678(top 1%)
papers
20.9K(top 1%)
citations
68(top 1%)
h-index
118(top 1%)
g-index
781
all documents
22.3K
doc citations
2.9K
citing journals

Top Articles

#TitleJournalYearCitations
1Genetics of rheumatoid arthritis contributes to biology and drug discoveryNature20141,974
2Activated human T cells directly induce osteoclastogenesis from human monocytes: Possible role of T cells in bone destruction in rheumatoid arthritis patientsArthritis and Rheumatism2001577
3Comparison of Disease Activity Score (DAS)28- erythrocyte sedimentation rate and DAS28- C-reactive protein threshold valuesAnnals of the Rheumatic Diseases2007340
4Japanese Population Structure, Based on SNP Genotypes from 7003 Individuals Compared to Other Ethnic Groups: Effects on Population-Based Association StudiesAmerican Journal of Human Genetics2008327
5Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosusProceedings of the National Academy of Sciences of the United States of America2010324
6Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese populationNature Genetics2012285
7Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositisRheumatology2010261
8Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositisRheumatology2012261
9Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analysesPharmacogenetics and Genomics2002248
10Japanese Guideline for the Management of Hyperuricemia and Gout: Second EditionNucleosides, Nucleotides and Nucleic Acids2011244
11A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibilityNature Genetics2010241
12Intraarticular inflammatory cytokines in acute anterior cruciate ligament injured kneeKnee2003238
13Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: possible association with malignancyAnnals of the Rheumatic Diseases2012220
14Variations in the FTO gene are associated with severe obesity in the JapaneseJournal of Human Genetics2008219
15Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA StudyArthritis Research and Therapy2010217
16Serum matrix metalloproteinase 3 as a predictor of the degree of joint destruction during the six months after measurement, in patients with early rheumatoid arthritisArthritis and Rheumatism2000212
17Validation of a Japanese version of the Stanford Health Assessment Questionnaire in 3,763 patients with rheumatoid arthritisArthritis and Rheumatism2003206
18Molecular aspects of rheumatoid arthritis: chemokines in the joints of patientsFEBS Journal2008202
19IL‐17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti‐TNF‐α antibody: A novel mechanism of osteoclastogenesis by IL‐17Journal of Cellular Biochemistry2009183
20IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in ratsArthritis Research and Therapy2007164
21Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose–response study of AMG 162 (Denosumab) in patients with RheumatoId arthritis on methotrexate to Validate inhibitory effect on bone Erosion (DRIVE)—a 12-month, multicentre, randomised, double-blind, placebo-controlled, phase II clinical trialAnnals of the Rheumatic Diseases2016157
22Cytokine profiles in polymyositis and dermatomyositis complicated by rapidly progressive or chronic interstitial lung diseaseRheumatology2014153
23Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid ArthritisPLoS Genetics2013146
24Increased ferritin predicts development and severity of acute interstitial lung disease as a complication of dermatomyositisRheumatology2010143
25Mortality and cause of death in Japanese patients with rheumatoid arthritis based on a large observational cohort, IORRAScandinavian Journal of Rheumatology2010138
26Association betweenPADI4 and rheumatoid arthritis: A replication studyArthritis and Rheumatism2005133
27Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritisNature Genetics2017130
28Increased CD40 Expression on Muscle Cells of Polymyositis and Dermatomyositis: Role of CD40-CD40 Ligand Interaction in IL-6, IL-8, IL-15, and Monocyte Chemoattractant Protein-1 ProductionJournal of Immunology2000127
29Estimates of the prevalence of and current treatment practices for rheumatoid arthritis in Japan using reimbursement data from health insurance societies and the IORRA cohort (I)Modern Rheumatology2014124
30A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritisRheumatology2008123
31Complications and features after joint surgery in rheumatoid arthritis patients treated with tumour necrosis factor-  blockers: perioperative interruption of tumour necrosis factor-  blockers decreases complications?Rheumatology2010123
32IFN-γ-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKLEuropean Journal of Immunology2005121
33Tofacitinib, an oral Janus kinase inhibitor, as monotherapy or with background methotrexate, in Japanese patients with rheumatoid arthritis: an open-label, long-term extension studyArthritis Research and Therapy2016117
34Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese populationJournal of Human Genetics2009115
35A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in JapanesePLoS Genetics2012115
36Association of functional polymorphisms of matrix metalloproteinase (MMP)-1 and MMP-3 genes with colorectal cancerInternational Journal of Cancer2002112
37A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5′ flanking region of SMYD3 is a risk factor for human cancersNature Genetics2005112
38Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled phase 3 trialAnnals of the Rheumatic Diseases2019105
39The molecular mechanism of osteoclastogenesis in rheumatoid arthritisArthritis Research2002104
40Japan College of Rheumatology guideline for the use of methotrexate in patients with rheumatoid arthritisModern Rheumatology2019104
41Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosusAnnals of the Rheumatic Diseases2021103
42Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese populationRheumatology2006102
43Association between PADI4 and rheumatoid arthritis: a meta-analysisRheumatology2006102
44Golimumab in combination with methotrexate in Japanese patients with active rheumatoid arthritis: results of the GO-FORTH studyAnnals of the Rheumatic Diseases2012102
45Initial predictors of poor survival in myositis-associated interstitial lung disease: a multicentre cohort of 497 patientsRheumatology2018101
46Safety and effectiveness of adalimumab in Japanese rheumatoid arthritis patients: Postmarketing surveillance report of 7740 patientsModern Rheumatology2014100
47ARTHROSCOPIC SYNOVECTOMY OF THE ELBOW IN RHEUMATOID ARTHRITISJournal of Bone and Joint Surgery - Series A200291
48Increased risk of tuberculosis in patients with rheumatoid arthritis in JapanAnnals of the Rheumatic Diseases200690
49Frequency of Class III and IV Nephritis in Systemic Lupus Erythematosus Without Clinical Renal Involvement: An Analysis of Predictive MeasuresJournal of Rheumatology201289
50Large-Scale Single-Nucleotide Polymorphism (SNP) and Haplotype Analyses, Using Dense SNP Maps, of 199 Drug-Related Genes in 752 Subjects: the Analysis of the Association between Uncommon SNPs within Haplotype Blocks and the Haplotypes Constructed with Haplotype-Tagging SNPsAmerican Journal of Human Genetics200488