| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | The 90-kDa Molecular Chaperone Family | | 1998 | 933 |
| 4 | Structure and dynamics of molecular networks: A novel paradigm of drug discovery | | 2013 | 779 |
| 5 | The efficiency of multi-target drugs: the network approach might help drug design | Trends in Pharmacological Sciences | 2005 | 745 |
| 6 | Induced fit, conformational selection and independent dynamic segments: an extended view of binding events | Trends in Biochemical Sciences | 2010 | 708 |
| 7 | Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila | Nature | 2011 | 574 |
| 8 | The role of structural disorder in the function of RNA and protein chaperones | FASEB Journal | 2004 | 496 |
| 9 | Effects of ultraviolet radiation on plant cells | Micron | 2002 | 445 |
| 10 | Structural disorder throws new light on moonlighting | Trends in Biochemical Sciences | 2005 | 430 |
| 11 | Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy | | 2004 | 387 |
| 12 | Vitamin C: update on physiology and pharmacology | British Journal of Pharmacology | 2009 | 356 |
| 13 | Heat shock proteins as emerging therapeutic targets | British Journal of Pharmacology | 2005 | 337 |
| 14 | Structure and dynamics of core/periphery networks | Journal of Complex Networks | 2013 | 296 |
| 15 | Chance and necessity in the evolution of minimal metabolic networks | Nature | 2006 | 219 |
| 16 | Network analysis of protein dynamics | FEBS Letters | 2007 | 193 |
| 17 | On the role of 4-hydroxynonenal in health and disease | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2015 | 189 |
| 18 | A Nucleotide-dependent Molecular Switch Controls ATP Binding at the C-terminal Domain of Hsp90 | Journal of Biological Chemistry | 2002 | 186 |
| 19 | Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1 | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2002 | 182 |
| 20 | Gain-of-Function Mutations Associated with Hereditary Pancreatitis Enhance Autoactivation of Human Cationic Trypsinogen | Biochemical and Biophysical Research Communications | 2000 | 176 |
| 21 | SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks | BMC Systems Biology | 2013 | 169 |
| 22 | Community Landscapes: An Integrative Approach to Determine Overlapping Network Module Hierarchy, Identify Key Nodes and Predict Network Dynamics | PLoS ONE | 2010 | 168 |
| 23 | Antioxidant measurements | Physiological Measurement | 2007 | 159 |
| 24 | Aging and molecular chaperones | Experimental Gerontology | 2003 | 152 |
| 25 | Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners | Journal of Cell Science | 2005 | 133 |
| 26 | A Role for SKN-1/Nrf in Pathogen Resistance and Immunosenescence in Caenorhabditis elegans | PLoS Pathogens | 2012 | 132 |
| 27 | Selection and Characterization of a Novel DNA Aptamer for Label-Free Fluorescence Biosensing of Ochratoxin A | Toxins | 2014 | 124 |
| 28 | Roles of heat shock factor 1 beyond the heat shock response | Cellular and Molecular Life Sciences | 2018 | 124 |
| 29 | DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic–pituitary–adrenal axis activity and to early life emotional abuse | Psychiatry Research | 2018 | 120 |
| 30 | Molecular chaperones and the aging process | Biogerontology | 2000 | 116 |
| 31 | ComPPI: a cellular compartment-specific database for protein–protein interaction network analysis | Nucleic Acids Research | 2015 | 116 |
| 32 | Mammalian Hsp70 and Hsp110 Proteins Bind to RNA Motifs Involved in mRNA Stability | Journal of Biological Chemistry | 1999 | 115 |
| 33 | Strong links are important, but weak links stabilize them | Trends in Biochemical Sciences | 2004 | 115 |
| 34 | The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: From antioxidant to epigenetic therapy | Ageing Research Reviews | 2021 | 115 |
| 35 | Molecular chaperones, stress proteins and redox homeostasis | BioFactors | 2003 | 113 |
| 36 | Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2008 | 113 |
| 37 | Creative elements: network-based predictions of active centres in proteins and cellular and social networks | Trends in Biochemical Sciences | 2008 | 113 |
| 38 | Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis | Human Mutation | 2006 | 110 |
| 39 | Oxytocin Receptor Gene Polymorphisms Are Associated with Human Directed Social Behavior in Dogs (Canis familiaris) | PLoS ONE | 2014 | 102 |
| 40 | Chaperones and aging: role in neurodegeneration and in other civilizational diseases | Neurochemistry International | 2002 | 100 |
| 41 | Forgetting Is Regulated via Musashi-Mediated Translational Control of the Arp2/3 Complex | Cell | 2014 | 100 |
| 42 | Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch | Aging Cell | 2003 | 98 |
| 43 | Association of polymorphisms in the dopamine D4 receptor gene and the activity‐impulsivity endophenotype in dogs | Animal Genetics | 2007 | 97 |
| 44 | Multiple weak hits confuse complex systems: A transcriptional regulatory network as an example | Physical Review E | 2005 | 96 |
| 45 | Endoplasmic reticulum: nutrient sensor in physiology and pathology | Trends in Endocrinology and Metabolism | 2009 | 95 |
| 46 | The NRF2‐related interactome and regulome contain multifunctional proteins and fine‐tuned autoregulatory loops | FEBS Letters | 2012 | 95 |
| 47 | Acetaminophen induces ER dependent signaling in mouse liver | Archives of Biochemistry and Biophysics | 2007 | 93 |
| 48 | ModuLand plug-in for Cytoscape: determination of hierarchical layers of overlapping network modules and community centrality | Bioinformatics | 2012 | 91 |
| 49 | Aptamer-based biochips for label-free detection of plant virus coat proteins by SPR imaging | Analyst, The | 2010 | 90 |
| 50 | Hsp90 Inhibition Accelerates Cell Lysis | Journal of Biological Chemistry | 2003 | 89 |
