| # | Title | Journal | Year | Citations |
|---|
| 1 | On the road to cancer: aneuploidy and the mitotic checkpoint | Nature Reviews Cancer | 2005 | 1,046 |
| 2 | Symptom Prevalence in Patients with Incurable Cancer: A Systematic Review | Journal of Pain and Symptom Management | 2007 | 790 |
| 3 | Genome-wide cell-free DNA fragmentation in patients with cancer | Nature | 2019 | 764 |
| 4 | Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates | Science | 2009 | 491 |
| 5 | Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy | Nature Genetics | 2010 | 295 |
| 6 | Polo-Like Kinases: A Team in Control of the Division | Cell Cycle | 2006 | 276 |
| 7 | The chromosomal passenger complex: guiding Aurora-B through mitosis | Journal of Cell Biology | 2006 | 259 |
| 8 | Mechanisms of Centrosome Separation and Bipolar Spindle Assembly | Developmental Cell | 2010 | 195 |
| 9 | Cdc20 and Cks Direct the Spindle Checkpoint-Independent Destruction of Cyclin A | Molecular Cell | 2008 | 165 |
| 10 | Activation of nuclear factor-kappa B signalling promotes cellular senescence | Oncogene | 2011 | 158 |
| 11 | Checkpoint control and cancer | Oncogene | 2012 | 141 |
| 12 | Plasma Free Metanephrine Measurement Using Automated Online Solid-Phase Extraction HPLC–Tandem Mass Spectrometry | Clinical Chemistry | 2007 | 132 |
| 13 | Activation of FoxM1 during G2 Requires Cyclin A/Cdk-Dependent Relief of Autorepression by the FoxM1 N-Terminal Domain | Molecular and Cellular Biology | 2008 | 131 |
| 14 | Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia | Blood | 2009 | 124 |
| 15 | Interplay between VHL/HIF1α and Wnt/β-catenin pathways during colorectal tumorigenesis | Oncogene | 2006 | 103 |
| 16 | Are anxiety and depressed mood related to physical symptom burden? A study in hospitalized advanced cancer patients | Palliative Medicine | 2007 | 103 |
| 17 | To cell cycle, swing the APC/C | Biochimica Et Biophysica Acta: Reviews on Cancer | 2008 | 102 |
| 18 | Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cells | Journal of Cellular Physiology | 2011 | 100 |
| 19 | Moving towards dose individualization of tyrosine kinase inhibitors | Cancer Treatment Reviews | 2011 | 98 |
| 20 | Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy | Human Brain Mapping | 2014 | 98 |
| 21 | Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Thrombospondin-1–Mimetic Angiogenesis Inhibitor ABT-510 in Patients With Advanced Cancer | Journal of Clinical Oncology | 2005 | 96 |
| 22 | The Chromosomal Passenger Complex Controls Spindle Checkpoint Function Independent from Its Role in Correcting Microtubule–Kinetochore Interactions | Molecular Biology of the Cell | 2007 | 88 |
| 23 | Molecular imaging of breast cancer | Breast | 2009 | 88 |
| 24 | Forkhead Transcription Factor FoxM1 Regulates Mitotic Entry and Prevents Spindle Defects in Cerebellar Granule Neuron Precursors | Molecular and Cellular Biology | 2007 | 84 |
| 25 | Trends in Epidemiology, Treatment, and Survival of Hepatocellular Carcinoma Patients Between 1998 and 2009 | Journal of Clinical Gastroenterology | 2014 | 80 |
| 26 | Understanding provision of chemotherapy to patients with end stage cancer: qualitative interview study | BMJ Supportive and Palliative Care | 2011 | 73 |
| 27 | Prognostic Significance of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand and Its Receptors in Adjuvantly Treated Stage III Colon Cancer Patients | Journal of Clinical Oncology | 2006 | 72 |
| 28 | Communication in palliative care: a review of recent literature | Current Opinion in Oncology | 2005 | 71 |
| 29 | Barriers to participating in genetic counseling and BRCA testing during primary treatment for breast cancer | Genetics in Medicine | 2007 | 67 |
| 30 | Daratumumab for Delayed Red-Cell Engraftment after Allogeneic Transplantation | New England Journal of Medicine | 2018 | 66 |
| 31 | Skeletal muscle mass loss and dose‐limiting toxicities in metastatic colorectal cancer patients | Journal of Cachexia, Sarcopenia and Muscle | 2019 | 65 |
| 32 | Hot flushes in breast cancer patients | Critical Reviews in Oncology/Hematology | 2006 | 64 |
| 33 | A CYP3A4 Phenotype–Based Dosing Algorithm for Individualized Treatment of Irinotecan | Clinical Cancer Research | 2010 | 63 |
| 34 | Renal angiomyolipoma in patients with tuberous sclerosis complex: findings from the TuberOus SClerosis registry to increase disease Awareness | Nephrology Dialysis Transplantation | 2019 | 55 |
| 35 | Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry | Journal of Pharmaceutical and Biomedical Analysis | 2010 | 54 |
| 36 | Universal Quantitative Kinase Assay Based on Diagonal SCX Chromatography and Stable Isotope Dimethyl Labeling Provides High-definition Kinase Consensus Motifs for PKA and Human Mps1 | Journal of Proteome Research | 2013 | 45 |
| 37 | Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme: a feasibility and safety study | Therapeutic Advances in Medical Oncology | 2019 | 45 |
| 38 | Development of a Chemical Genetic Approach for Human Aurora B Kinase Identifies Novel Substrates of the Chromosomal Passenger Complex | Molecular and Cellular Proteomics | 2012 | 44 |
| 39 | Method optimisation for peptide profiling of microdissected breast carcinoma tissue by matrix‐assisted laser desorption/ionisation‐time of flight and matrix‐assisted laser desorption/ionisation‐time of flight/time of flight‐mass spectrometry | Proteomics | 2005 | 43 |
| 40 | IL-4 Downregulates IL-1β and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine | Journal of Immunology | 2015 | 43 |
| 41 | Pharmaceutical and clinical development of phosphonate-based radiopharmaceuticals for the targeted treatment of bone metastases | Bone | 2016 | 43 |
| 42 | Urinary 5-HIAA measurement using automated on-line solid-phase extraction–high-performance liquid chromatography–tandem mass spectrometry | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2008 | 40 |
| 43 | A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and varying degrees of renal function | Cancer Chemotherapy and Pharmacology | 2015 | 40 |
| 44 | PD-L1 Antibody Comparison in Urothelial Carcinoma | European Urology | 2019 | 40 |
| 45 | Quantification of tamoxifen and three of its phase-I metabolites in human plasma by liquid chromatography/triple-quadrupole mass spectrometry | Journal of Pharmaceutical and Biomedical Analysis | 2011 | 39 |
| 46 | Circulating Tumor Cells as a Prognostic Factor in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: The CIRCUTEC Prospective Study | Clinical Chemistry | 2019 | 38 |
| 47 | Stage migration in breast cancer: surgical decisions concerning isolated tumour cells and micro-metastases in the sentinel lymph node | European Journal of Surgical Oncology | 2003 | 36 |
| 48 | A randomized phase II study investigating the addition of the specific COX-2 inhibitor celecoxib to docetaxel plus carboplatin as first-line chemotherapy for stage IC to IV epithelial ovarian cancer, Fallopian tube or primary peritoneal carcinomas: the DoCaCel study | Annals of Oncology | 2012 | 36 |
| 49 | Effects of CYP Induction by Rifampicin on Tamoxifen Exposure | Clinical Pharmacology and Therapeutics | 2012 | 34 |
| 50 | The role of response evaluation criteria in solid tumour in anticancer treatment evaluation: Results of a survey in the oncology community | European Journal of Cancer | 2014 | 34 |
