate Membrane-Based Mid-Infrared Method for Protein Quantitation and Total Lipid Content Analysis of Biological SamplesJournal of Analytical Methods in Chemistry201428
31Generation of Potent Anti-HER1/2 Immunotoxins by Protein Ligation Using Split InteinsACS Chemical Biology201828
32A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well‐Defined Protein–Protein ConjugatesAngewandte Chemie - International Edition202028
33Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic ApproachACS Chemical Biology201527
34A simplified procedure for antibody engineering by yeast surface display: Coupling display levels and target binding by ribosomal skippingBiotechnology Journal201727
35Microbial transglutaminase for biotechnological and biomedical engineeringBiological Chemistry201927
36FACS-Based Functional Protein Screening via Microfluidic Co-encapsulation of Yeast Secretor and Mammalian Reporter CellsScientific Reports202027
37Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levelsAutophagy202127
38Oxidative Folding of Peptides with Cystine‐Knot Architectures: Kinetic Studies and Optimization of Folding ConditionsChemBioChem201326
39Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in PlasmaFrontiers in Immunology201926
40Targeting the Glucocorticoid Receptor Reduces Binge‐Like Drinking in High Drinking in the Dark (HDID‐1) MiceAlcoholism: Clinical and Experimental Research202026
41Carotenoids in Human Skin In Vivo: Antioxidant and Photo-Protectant Role against External and Internal StressorsAntioxidants202226
42Facile generation of antibody heavy and light chain diversities for yeast surface display by Golden Gate CloningBiological Chemistry201924
43From cell line development to the formulated drug product: The art of manufacturing therapeutic monoclonal antibodiesInternational Journal of Pharmaceutics202124
44Feasibility study of semi‐selective protein precipitation with salt‐tolerant copolymers for industrial purification of therapeutic antibodiesBiotechnology and Bioengineering201323
45Intein mediated high throughput screening for bispecific antibodiesMAbs202023
46Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody ArchitectureFrontiers in Immunology202123
47DNA Libraries for the Construction of Phage Libraries: Statistical and Structural Requirements and Synthetic MethodsMolecules201122
48A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeastNucleic Acids Research201922
49Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platformMAbs202022
50Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assemblyNature Communications202020