| # | Title | Journal | Year | Citations |
|---|
| 1 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 2 | Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain | Journal of Pain | 2009 | 1,960 |
| 3 | Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking CessationA Randomized Controlled Trial | JAMA - Journal of the American Medical Association | 2006 | 1,231 |
| 4 | Physician-patient communication. The relationship with malpractice claims among primary care physicians and surgeons | JAMA - Journal of the American Medical Association | 1997 | 1,153 |
| 5 | cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway | Cell | 1997 | 1,007 |
| 6 | Adult Consequences of Fetal Growth Restriction | Clinical Obstetrics and Gynecology | 2006 | 776 |
| 7 | Subcutaneous Golimumab Induces Clinical Response and Remission in Patients With Moderate-to-Severe Ulcerative Colitis | Gastroenterology | 2014 | 753 |
| 8 | Cotransplantation of HLA-Identical Sibling Culture-Expanded Mesenchymal Stem Cells and Hematopoietic Stem Cells in Hematologic Malignancy Patients | Biology of Blood and Marrow Transplantation | 2005 | 745 |
| 9 | Educational Strategies to Promote Clinical Diagnostic Reasoning | New England Journal of Medicine | 2006 | 698 |
| 10 | The Essentiality of N-3 Fatty Acids for the Development and Function of the Retina and Brain | Annual Review of Nutrition | 1988 | 641 |
| 11 | The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer | Trends in Molecular Medicine | 2008 | 632 |
| 12 | Subcutaneous Golimumab Maintains Clinical Response in Patients With Moderate-to-Severe Ulcerative Colitis | Gastroenterology | 2014 | 605 |
| 13 | Overtreating Chronic Back Pain: Time to Back Off? | Journal of the American Board of Family Medicine | 2009 | 595 |
| 14 | NF-κB and cancer—identifying targets and mechanisms | Current Opinion in Genetics and Development | 2008 | 568 |
| 15 | Hip Fracture in Women without Osteoporosis | Journal of Clinical Endocrinology and Metabolism | 2005 | 542 |
| 16 | Bronchiectasis | New England Journal of Medicine | 2002 | 535 |
| 17 | Inhibition of KIT Tyrosine Kinase Activity: A Novel Molecular Approach to the Treatment of KIT-Positive Malignancies | Journal of Clinical Oncology | 2002 | 526 |
| 18 | Interventional Therapies, Surgery, and Interdisciplinary Rehabilitation for Low Back Pain | Spine | 2009 | 484 |
| 19 | How Accurate Is Clinician Reporting of Chemotherapy Adverse Effects? A Comparison With Patient-Reported Symptoms From the Quality-of-Life Questionnaire C30 | Journal of Clinical Oncology | 2004 | 475 |
| 20 | Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study | JAMA Surgery | 2018 | 474 |
| 21 | Dasatinib (BMS-354825), a Dual SRC/ABL Kinase Inhibitor, Inhibits the Kinase Activity of Wild-Type, Juxtamembrane, and Activation Loop Mutant KIT Isoforms Associated with Human Malignancies | Cancer Research | 2006 | 437 |
| 22 | The comparative reductions of the plasma lipids and lipoproteins by dietary polyunsaturated fats: Salmon oil versus vegetable oils | Metabolism: Clinical and Experimental | 1983 | 431 |
| 23 | Mifepristone, a Glucocorticoid Receptor Antagonist, Produces Clinical and Metabolic Benefits in Patients with Cushing's Syndrome | Journal of Clinical Endocrinology and Metabolism | 2012 | 409 |
| 24 | Inhibition of KIT Tyrosine Kinase Activity: A Novel Molecular Approach to the Treatment of KIT-Positive Malignancies | Journal of Clinical Oncology | 2002 | 399 |
| 25 | WNK kinases regulate thiazide-sensitive Na-Cl cotransport | Journal of Clinical Investigation | 2003 | 394 |
| 26 | Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study | BMJ, The | 2022 | 393 |
| 27 | Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study | American Journal of Medicine | 2003 | 366 |
| 28 | Clinical and genetic issues in familial dilated cardiomyopathy | Journal of the American College of Cardiology | 2005 | 357 |
| 29 | Managed care, time pressure, and physician job satisfaction: Results from the physician worklife study | Journal of General Internal Medicine | 2000 | 348 |
| 30 | Opioids for Chronic Noncancer Pain: Prediction and Identification of Aberrant Drug-Related Behaviors: A Review of the Evidence for an American Pain Society and American Academy of Pain Medicine Clinical Practice Guideline | Journal of Pain | 2009 | 333 |
| 31 | Differences in coronary mortality can be explained by differences in cholesterol and saturated fat intakes in 40 countries but not in France and Finland. A paradox. | Circulation | 1993 | 331 |
| 32 | Nonsurgical Interventional Therapies for Low Back Pain | Spine | 2009 | 327 |
| 33 | Perioperative Glucocorticoid Coverage A Reassessment 42 Years After Emergence of a Problem | Annals of Surgery | 1994 | 326 |
| 34 | Dendrodendritic Inhibition in the Olfactory Bulb Is Driven by NMDA Receptors | Journal of Neuroscience | 1998 | 321 |
| 35 | Cost-effectiveness model for colon cancer screening | Gastroenterology | 1995 | 308 |
| 36 | Research Gaps on Use of Opioids for Chronic Noncancer Pain: Findings From a Review of the Evidence for an American Pain Society and American Academy of Pain Medicine Clinical Practice Guideline | Journal of Pain | 2009 | 307 |
| 37 | Celecoxib Versus Naproxen and Diclofenac in Osteoarthritis Patients: SUCCESS-I Study | American Journal of Medicine | 2006 | 302 |
| 38 | Dietary effects on brain fatty acid composition: the reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain, erythrocytes, and plasma of rhesus monkeys. | Journal of Lipid Research | 1990 | 297 |
| 39 | Clinical characteristics of fibrositis | Arthritis and Rheumatism | 1983 | 295 |
| 40 | Characteristics of Patients with Asthma Within a Large HMO | American Journal of Respiratory and Critical Care Medicine | 1998 | 285 |
| 41 | Type VI Collagen Anchors Endothelial Basement Membranes by Interacting with Type IV Collagen | Journal of Biological Chemistry | 1997 | 282 |
| 42 | Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review | Journal of Pain and Symptom Management | 2004 | 274 |
| 43 | A Calcineurin-NFATc3-Dependent Pathway Regulates Skeletal Muscle Differentiation and Slow Myosin Heavy-Chain Expression | Molecular and Cellular Biology | 2000 | 271 |
| 44 | Reduction of postprandial triglyceridemia in humans by dietary n-3 fatty acids | Journal of Lipid Research | 1988 | 269 |
| 45 | Evaluation of asymptomatic microscopic hematuria in adults: the American Urological Association best practice policy—part II: patient evaluation, cytology, voided markers, imaging, cystoscopy, nephrology evaluation, and follow-up | Urology | 2001 | 263 |
| 46 | Validation of 2 Depression Screening Tools in Dialysis Patients | American Journal of Kidney Diseases | 2005 | 260 |
| 47 | Legalizing Assisted Suicide — Views of Physicians in Oregon | New England Journal of Medicine | 1996 | 256 |
| 48 | Regulation of Bone Mass in Mice by the Lipoxygenase Gene Alox15 | Science | 2004 | 255 |
| 49 | Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells | Blood | 2004 | 252 |
| 50 | Dietary effects on brain fatty acid composition: the reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain, erythrocytes, and plasma of rhesus monkeys | Journal of Lipid Research | 1990 | 251 |
