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exaly
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Department of Biochemistry and Molecular Genetics
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top-articles
Department of Biochemistry and Molecular Genetics
152
(top 1%)
papers
7.7K
(top 1%)
citations
44
(top 1%)
h
-index
85
(top 1%)
g
-index
203
all documents
9.6K
doc citations
1.6K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
American Journal of Respiratory and Critical Care Medicine
2019
866
2
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
Journal of Experimental Medicine
2017
755
3
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia
Nature
2021
524
4
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
Nature
2015
386
5
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
Nature Medicine
2015
359
6
Born to run: control of transcription elongation by RNA polymerase II
Nature Reviews Molecular Cell Biology
2018
304
7
Lung transplantation for patients with severe COVID-19
Science Translational Medicine
2020
246
8
Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation
Nature Genetics
2020
209
9
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Nature Metabolism
2020
206
10
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
Cell
2015
196
11
Chromatin signatures of cancer
Genes and Development
2015
171
12
Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides
Cancers
2019
167
13
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
Cell Reports
2017
164
14
Enhancer Logic and Mechanics in Development and Disease
Trends in Cell Biology
2018
146
15
Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Trends in Food Science and Technology
2020
146
16
Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies
Frontiers in Immunology
2020
131
17
MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes
Molecular Cell
2018
123
18
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia
Nature Genetics
2020
118
19
Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus
Antiviral Research
2017
113
20
Promoter bivalency favors an open chromatin architecture in embryonic stem cells
Nature Genetics
2018
113
21
Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries
Nature Communications
2018
112
22
Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory
ELife
2016
107
23
Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC–MS/MS
Nature Protocols
2019
106
24
A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer
Oncogene
2018
102
25
PAF1 regulation of promoter-proximal pause release via enhancer activation
Science
2017
95
26
An integrative ENCODE resource for cancer genomics
Nature Communications
2020
95
27
Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells
Oncotarget
2017
92
28
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging
Journal of Clinical Investigation
2021
86
29
Direct stimulation of NADP
+
synthesis through Akt-mediated phosphorylation of NAD kinase
Science
2019
85
30
Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex
Cell
2018
84
31
Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification
Molecular Cell
2017
81
32
Emerging concepts of epigenetic dysregulation in hematological malignancies
Nature Immunology
2016
77
33
Signal Percolation within a Bacterial Community
Cell Systems
2018
77
34
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
Genome Biology
2020
70
35
HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking
BMC Genomics
2017
69
36
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
ELife
2021
69
37
A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
Cancer Cell
2018
68
38
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia
Clinical Cancer Research
2019
66
39
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells
Science
2022
64
40
Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism
ELife
2017
62
41
Subtype-specific 3D genome alteration in acute myeloid leukaemia
Nature
2022
59
42
mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function
Proceedings of the National Academy of Sciences of the United States of America
2018
57
43
Genome-wide mapping of human DNA replication by optical replication mapping supports a stochastic model of eukaryotic replication
Molecular Cell
2021
57
44
Regulation of the imprinted
Dlk1-Dio3
locus by allele-specific enhancer activity
Genes and Development
2016
55
45
An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells
Science Advances
2018
55
46
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis
Science Translational Medicine
2018
55
47
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation
Genes and Development
2017
54
48
A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation
Nature Cell Biology
2021
54
49
The phytochemical, biological, and medicinal attributes of phytoecdysteroids: An updated review
Acta Pharmaceutica Sinica B
2021
51
50
SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression
Genes and Development
2017
48
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