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Top Articles

#TitleJournalYearCitations
1Xiaozhang Tie Improves Intestinal Motility in Rats With Cirrhotic Ascites by Regulating the Stem Cell Factor/c-kit Pathway in Interstitial Cells of CajalFrontiers in Pharmacology2020299
2Preparation and evaluation of self-microemulsifying drug delivery system of oridoninInternational Journal of Pharmaceutics2008252
3Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive systemActa Pharmacologica Sinica2017236
4Akt: A Double-Edged Sword in Cell Proliferation and Genome StabilityJournal of Oncology2012224
5A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fissionAutophagy2015201
6Advanced review of graphene-based nanomaterials in drug delivery systems: Synthesis, modification, toxicity and applicationMaterials Science and Engineering C2017186
7Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathwayAutophagy2014160
8Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk–Shell Structure Augment Cancer ChemotherapyNano Letters2020144
9Holistic quality evaluation of commercial white and red ginseng using a UPLC-QTOF-MS/MS-based metabolomics approachJournal of Pharmaceutical and Biomedical Analysis2012142
10Tanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancerCancer Letters2017137
11Status and future scope of hydrogels in wound healing: Synthesis, materials and evaluationEuropean Polymer Journal2020133
12The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivationAutophagy2014120
13Nanocarriers for the delivery of active ingredients and fractions extracted from natural products used in traditional Chinese medicine (TCM)Advances in Colloid and Interface Science2015107
14Tumor-specific carrier-free nanodrugs with GSH depletion and enhanced ROS generation for endogenous synergistic anti-tumor by a chemotherapy-photodynamic therapyChemical Engineering Journal2021106
15Ligand Controlled Regiodivergent C1 Insertion on Arynes for Construction of Phenanthridinone and Acridone AlkaloidsAngewandte Chemie - International Edition2015105
16Intron targeting-mediated and endogenous gene integrity-maintaining knockin in zebrafish using the CRISPR/Cas9 systemCell Research2015105
17Preventive and ameliorating effects of citrus d-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesityEuropean Journal of Pharmacology2013101
18Amplification of USP13 drives ovarian cancer metabolismNature Communications201699
19Comparative studies of polydatin and resveratrol on mutual transformation and antioxidative effect in vivoPhytomedicine201598
20Berberine inhibits PTP1B activity and mimics insulin actionBiochemical and Biophysical Research Communications201097
21Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barksPhytomedicine201187
22Extract of okra lowers blood glucose and serum lipids in high-fat diet-induced obese C57BL/6 miceJournal of Nutritional Biochemistry201486
23SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral productionScience Bulletin202184
24Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentationJournal of Clinical Investigation202183
25Optimization and in situ intestinal absorption of self-microemulsifying drug delivery system of oridoninInternational Journal of Pharmaceutics200981
26Nanostructured lipid carriers versus microemulsions for delivery of the poorly water-soluble drug luteolinInternational Journal of Pharmaceutics201479
27Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oilInternational Journal of Nanomedicine201278
28Application of proteomics to determine the mechanism of action of traditional Chinese medicine remediesJournal of Ethnopharmacology201477
29Neuroprotective Effects of Ginseng Phytochemicals: Recent PerspectivesMolecules201977
30Synergistic Mechanisms of Constituents in Herbal Extracts during Intestinal Absorption: Focus on Natural Occurring NanoparticlesPharmaceutics202077
31Metabolomics window into diabetic complicationsJournal of Diabetes Investigation201875
32Neuroprotective Effects of Ginsenosides against Cerebral IschemiaMolecules201974
33The complete chloroplast genome of Gentiana straminea (Gentianaceae), an endemic species to the Sino-Himalayan subregionGene201673
34Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessileOrganic Letters201571
35Advances in extraction and analysis of phenolic compounds from plant materialsChinese Journal of Natural Medicines201770
36Targeting adipocyte apoptosis: A novel strategy for obesity therapyBiochemical and Biophysical Research Communications201269
37Luteolin Alleviates Alcoholic Liver Disease Induced by Chronic and Binge Ethanol Feeding in MiceJournal of Nutrition201467
38USP21 prevents the generation of T-helper-1-like Treg cellsNature Communications201667
39Screening of anti-cancer agent using zebrafish: Comparison with the MTT assayBiochemical and Biophysical Research Communications201266
40MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosisOncotarget064
41JMJD6 is a tumorigenic factor and therapeutic target in neuroblastomaNature Communications201963
42Crosslinked Aspartic Acids as Helix‐Nucleating TemplatesAngewandte Chemie - International Edition201662
43Gastroprotective effect of a traditional Chinese herbal drug “Baishouwu” on experimental gastric lesions in ratsJournal of Ethnopharmacology200661
44Diverse Mechanisms of Antidiabetic Effects of the Different Procyanidin Oligomer Types of Two Different Cinnamon Species on db/db MiceJournal of Agricultural and Food Chemistry201261
45Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in miceScientific Reports201461
46Harmine is an inflammatory inhibitor through the suppression of NF-κB signalingBiochemical and Biophysical Research Communications201761
47Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery systemInternational Journal of Nanomedicine201260
48Collective Synthesis of Phenanthridinone through C–H Activation Involving a Pd-Catalyzed Aryne Multicomponent ReactionOrganic Letters201660
49Redox-responsive polymeric micelles formed by conjugating gambogic acid with bioreducible poly(amido amine)s for the co-delivery of docetaxel and MMP-9 shRNAActa Biomaterialia201860
50Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiencyScientific Reports201659