| # | Title | Journal | Year | Citations |
|---|
| 1 | Genomic correlates of response to CTLA-4 blockade in metastatic melanoma | Science | 2015 | 2,275 |
| 2 | Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy | Nature | 2016 | 1,243 |
| 3 | Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Assessment of Medication Risks with Emphasis on Recently Marketed Drugs. The EuroSCAR-Study | Journal of Investigative Dermatology | 2008 | 807 |
| 4 | European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa | Journal of the European Academy of Dermatology and Venereology | 2015 | 802 |
| 5 | Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study | British Journal of Dermatology | 2013 | 652 |
| 6 | Epidemiology of Melanoma and Nonmelanoma Skin Cancer—The Role of Sunlight | Advances in Experimental Medicine and Biology | 2008 | 582 |
| 7 | Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma | Nature Medicine | 2019 | 541 |
| 8 | ALDEN, an Algorithm for Assessment of Drug Causality in Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Comparison With Case–Control Analysis | Clinical Pharmacology and Therapeutics | 2010 | 529 |
| 9 | An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma | Nature | 2020 | 526 |
| 10 | Guidelines for the use of flow cytometry and cell sorting in immunological studies* | European Journal of Immunology | 2017 | 505 |
| 11 | Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 498 |
| 12 | Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis | Frontiers in Physiology | 2014 | 463 |
| 13 | Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab | Clinical Cancer Research | 2016 | 459 |
| 14 | Elevated levels of tumour necrosis factor (TNF)-α, interleukin (IL)-1β and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-α and IL-1β | British Journal of Dermatology | 2011 | 394 |
| 15 | Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel | Journal of the American Academy of Dermatology | 2008 | 393 |
| 16 | Fatal laryngeal attacks and mortality in hereditary angioedema due to C1-INH deficiency | Journal of Allergy and Clinical Immunology | 2012 | 354 |
| 17 | Diagnosis, monitoring and management of immune-related adverse drug reactions of anti-PD-1 antibody therapy | Cancer Treatment Reviews | 2016 | 354 |
| 18 | Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases | Allergo Journal International | 2014 | 338 |
| 19 | DNA Vaccines—How Far From Clinical Use? | International Journal of Molecular Sciences | 2018 | 329 |
| 20 | Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells | Journal of Experimental Medicine | 2011 | 324 |
| 21 | Angiogenesis drives psoriasis pathogenesis | International Journal of Experimental Pathology | 2009 | 291 |
| 22 | Anti-carcinogenic Effects of the Flavonoid Luteolin | Molecules | 2008 | 284 |
| 23 | Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms | European Journal of Cancer | 2015 | 269 |
| 24 | Interleukin-1 Beta—A Friend or Foe in Malignancies? | International Journal of Molecular Sciences | 2018 | 268 |
| 25 | Combined immune checkpoint blockade (anti-PD-1/anti-CTLA-4): Evaluation and management of adverse drug reactions | Cancer Treatment Reviews | 2017 | 257 |
| 26 | Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage | Nature Medicine | 2014 | 241 |
| 27 | Resistance Toward Chlorhexidine in Oral Bacteria – Is There Cause for Concern? | Frontiers in Microbiology | 2019 | 239 |
| 28 | [33] Photocarcinogenesis: UVA vs UVB | Methods in Enzymology | 2000 | 234 |
| 29 | Medications as Risk Factors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Children: A Pooled Analysis | Pediatrics | 2009 | 226 |
| 30 | Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells | Nature Medicine | 2018 | 216 |
| 31 | Depression in patients with hidradenitis suppurativa | Journal of the European Academy of Dermatology and Venereology | 2013 | 210 |
| 32 | Guideline for acute therapy and management of anaphylaxis | Allergo Journal International | 2014 | 210 |
| 33 | Air Pollution and Climate Change Effects on Allergies in the Anthropocene: Abundance, Interaction, and Modification of Allergens and Adjuvants | Environmental Science & Technology | 2017 | 193 |
| 34 | Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells | Immunity | 2012 | 184 |
| 35 | Epidemiology of Skin Cancer: Update 2019 | Advances in Experimental Medicine and Biology | 2020 | 184 |
| 36 | Costimulatory Molecules on Immunogenic Versus Tolerogenic Human Dendritic Cells | Frontiers in Immunology | 2013 | 180 |
| 37 | 13-cis Retinoic Acid Exerts its Specific Activity on Human Sebocytes through Selective Intracellular Isomerization to All-trans Retinoic Acid and Binding to Retinoid Acid Receptors | Journal of Investigative Dermatology | 2000 | 173 |
| 38 | Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid | Clinical Immunology | 2008 | 173 |
| 39 | Collagen VII plays a dual role in wound healing | Journal of Clinical Investigation | 2013 | 172 |
| 40 | Comparative in vitro study on cytotoxicity, antimicrobial activity, and binding capacity for pathophysiological factors in chronic wounds of alginate and silver‐containing alginate | Wound Repair and Regeneration | 2009 | 170 |
| 41 | Hidradenitis suppurativa: viewpoint on clinical phenotyping, pathogenesis and novel treatments | Experimental Dermatology | 2012 | 167 |
| 42 | ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression | Nature Medicine | 2012 | 164 |
| 43 | Tolerance through Education: How Tolerogenic Dendritic Cells Shape Immunity | Frontiers in Immunology | 2017 | 164 |
| 44 | Langerin neg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 158 |
| 45 | Differentiation-related changes of cytokeratin expression in cultured keratinocytes and in fetal, newborn, and adult epidermis | Experimental Cell Research | 1987 | 156 |
| 46 | Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens | Nature Genetics | 1994 | 153 |
| 47 | The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update | Allergy: European Journal of Allergy and Clinical Immunology | 2022 | 153 |
| 48 | Genetic deficiency of tartrate-resistant acid phosphatase associated with skeletal dysplasia, cerebral calcifications and autoimmunity | Nature Genetics | 2011 | 151 |
| 49 | Risk factors, clinical course and long‐term prognosis in hidradenitis suppurativa: a cross‐sectional study | British Journal of Dermatology | 2014 | 151 |
| 50 | The challenges of oral drug delivery via nanocarriers | Drug Delivery | 2018 | 151 |
