# | Title | Journal | Year | Citations |
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1 | Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials | Lancet, The | 2016 | 5,331 |
2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
3 | DNA methylation age of human tissues and cell types | Genome Biology | 2013 | 4,566 |
4 | Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response | Science | 2006 | 3,367 |
5 | Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis | Nature Medicine | 2013 | 3,355 |
6 | Strong Association of De Novo Copy Number Mutations with Autism | Science | 2007 | 2,497 |
7 | Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning | Nature | 2008 | 2,039 |
8 | Reassessment of Exosome Composition | Cell | 2019 | 1,786 |
9 | Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases | Nature | 2019 | 1,638 |
10 | Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis | JAMA - Journal of the American Medical Association | 2016 | 1,617 |
11 | OsiriX: An Open-Source Software for Navigating in Multidimensional DICOM Images | Journal of Digital Imaging | 2004 | 1,560 |
12 | Advances in autism genetics: on the threshold of a new neurobiology | Nature Reviews Genetics | 2008 | 1,552 |
13 | An epigenetic biomarker of aging for lifespan and healthspan | Aging | 2018 | 1,552 |
14 | Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders | Nature Neuroscience | 2006 | 1,458 |
15 | Prolonged Grief Disorder: Psychometric Validation of Criteria Proposed for DSM-V and ICD-11 | PLoS Medicine | 2009 | 1,320 |
16 | The Response of CD24 −/low /CD44 + Breast Cancer–Initiating Cells to Radiation | Journal of the National Cancer Institute | 2006 | 1,225 |
17 | Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma | Nature Medicine | 2007 | 1,177 |
18 | Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism | Neuron | 2011 | 1,146 |
19 | DNA methylation GrimAge strongly predicts lifespan and healthspan | Aging | 2019 | 1,128 |
20 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
21 | Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults | Nature | 2018 | 1,074 |
22 | Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism | Cell | 2013 | 948 |
23 | Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study | Lancet, The | 2020 | 931 |
24 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
25 | DNA methylation age of blood predicts all-cause mortality in later life | Genome Biology | 2015 | 928 |
26 | Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma | Nature Medicine | 2015 | 927 |
27 | Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomised clinical trials | BMJ: British Medical Journal | 2004 | 899 |
28 | Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons | Nature Neuroscience | 2010 | 892 |
29 | Diversity of astrocyte functions and phenotypes in neural circuits | Nature Neuroscience | 2015 | 892 |
30 | Identification of erythroferrone as an erythroid regulator of iron metabolism | Nature Genetics | 2014 | 890 |
31 | Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis | Journal of Experimental Medicine | 2009 | 878 |
32 | Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap | Science | 2018 | 851 |
33 | Activity of the Dual Kinase Inhibitor Lapatinib (GW572016) against HER-2-Overexpressing and Trastuzumab-Treated Breast Cancer Cells | Cancer Research | 2006 | 846 |
34 | Clinical Exome Sequencing for Genetic Identification of Rare Mendelian Disorders | JAMA - Journal of the American Medical Association | 2014 | 842 |
35 | P2X receptors as cell-surface ATP sensors in health and disease | Nature | 2006 | 772 |
36 | STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury | Journal of Neuroscience | 2008 | 770 |
37 | BREATHING: Rhythmicity, Plasticity, Chemosensitivity | Annual Review of Neuroscience | 2003 | 759 |
38 | 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 759 |
39 | ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation | Cell Metabolism | 2005 | 754 |
40 | Functional organization of the transcriptome in human brain | Nature Neuroscience | 2008 | 743 |
41 | The Brain-Gut-Microbiome Axis | Cellular and Molecular Gastroenterology and Hepatology | 2018 | 735 |
42 | New mitochondrial DNA synthesis enables NLRP3 inflammasome activation | Nature | 2018 | 722 |
43 | Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice | Cancer Research | 2009 | 699 |
44 | The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data | Brain Imaging and Behavior | 2014 | 696 |
45 | Consensus Guidelines on the Testing and Clinical Management Issues Associated With HLA and Non-HLA Antibodies in Transplantation | Transplantation | 2013 | 679 |
46 | A living WHO guideline on drugs for covid-19 | BMJ, The | 2020 | 664 |
47 | Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain | Nature Neuroscience | 2014 | 663 |
48 | Gene Expression Profiling of Gliomas Strongly Predicts Survival | Cancer Research | 2004 | 659 |
49 | Quality of Life, Fertility Concerns, and Behavioral Health Outcomes in Younger Breast Cancer Survivors: A Systematic Review | Journal of the National Cancer Institute | 2012 | 659 |
50 | Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner | Cell Stem Cell | 2011 | 653 |