| # | Title | Journal | Year | Citations |
|---|
| 1 | In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro | Nature Protocols | 2007 | 3,638 |
| 2 | Molecular Genetics of Colorectal Cancer | Annual Review of Pathology: Mechanisms of Disease | 2011 | 1,424 |
| 3 | Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth | Nature | 2012 | 1,088 |
| 4 | Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer | Nature | 2014 | 811 |
| 5 | Human Cancer Syndromes: Clues to the Origin and Nature of Cancer | Science | 1997 | 528 |
| 6 | First-pass metabolism of cyclosporin by the gut | Lancet, The | 1991 | 403 |
| 7 | Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis | Immunity | 2014 | 265 |
| 8 | Gene transfer of Fas ligand induces tumor regression in vivo | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 247 |
| 9 | COMMD Proteins, a Novel Family of Structural and Functional Homologs of MURR1 | Journal of Biological Chemistry | 2005 | 246 |
| 10 | Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 235 |
| 11 | The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis | Cancer Research | 2008 | 226 |
| 12 | A Two-Component Regulatory System, CsrR-CsrS, Represses Expression of Three Streptococcus pyogenes Virulence Factors, Hyaluronic Acid Capsule, Streptolysin S, and Pyrogenic Exotoxin B | Infection and Immunity | 1999 | 221 |
| 13 | Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression | Journal of Medicinal Chemistry | 2018 | 204 |
| 14 | Expression of human HPRT mRNA in brains of mice infected with a recombinant herpes simplex virus-1 vector | Gene | 1989 | 134 |
| 15 | Constitutive activation of the Wnt signaling pathway byCTNNB1 (?-catenin) mutations in a subset of human lung adenocarcinoma | Genes Chromosomes and Cancer | 2001 | 122 |
| 16 | Quantitative Proteomic Profiling of Prostate Cancer Reveals a Role for miR-128 in Prostate Cancer | Molecular and Cellular Proteomics | 2010 | 113 |
| 17 | Effects of hepatic arterial yttrium 90 glass microspheres in dogs | Cancer | 1988 | 96 |
| 18 | Surgical resection following radiation therapy with concurrent gemcitabine in patients with previously unresectable adenocarcinoma of the pancreas | Journal of Gastrointestinal Surgery | 2003 | 91 |
| 19 | Imaging of Renal Cancer Using Positron Emission Tomography with 2-Deoxy-2-(18F)-Fluoro-D-Glucose: Pilot Animal and Human Studies | Journal of Urology | 1991 | 73 |
| 20 | Mouse Brca1: localization, sequence analysis and identification of evolutionarily conserved domains | Human Molecular Genetics | 1995 | 72 |
| 21 | Function of Focal Adhesion Kinase Scaffolding to Mediate Endophilin A2 Phosphorylation Promotes Epithelial-Mesenchymal Transition and Mammary Cancer Stem Cell Activities in Vivo | Journal of Biological Chemistry | 2013 | 72 |
| 22 | The promise of cancer genetics | Lancet, The | 1998 | 68 |
| 23 | Symptomatic Bradyarrhythmias in the Adult: Natural History Following Ventricular Pacemaker Implantation | PACE - Pacing and Clinical Electrophysiology | 1982 | 63 |
| 24 | Diagnosing fibrotic lung disease: When is high‐resolution computed tomography sufficient to make a diagnosis of idiopathic pulmonary fibrosis? | Respirology | 2009 | 59 |
| 25 | Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin–proteasome pathway | Oncogene | 2010 | 53 |
| 26 | Differential leptin access into the brain — A hierarchical organization of hypothalamic leptin target sites? | Physiology and Behavior | 2008 | 51 |
| 27 | Maternal Cdx2 is dispensable for mouse development | Development (Cambridge) | 2012 | 51 |
| 28 | Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication | BMC Genomics | 2010 | 50 |
| 29 | Thiosulfate sulfurtransferase-like domain–containing 1 protein interacts with thioredoxin | Journal of Biological Chemistry | 2018 | 49 |
| 30 | A double-blind, randomized, placebo-controlled trial of prostaglandinE1 in liver transplantation | Hepatology | 1995 | 48 |
| 31 | Mammalian Lin-7 Stabilizes Polarity Protein Complexes | Journal of Biological Chemistry | 2006 | 45 |
| 32 | Cyclic Nucleotide Regulation of PAI-1 mRNA Stability | Journal of Biological Chemistry | 1999 | 42 |
| 33 | Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo | Scientific Reports | 2019 | 37 |
| 34 | Sequential expression of cell surface C3bi receptors during neutrophil locomotion | Journal of Cellular Physiology | 1989 | 35 |
| 35 | Glucaric acid as an indicator of use of enzyme-inducing drugs | Clinical Pharmacology and Therapeutics | 1974 | 32 |
| 36 | CD28 and staphylococcal enterotoxins synergize to induce MHC-independent T-cell proliferation | Cellular Immunology | 1992 | 31 |
| 37 | A Combined Paging Alert and Web-Based Instrument Alters Clinician Behavior and Shortens Hospital Length of Stay in Acute Pancreatitis | American Journal of Gastroenterology | 2014 | 30 |
| 38 | DCC: Is there a connection between tumorigenesis and cell guidance molecules? | Biochimica Et Biophysica Acta: Reviews on Cancer | 1996 | 28 |
| 39 | Caveolar Structure and Protein Sorting Are Maintained in NIH 3T3 Cells Independent of Glycosphingolipid Depletion | Archives of Biochemistry and Biophysics | 2000 | 28 |
| 40 | Familial occurrence of intracranial arterial occlusive disease (Moyamoya) in neurofibromatosis | Clinical Genetics | 1980 | 28 |
| 41 | Cultured adult rat jejunal explants as a model for studying regulation of CYP3A | Biochemical Pharmacology | 1993 | 21 |
| 42 | Increased JNK Phosphorylation and Oxidative Stress in Response to Increased Glucose Flux through Increased GLUT1 Expression in Rat Retinal Endothelial Cells | | 2005 | 19 |
| 43 | The Syndrome of Hypertension, Hyperreninemia and Secondary Aldosteronism Associated with Renal Juxtaglomerular Cell Tumor (primary Reninism) | Journal of Urology | 1973 | 18 |
| 44 | Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis | Laboratory Investigation | 2019 | 18 |
| 45 | An immunohistochemical approach to detect oncogenic CTNNB1 mutations in primary neoplastic tissues | Laboratory Investigation | 2019 | 18 |
| 46 | Herpes Simplex Virus-Mediated Human Hypoxanthine-Guanine Phosphoribosyltransferase Gene Transfer into Neuronal Cells | Molecular and Cellular Biology | 1988 | 18 |
| 47 | Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting | American Heart Journal | 1996 | 17 |
| 48 | Combination Gene Delivery of the Cell Cycle Inhibitor p27 with Thymidine Kinase Enhances Prodrug Cytotoxicity | Journal of Virology | 1998 | 14 |
| 49 | Biliary NIK promotes ductular reaction and liver injury and fibrosis in mice | Nature Communications | 2022 | 12 |
| 50 | Familial breast cancer. Approaching the isolation of a susceptibility gene | Cancer | 1994 | 11 |
