# | Title | Journal | Year | Citations |
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1 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
2 | Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases | Nature | 2019 | 1,638 |
3 | Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma | Nature Medicine | 2007 | 1,177 |
4 | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms | Leukemia | 2022 | 1,023 |
5 | An integrative genomics approach to infer causal associations between gene expression and disease | Nature Genetics | 2005 | 967 |
6 | Mapping the Genetic Architecture of Gene Expression in Human Liver | PLoS Biology | 2008 | 872 |
7 | American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants | Genetics in Medicine | 2011 | 794 |
8 | Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice | Cancer Research | 2009 | 699 |
9 | Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma | Nature | 2014 | 547 |
10 | Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma | PLoS Medicine | 2008 | 499 |
11 | Antibody-based protection against HIV infection by vectored immunoprophylaxis | Nature | 2012 | 488 |
12 | The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR | Nature | 2014 | 485 |
13 | DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study | Genetics in Medicine | 2012 | 471 |
14 | The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans | Science | 2011 | 441 |
15 | Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight | PLoS Genetics | 2006 | 419 |
16 | CLSI Methods Development and Standardization Working Group Best Practices for Evaluation of Antimicrobial Susceptibility Tests | Journal of Clinical Microbiology | 2018 | 372 |
17 | The ageing immune system: is it ever too old to become young again? | Nature Reviews Immunology | 2009 | 362 |
18 | Clinical experiences with systemically administered siRNA-based therapeutics in cancer | Nature Reviews Drug Discovery | 2015 | 349 |
19 | Weighted gene coexpression network analysis strategies applied to mouse weight | Mammalian Genome | 2007 | 337 |
20 | Immunological Consequences of Intestinal Fungal Dysbiosis | Cell Host and Microbe | 2016 | 329 |
21 | Biology of EWS/ETS fusions in Ewing's family tumors | Oncogene | 2001 | 308 |
22 | ARNT-Deficient Mice and Placental Differentiation | Developmental Biology | 1997 | 300 |
23 | Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain | PLoS Medicine | 2006 | 298 |
24 | Progression to the G1b Phase of the Cell Cycle Is Required for Completion of Human Immunodeficiency Virus Type 1 Reverse Transcription in T Cells | Journal of Virology | 1998 | 297 |
25 | Long Noncoding RNA MALAT-1 is a New Potential Therapeutic Target for Castration Resistant Prostate Cancer | Journal of Urology | 2013 | 292 |
26 | Salivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer | Gastroenterology | 2010 | 275 |
27 | Probabilistic fine-mapping of transcriptome-wide association studies | Nature Genetics | 2019 | 275 |
28 | NUCLEAR RECEPTORS IN MACROPHAGE BIOLOGY: At the Crossroads of Lipid Metabolism and Inflammation | Annual Review of Cell and Developmental Biology | 2004 | 262 |
29 | A role for the apoptosis inhibitory factor AIM/Spα/Api6 in atherosclerosis development | Cell Metabolism | 2005 | 257 |
30 | Liver X Receptor Signaling Pathways and Atherosclerosis | Arteriosclerosis, Thrombosis, and Vascular Biology | 2010 | 257 |
31 | Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits | American Journal of Human Genetics | 2017 | 248 |
32 | Correlation of hypointensities in susceptibility-weighted images to tissue histology in dementia patients with cerebral amyloid angiopathy: a postmortem MRI study | Acta Neuropathologica | 2010 | 246 |
33 | IFATS Collection: Human Adipose Tissue-Derived Stem Cells Induce Angiogenesis and Nerve Sprouting Following Myocardial Infarction, in Conjunction with Potent Preservation of Cardiac Function | Stem Cells | 2009 | 245 |
34 | Physiological Osmotic Induction of Leptospira interrogans Adhesion: LigA and LigB Bind Extracellular Matrix Proteins and Fibrinogen | Infection and Immunity | 2007 | 244 |
35 | When Is Hub Gene Selection Better than Standard Meta-Analysis? | PLoS ONE | 2013 | 243 |
36 | Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells | Nature Protocols | 2012 | 233 |
37 | Tumour–induced immune modulation of sentinel lymph nodes | Nature Reviews Immunology | 2006 | 230 |
38 | Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 Diabetes | Diabetes | 2009 | 222 |
39 | Discovery and Preclinical Validation of Salivary Transcriptomic and Proteomic Biomarkers for the Non-Invasive Detection of Breast Cancer | PLoS ONE | 2010 | 222 |
40 | Exome Sequencing in the Clinical Diagnosis of Sporadic or Familial Cerebellar Ataxia | JAMA Neurology | 2014 | 211 |
41 | Galectin-3 Induces Death of Candida Species Expressing Specific β-1,2-Linked Mannans | Journal of Immunology | 2006 | 208 |
42 | First Report of Ceftazidime-Avibactam Resistance in a KPC-3-Expressing Klebsiella pneumoniae Isolate | Antimicrobial Agents and Chemotherapy | 2015 | 207 |
43 | CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA | Genome Biology | 2017 | 204 |
44 | Intestinal Microbes Affect Phenotypes and Functions of Invariant Natural Killer T Cells in Mice | Gastroenterology | 2012 | 197 |
45 | Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway | PLoS ONE | 2011 | 196 |
46 | Recruitment of the NCoA/SRC-1/p160 Family of Transcriptional Coactivators by the Aryl Hydrocarbon Receptor/Aryl Hydrocarbon Receptor Nuclear Translocator Complex | Molecular and Cellular Biology | 2002 | 194 |
47 | DNA-microarray analysis of brain cancer: molecular classification for therapy | Nature Reviews Neuroscience | 2004 | 189 |
48 | Reduction in the Developmental Potential of Intrathymic T Cell Progenitors with Age | Journal of Immunology | 2004 | 188 |
49 | Comprehensive Assessment and Standardization of Solid Phase Multiplex-Bead Arrays for the Detection of Antibodies to HLA | American Journal of Transplantation | 2013 | 187 |
50 | Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism | ISME Journal | 2014 | 182 |