Department of Biochemistry

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#	Title	Journal	Year	Citations
1	Universal chemical assay for the detection and determination of siderophores	Analytical Biochemistry	1987	5,170
2	Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements	Cell	1987	2,161
3	Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain	Cell	1987	1,960
4	Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif	Cell	1988	1,753
5	The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter	Cell	1983	1,558
6	Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium	Cell	1985	1,069
7	Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen	Cell	1987	1,055
8	Expression of engrailed proteins in arthropods, annelids, and chordates	Cell	1989	1,048
9	Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction	Neuron	1989	991
10	O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation	Cell	1988	899
11	Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro	Cell	1985	894
12	The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain	Cell	1989	863
13	Order of events in the yeast secretory pathway	Cell	1981	816
14	Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II	Cell	1983	809
15	Transcriptional selectivity of viral genes in mammalian cells	Cell	1986	806
16	Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay	Analytical Biochemistry	1983	782
17	Fos-associated protein p39 is the product of the jun proto-oncogene	Science	1988	688
18	Isolation of a putative phospholipase c gene of drosophila, norpA, and its role in phototransduction	Cell	1988	660
19	Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing	Cell	1986	648
20	Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole	Cell	1982	603
21	Repetitive extragenic palindromic sequences: A major component of the bacterial genome	Cell	1984	554
22	Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts	Cell	1988	477
23	Glycosylation and processing of prepro-α-factor through the yeast secretory pathway	Cell	1984	445
24	Enterobactin, an iron transport compound from Salmonella typhimurium	Biochemical and Biophysical Research Communications	1970	437
25	Isolation of the yeast calmodulin gene: Calmodulin is an essential protein	Cell	1986	428
26	Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography	Analytical Biochemistry	1987	407
27	Identification and immunochemical analysis of biologically active Drosophila P element transposase	Cell	1986	368
28	SV40 gene expression is modulated by the cooperative binding of T antigen to DNA	Cell	1981	355
29	The carboxy-terminal segment of the yeast α-factor receptor is a regulatory domain	Cell	1988	329
30	Sp1 binds to promoter sequences and activates herpes simplex virus ‘immediate-early’ gene transcription in vitro	Nature	1985	327
31	Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast	Cell	1981	322
32	A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae	Cell	1989	316
33	The Drosophila ninaC locus encodes two photoreceptor cell specific proteins with domains homologous to protein kinases and the myosin heavy chain head	Cell	1988	312
34	Global flexibility in a sensory receptor: a site-directed cross-linking approach	Science	1987	279
35	Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila	Cell	1987	276
36	Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma	Analytical Biochemistry	1988	267
37	Characterization of drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene	Cell	1985	259
38	Expression of engrailed during segmentation in grasshopper and crayfish	Development (Cambridge)	1989	249
39	The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells	Nature	1989	238
40	Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila	Cell	1984	232
41	Pausing and attenuation of in vitro transcription in the rrnB operon of E. coli	Cell	1981	228
42	Biochemical analysis of transcriptional activation by Jun: Differential activity of c- and v-Jun	Cell	1989	224
43	v-jun encodes a nuclear protein with enhancer binding properties of AP-1	Cell	1988	213
44	rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye	Cell	1988	200
45	T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication	Molecular and Cellular Biology	1986	173
46	Essential contact residues within SV40 large T antigen binding sites I and II identified by alkylation-interference	Cell	1984	164
47	SV40 T antigen binding site mutations that affect autoregulation	Cell	1983	157
48	Ca2+ release from mitochondria induced by prooxidants	Free Radical Biology and Medicine	1988	157
49	A purified Drosophila homeodomain protein represses transcription in vitro	Cell	1989	157
50	Sensitivity amplification in biochemical systems	Quarterly Reviews of Biophysics	1982	156

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