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Institute for Organic Chemistry and Biochemistry
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top-articles
Institute for Organic Chemistry and Biochemistry
111
(top 1%)
papers
2.2K
(top 1%)
citations
27
(top 1%)
h
-index
42
(top 1%)
g
-index
118
all documents
2.6K
doc citations
616
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Camelid and shark single domain antibodies: structural features and therapeutic potential
Current Opinion in Structural Biology
2017
165
2
Structural insights and biomedical potential of IgNAR scaffolds from sharks
MAbs
2015
102
3
Therapeutic antibody engineering by high efficiency cell screening
FEBS Letters
2014
95
4
The Many Faces of FKBP51
Biomolecules
2019
79
5
Shark Attack: High affinity binding proteins derived from shark vNAR domains by stepwise in vitro affinity maturation
Journal of Biotechnology
2014
74
6
Antibody display technologies: selecting the cream of the crop
Biological Chemistry
2022
71
7
Arranged Sevenfold: Structural Insights into the C-Terminal Oligomerization Domain of Human C4b-Binding Protein
Journal of Molecular Biology
2013
69
8
Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates
Journal of Biological Chemistry
2016
66
9
A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast display
MAbs
2015
64
10
Single-domain antibodies for biomedical applications
Immunopharmacology and Immunotoxicology
2016
64
11
Beyond antibody engineering: directed evolution of alternative binding scaffolds and enzymes using yeast surface display
Microbial Cell Factories
2018
58
12
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion
Nature Communications
2021
50
13
Chemical Synthesis, Backbone Cyclization and Oxidative Folding of Cystine-knot Peptides — Promising Scaffolds for Applications in Drug Design
Molecules
2012
43
14
Engineering bispecific antibodies with defined chain pairing
New Biotechnology
2017
43
15
In Vivo Enzyme Immobilization by Inclusion Body Display
Applied and Environmental Microbiology
2010
40
16
Recent progress in transglutaminase-mediated assembly of antibody-drug conjugates
Analytical Biochemistry
2020
38
17
Engineering IgG-Like Bispecific Antibodies—An Overview
Antibodies
2018
37
18
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells
Scientific Reports
2017
36
19
Host cell protein quantification by fourier transform mid infrared spectroscopy (FT‐MIR)
Biotechnology and Bioengineering
2013
34
20
Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders
Scientific Reports
2017
34
21
Generation of human bispecific common light chain antibodies by combining animal immunization and yeast display
Protein Engineering, Design and Selection
2017
33
22
At-line mid infrared spectroscopy for monitoring downstream processing unit operations
Process Biochemistry
2015
32
23
Affinity Maturation of B7-H6 Translates into Enhanced NK Cell–Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement
Journal of Immunology
2021
32
24
REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells
PLoS ONE
2014
31
25
Isolation of a pH-Sensitive IgNAR Variable Domain from a Yeast-Displayed, Histidine-Doped Master Library
Marine Biotechnology
2016
31
26
A novel one-step approach for the construction of yeast surface display Fab antibody libraries
Microbial Cell Factories
2018
31
27
Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells
Communications Biology
2022
31
28
Yeast Surface Display in Combination with Fluorescence‐activated Cell Sorting Enables the Rapid Isolation of Antibody Fragments Derived from Immunized Chickens
Biotechnology Journal
2019
30
29
Novel CH1:CL interfaces that enhance correct light chain pairing in heterodimeric bispecific antibodies
Protein Engineering, Design and Selection
2017
29
30
Development of a Univariate Membrane-Based Mid-Infrared Method for Protein Quantitation and Total Lipid Content Analysis of Biological Samples
Journal of Analytical Methods in Chemistry
2014
28
31
Generation of Potent Anti-HER1/2 Immunotoxins by Protein Ligation Using Split Inteins
ACS Chemical Biology
2018
28
32
A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well‐Defined Protein–Protein Conjugates
Angewandte Chemie - International Edition
2020
28
33
Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach
ACS Chemical Biology
2015
27
34
A simplified procedure for antibody engineering by yeast surface display: Coupling display levels and target binding by ribosomal skipping
Biotechnology Journal
2017
27
35
Microbial transglutaminase for biotechnological and biomedical engineering
Biological Chemistry
2019
27
36
FACS-Based Functional Protein Screening via Microfluidic Co-encapsulation of Yeast Secretor and Mammalian Reporter Cells
Scientific Reports
2020
27
37
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels
Autophagy
2021
27
38
Oxidative Folding of Peptides with Cystine‐Knot Architectures: Kinetic Studies and Optimization of Folding Conditions
ChemBioChem
2013
26
39
Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma
Frontiers in Immunology
2019
26
40
Targeting the Glucocorticoid Receptor Reduces Binge‐Like Drinking in High Drinking in the Dark (HDID‐1) Mice
Alcoholism: Clinical and Experimental Research
2020
26
41
Carotenoids in Human Skin In Vivo: Antioxidant and Photo-Protectant Role against External and Internal Stressors
Antioxidants
2022
26
42
Facile generation of antibody heavy and light chain diversities for yeast surface display by Golden Gate Cloning
Biological Chemistry
2019
24
43
From cell line development to the formulated drug product: The art of manufacturing therapeutic monoclonal antibodies
International Journal of Pharmaceutics
2021
24
44
Feasibility study of semi‐selective protein precipitation with salt‐tolerant copolymers for industrial purification of therapeutic antibodies
Biotechnology and Bioengineering
2013
23
45
Intein mediated high throughput screening for bispecific antibodies
MAbs
2020
23
46
Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture
Frontiers in Immunology
2021
23
47
DNA Libraries for the Construction of Phage Libraries: Statistical and Structural Requirements and Synthetic Methods
Molecules
2011
22
48
A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeast
Nucleic Acids Research
2019
22
49
Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform
MAbs
2020
22
50
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly
Nature Communications
2020
20
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