# | Title | Journal | Year | Citations |
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1 | Gene Expression Levels and Immunolocalization of Organic Ion Transporters in the Human Kidney | Journal of the American Society of Nephrology: JASN | 2002 | 450 |
2 | Cellular and molecular aspects of drug transport in the kidney | Kidney International | 2000 | 404 |
3 | Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H+-organic cation antiporters | Biochemical Pharmacology | 2007 | 369 |
4 | Identification and Functional Characterization of a New Human Kidney–Specific H+/Organic Cation Antiporter, Kidney-Specific Multidrug and Toxin Extrusion 2 | Journal of the American Society of Nephrology: JASN | 2006 | 348 |
5 | cDNA Cloning and Functional Expression of a Novel Rat Kidney Organic Cation Transporter, OCT2 | Biochemical and Biophysical Research Communications | 1996 | 335 |
6 | Metformin is a Superior Substrate for Renal Organic Cation Transporter OCT2 rather than Hepatic OCT1 | Drug Metabolism and Pharmacokinetics | 2005 | 313 |
7 | Cisplatin and Oxaliplatin, but Not Carboplatin and Nedaplatin, Are Substrates for Human Organic Cation Transporters (SLC22A1–3 and Multidrug and Toxin Extrusion Family) | Journal of Pharmacology and Experimental Therapeutics | 2006 | 300 |
8 | Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1) | Journal of Pharmacology and Experimental Therapeutics | 1992 | 261 |
9 | Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer | Cancer Chemotherapy and Pharmacology | 2012 | 257 |
10 | Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity | Biochemical Pharmacology | 2007 | 217 |
11 | Immuno-Localization of H+/Peptide Cotransporter in Rat Digestive Tract | Biochemical and Biophysical Research Communications | 1996 | 213 |
12 | Effect of clarithromycin on renal excretion of digoxin: Interaction with P-glycoprotein* | Clinical Pharmacology and Therapeutics | 1998 | 201 |
13 | C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation | Pharmacogenetics and Genomics | 2002 | 186 |
14 | Cloning and characterization of a rat H+/peptide cotransporter mediating absorption of beta-lactam antibiotics in the intestine and kidney | Journal of Pharmacology and Experimental Therapeutics | 1995 | 185 |
15 | Cloning and Functional Characterization of a Novel Rat Organic Anion Transporter Mediating Basolateral Uptake of Methotrexate in the Kidney | Journal of Biological Chemistry | 1996 | 182 |
16 | CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation | Pharmacogenetics and Genomics | 2004 | 182 |
17 | Creatinine Transport by Basolateral Organic Cation Transporter hOCT2 in the Human Kidney | Pharmaceutical Research | 2004 | 180 |
18 | Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity | Biochemical Pharmacology | 2010 | 180 |
19 | Renal Transport of Adefovir, Cidofovir, and Tenofovir by SLC22A Family Members (hOAT1, hOAT3, and hOCT2) | Pharmaceutical Research | 2007 | 174 |
20 | An up-date review on individualized dosage adjustment of calcineurin inhibitors in organ transplant patients | | 2006 | 173 |
21 | Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy* | Clinical Pharmacology and Therapeutics | 1997 | 170 |
22 | Involvement of Human Multidrug and Toxin Extrusion 1 in the Drug Interaction between Cimetidine and Metformin in Renal Epithelial Cells | Journal of Pharmacology and Experimental Therapeutics | 2009 | 170 |
23 | (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) Peptide Transporters: Structure, Function, Regulation and Application for Drug Delivery | Current Drug Metabolism | 2004 | 167 |
24 | Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs | Journal of Pharmacology and Experimental Therapeutics | 1998 | 165 |
25 | Targeted Disruption of the Multidrug and Toxin Extrusion 1 (Mate1) Gene in Mice Reduces Renal Secretion of Metformin | Molecular Pharmacology | 2009 | 162 |
26 | Metformin Transport by Renal Basolateral Organic Cation Transporter hOCT2 | Pharmaceutical Research | 2005 | 156 |
27 | Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics | British Journal of Pharmacology | 2011 | 155 |
28 | Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles | Biochimica Et Biophysica Acta - Biomembranes | 1984 | 152 |
29 | Association between tubular toxicity of cisplatin and expression of organic cation transporter rOCT2 (Slc22a2) in the rat | Biochemical Pharmacology | 2005 | 152 |
30 | Gender differences in expression of organic cation transporter OCT2 in rat kidney | FEBS Letters | 1999 | 148 |
31 | Organic cation transporter OCT/SLC22A and H+/organic cation antiporter MATE/SLC47A are key molecules for nephrotoxicity of platinum agents | Biochemical Pharmacology | 2011 | 148 |
32 | Molecular cloning and tissue distribution of rat peptide transporter PEPT2 | Biochimica Et Biophysica Acta - Biomembranes | 1996 | 135 |
33 | Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy | Kidney International | 2002 | 132 |
34 | Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A) | Biochemical Pharmacology | 2008 | 131 |
35 | Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1 | American Journal of Physiology - Cell Physiology | 2008 | 126 |
36 | Hormonal regulation of organic cation transporter OCT2 expression in rat kidney | FEBS Letters | 2000 | 125 |
37 | Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients | Pharmacogenetics and Genomics | 2006 | 125 |
38 | Novel riboflavin transporter family RFVT/SLC52: Identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52 | Molecular Aspects of Medicine | 2013 | 125 |
39 | Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney | FEBS Letters | 1998 | 124 |
40 | SLCO4C1 Transporter Eliminates Uremic Toxins and Attenuates Hypertension and Renal Inflammation | Journal of the American Society of Nephrology: JASN | 2009 | 124 |
41 | A Novel Approach to Therapeutic Angiogenesis for Patients With Critical Limb Ischemia by Sustained Release of Basic Fibroblast Growth Factor Using Biodegradable Gelatin Hydrogel An Initial Report of the Phase I-IIa Study | Circulation Journal | 2007 | 121 |
42 | Identification and Comparative Functional Characterization of a New Human Riboflavin Transporter hRFT3 Expressed in the Brain | Journal of Nutrition | 2010 | 121 |
43 | Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation | Clinical Pharmacology and Therapeutics | 2001 | 120 |
44 | Molecular Cloning, Functional Characterization and Tissue Distribution of Rat H+/Organic Cation Antiporter MATE1 | Pharmaceutical Research | 2006 | 120 |
45 | cDNA Cloning, Functional Characterization, and Tissue Distribution of an Alternatively Spliced Variant of Organic Cation Transporter hOCT2 Predominantly Expressed in the Human Kidney | Journal of the American Society of Nephrology: JASN | 2002 | 114 |
46 | Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1 | Biochemical Pharmacology | 2005 | 114 |
47 | Effect of intestinal P-glycoprotein on daily tacrolimus trough level in a living-donor small bowel recipient | Clinical Pharmacology and Therapeutics | 2000 | 109 |
48 | Peptide transporter in the rat small intestine: ultrastructural localization and the effect of starvation and administration of amino acids | The Histochemical Journal | 1999 | 103 |
49 | Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney | Molecular Pharmacology | 1999 | 102 |
50 | INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity | Blood | 2007 | 100 |