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Top Articles

#TitleJournalYearCitations
1Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian CellsScience20141,164
2Comparative Analysis of Single-Cell RNA Sequencing MethodsMolecular Cell20171,131
3CTCF-promoted RNA polymerase II pausing links DNA methylation to splicingNature2011853
4Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation EmbryosCell2016830
5Tn5 transposase and tagmentation procedures for massively scaled sequencing projectsGenome Research2014692
6Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In VivoCancer Cell2014272
7Sequentially acting Sox transcription factors in neural lineage developmentGenes and Development2011263
8Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profilingNature Communications2016246
9α-Synuclein–Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine NeuronsScience Translational Medicine2012221
10Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s DiseaseCell Stem Cell2017215
11Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulationNature Reviews Genetics2015174
12Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cellsExperimental Cell Research2003146
13BMP Signaling and Its pSMAD1/5 Target Genes Differentially Regulate Hair Follicle Stem Cell LineagesCell Stem Cell2014145
14Sox6 and Otx2 Control the Specification of Substantia Nigra and Ventral Tegmental Area Dopamine NeuronsCell Reports2014139
15NURR1 Mutations in cases of schizophrenia and manic-depressive disorderAmerican Journal of Medical Genetics Part A2000137
16Mechanistic Differences in the Transcriptional Interpretation of Local and Long-Range Shh Morphogen SignalingDevelopmental Cell2012131
17Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal LineagesCell Stem Cell2017127
18Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiationGenome Research201693
19Sox2 Acts in a Dose-Dependent Fashion to Regulate Proliferation of Cortical ProgenitorsCell Reports201486
20Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotypeNature Immunology201676
21Activation of Neural and Pluripotent Stem Cell Signatures Correlates with Increased Malignancy in Human GliomaPLoS ONE201175
22SoxB1-driven transcriptional network underlies neural-specific interpretation of morphogen signalsProceedings of the National Academy of Sciences of the United States of America201356
23MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate NeurogenesisCell Reports201656
24Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppressionProceedings of the National Academy of Sciences of the United States of America201756
25Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene ExpressionJournal of Neuroscience201552
26Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant miceJournal of Physiology200450
27Modulation by Trace Amine-Associated Receptor 1 of Experimental Parkinsonism, l-DOPA Responsivity, and Glutamatergic NeurotransmissionJournal of Neuroscience201546
28Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous systemProceedings of the National Academy of Sciences of the United States of America201440
29The molecular dynamics of long noncoding RNA control of transcription in PTEN and its pseudogeneProceedings of the National Academy of Sciences of the United States of America201738
30A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neuronsNature Communications201835
31Efficient and Comprehensive Representation of Uniqueness for Next-Generation Sequencing by Minimum Unique Length AnalysesPLoS ONE201329
32Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cellsGenome Research201624
33Induction and expression of abnormal involuntary movements is related to the duration of dopaminergic stimulation in 6‐OHDA‐lesioned ratsEuropean Journal of Neuroscience201121
34scphaser: haplotype inference using single-cell RNA-seq dataBioinformatics201620
35ALS Model Glia Can Mediate Toxicity to Motor Neurons Derived from Human Embryonic Stem CellsCell Stem Cell200819
36An update on viral association of human cancersArchives of Virology201319
37Elevated levels of ZAC1 disrupt neurogenesis and promote rapid in vivo reprogrammingStem Cell Research201617
38Reply to Mohlin et al.: High levels of EPAS1 are closely associated with key features of low-risk neuroblastomaProceedings of the National Academy of Sciences of the United States of America20174
39Genomic Occupancy in Various Cellular Contexts and Potential Pioneer Factor Function of SOX220161
40Reply to Liu et al.: Yin and yang of PTEN regulationProceedings of the National Academy of Sciences of the United States of America20170