| # | Title | Journal | Year | Citations |
|---|
| 1 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 2 | Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction | Nature Genetics | 2009 | 709 |
| 3 | Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences | European Heart Journal | 2013 | 679 |
| 4 | The Generation R Study: design and cohort update 2017 | European Journal of Epidemiology | 2016 | 608 |
| 5 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
| 6 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 7 | B-Type Natriuretic Peptide and Prognosis in Heart Failure Patients With Preserved and Reduced Ejection Fraction | Journal of the American College of Cardiology | 2013 | 352 |
| 8 | Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study | Lancet Diabetes and Endocrinology,the | 2014 | 319 |
| 9 | The EPIC nutrient database project (ENDB): a first attempt to standardize nutrient databases across the 10 European countries participating in the EPIC study | European Journal of Clinical Nutrition | 2007 | 309 |
| 10 | Levels of ambient air pollution according to mode of transport: a systematic review | Lancet Public Health, The | 2017 | 232 |
| 11 | European Association of Preventive Cardiology (EAPC) and European Association of Cardiovascular Imaging (EACVI) joint position statement: recommendations for the indication and interpretation of cardiovascular imaging in the evaluation of the athlete’s heart | European Heart Journal | 2018 | 224 |
| 12 | Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study | Radiotherapy and Oncology | 2012 | 223 |
| 13 | Arterial Stiffness and Cerebral Small Vessel Disease | Stroke | 2012 | 208 |
| 14 | Lifestyle factors, cardiovascular disease and all-cause mortality in middle-aged and elderly women: a systematic review and meta-analysis | European Journal of Epidemiology | 2018 | 180 |
| 15 | Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO 2 Air Pollution Exposure | Environmental Health Perspectives | 2017 | 176 |
| 16 | Relationship between gut microbiota and circulating metabolites in population-based cohorts | Nature Communications | 2019 | 168 |
| 17 | Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits | American Journal of Human Genetics | 2017 | 131 |
| 18 | Chronotype: Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health | Advances in Nutrition | 2019 | 129 |
| 19 | The Development of the Older Persons and Informal Caregivers Survey Minimum DataSet (TOPICS-MDS): A Large-Scale Data Sharing Initiative | PLoS ONE | 2013 | 128 |
| 20 | Hit-And-Run enables efficient weight generation for simulation-based multiple criteria decision analysis | European Journal of Operational Research | 2013 | 122 |
| 21 | Gestational vitamin D deficiency and autism-related traits: the Generation R Study | Molecular Psychiatry | 2018 | 120 |
| 22 | Association of Insulin Resistance and Type 2 Diabetes With Gut Microbial Diversity | JAMA Network Open | 2021 | 119 |
| 23 | Bi-directional associations between child fussy eating and parents' pressure to eat: Who influences whom? | Physiology and Behavior | 2017 | 117 |
| 24 | Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam Study | European Journal of Epidemiology | 2017 | 111 |
| 25 | Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins | JAMA Oncology | 2018 | 109 |
| 26 | Genetic polymorphisms of GnRH and gonadotrophic hormone receptors affect the phenotype of polycystic ovary syndrome | Human Reproduction | 2009 | 108 |
| 27 | Reliability of Serum Metabolites over a Two-Year Period: A Targeted Metabolomic Approach in Fasting and Non-Fasting Samples from EPIC | PLoS ONE | 2015 | 107 |
| 28 | Ultrasound Measurements of Visceral and Subcutaneous Abdominal Thickness to Predict Abdominal Adiposity Among Older Men and Women | Obesity | 2010 | 103 |
| 29 | Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy | Human Brain Mapping | 2014 | 98 |
| 30 | Exploring strategies to operationalize cognitive reserve: A systematic review of reviews | Journal of Clinical and Experimental Neuropsychology | 2015 | 94 |
| 31 | Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer | Nature Communications | 2016 | 93 |
| 32 | Crepitus is a first indication of patellofemoral osteoarthritis (and not of tibiofemoral osteoarthritis) | Osteoarthritis and Cartilage | 2014 | 82 |
| 33 | Lifetime alcohol use and overall and cause-specific mortality in the European Prospective Investigation into Cancer and nutrition (EPIC) study | BMJ Open | 2014 | 81 |
| 34 | Genomic analysis of diet composition finds novel loci and associations with health and lifestyle | Molecular Psychiatry | 2021 | 79 |
| 35 | Genome-wide association study identifies 48 common genetic variants associated with handedness | Nature Human Behaviour | 2021 | 79 |
| 36 | Alteration of amino acid and biogenic amine metabolism in hepatobiliary cancers: Findings from a prospective cohort study | International Journal of Cancer | 2016 | 77 |
| 37 | Early life antibiotic use and the risk of asthma and asthma exacerbations in children | Pediatric Allergy and Immunology | 2017 | 77 |
| 38 | Uric acid in major depressive and anxiety disorders | Journal of Affective Disorders | 2018 | 75 |
| 39 | Premenopausal serum sex hormone levels in relation to breast cancer risk, overall and by hormone receptor status-Results from the EPIC cohort | International Journal of Cancer | 2014 | 71 |
| 40 | Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities | Stroke | 2020 | 71 |
| 41 | Risk of second primary malignancies in women with breast cancer: Results from the European prospective investigation into cancer and nutrition (EPIC) | International Journal of Cancer | 2015 | 70 |
| 42 | Evaluation of risk prediction updates from commercial genome-wide scans | Genetics in Medicine | 2009 | 69 |
| 43 | Skeletal muscle mass loss and dose‐limiting toxicities in metastatic colorectal cancer patients | Journal of Cachexia, Sarcopenia and Muscle | 2019 | 65 |
| 44 | Osteogenesis imperfecta in childhood: Prognosis for walking | Journal of Pediatrics | 2000 | 63 |
| 45 | Circulating prolactin and breast cancer risk among pre- and postmenopausal women in the EPIC cohort | Annals of Oncology | 2014 | 63 |
| 46 | Sleep and risk of parkinsonism and Parkinson’s disease: a population-based study | Brain | 2019 | 63 |
| 47 | Improvement of Risk Prediction by Genomic Profiling: Reclassification Measures Versus the Area Under the Receiver Operating Characteristic Curve | American Journal of Epidemiology | 2010 | 61 |
| 48 | The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: A systematic review | Nutrition, Metabolism and Cardiovascular Diseases | 2016 | 61 |
| 49 | Protein intake in early childhood and body composition at the age of 6 years: The Generation R Study | International Journal of Obesity | 2016 | 60 |
| 50 | Macronutrient composition and gestational weight gain: a systematic review | American Journal of Clinical Nutrition | 2016 | 57 |
