| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy | Nature Reviews Molecular Cell Biology | 2014 | 2,444 |
| 3 | Small-sample estimation of negative binomial dispersion, with applications to SAGE data | Biostatistics | 2007 | 939 |
| 4 | Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells | Nature Immunology | 2017 | 504 |
| 5 | TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway | Science Signaling | 2016 | 453 |
| 6 | Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases | EMBO Journal | 2011 | 432 |
| 7 | XIAP discriminates between type I and type II FAS-induced apoptosis | Nature | 2009 | 421 |
| 8 | miR‐223: infection, inflammation and cancer | Journal of Internal Medicine | 2013 | 360 |
| 9 | Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 | EMBO Journal | 2020 | 330 |
| 10 | A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii | Immunity | 2012 | 311 |
| 11 | How the Bcl-2 family of proteins interact to regulate apoptosis | Cell Research | 2006 | 301 |
| 12 | The cellular and molecular basis for malaria parasite invasion of the human red blood cell | Journal of Cell Biology | 2012 | 285 |
| 13 | A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment | Cancer Research | 2018 | 269 |
| 14 | The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway | Nature Immunology | 2013 | 264 |
| 15 | Complementarity and redundancy of IL-22-producing innate lymphoid cells | Nature Immunology | 2016 | 211 |
| 16 | Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities | Cell Death and Differentiation | 2021 | 197 |
| 17 | Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum | Trends in Parasitology | 2012 | 148 |
| 18 | Sex-specific adipose tissue imprinting of regulatory T cells | Nature | 2020 | 141 |
| 19 | IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization | Nature Communications | 2019 | 139 |
| 20 | Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1 | Blood | 2016 | 127 |
| 21 | Id2 expression delineates differential checkpoints in the genetic program of CD8α+and CD103+dendritic cell lineages | EMBO Journal | 2011 | 121 |
| 22 | Familial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulator NPRL3 | Annals of Neurology | 2016 | 116 |
| 23 | Modeling Breast Cancer Using CRISPR-Cas9–Mediated Engineering of Human Breast Organoids | Journal of the National Cancer Institute | 2020 | 104 |
| 24 | Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes | Blood | 2014 | 103 |
| 25 | Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia | Blood | 2007 | 98 |
| 26 | The role of apoptosis in megakaryocytes and platelets | British Journal of Haematology | 2014 | 97 |
| 27 | Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells | Oncotarget | 2015 | 97 |
| 28 | A Toxoplasma gondii Gluconeogenic Enzyme Contributes to Robust Central Carbon Metabolism and Is Essential for Replication and Virulence | Cell Host and Microbe | 2015 | 95 |
| 29 | GFI1B mutation causes a bleeding disorder with abnormal platelet function | Journal of Thrombosis and Haemostasis | 2013 | 91 |
| 30 | Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll‐like receptor signaling | Immunology and Cell Biology | 2008 | 90 |
| 31 | Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis | Blood | 2015 | 84 |
| 32 | Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion | Cell Death and Differentiation | 2016 | 76 |
| 33 | IL-11 signaling as a therapeutic target for cancer | Immunotherapy | 2015 | 73 |
| 34 | The regulation of the development and function of dendritic cell subsets by GM-CSF: More than a hematopoietic growth factor | Molecular Immunology | 2012 | 70 |
| 35 | Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use | Blood | 2018 | 67 |
| 36 | Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury | American Journal of Respiratory Cell and Molecular Biology | 2018 | 66 |
| 37 | Therapeutic blockade of activin-A improves NK cell function and antitumor immunity | Science Signaling | 2019 | 64 |
| 38 | Consequences of the combined loss of BOK and BAK or BOK and BAX | Cell Death and Disease | 2013 | 62 |
| 39 | PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling | Genome Medicine | 2021 | 62 |
| 40 | AMA1 and MAEBL are important forPlasmodium falciparumsporozoite infection of the liver | Cellular Microbiology | 2017 | 60 |
| 41 | Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan | Blood | 2014 | 58 |
| 42 | EIF2S3Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO | Human Mutation | 2017 | 57 |
| 43 | Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression | Cancer Cell | 2017 | 57 |
| 44 | The inflammatory cytokine, GM‐CSF, alters the developmental outcome of murine dendritic cells | European Journal of Immunology | 2012 | 55 |
| 45 | A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo | Blood | 2014 | 52 |
| 46 | Food knowledge and psychological state predict adherence to a gluten‐free diet in a survey of 5310 Australians and New Zealanders with coeliac disease | Alimentary Pharmacology and Therapeutics | 2018 | 50 |
| 47 | NF‐κB1, NF‐κB2 and c‐Rel differentially regulate susceptibility to colitis‐associated adenoma development in C57BL/6 mice | Journal of Pathology | 2015 | 49 |
| 48 | MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development | Blood | 2015 | 47 |
| 49 | Cytoskeletal and membrane remodelling during malaria parasite invasion of the human erythrocyte | British Journal of Haematology | 2011 | 46 |
| 50 | The Colony-Stimulating Factors and Cancer | Cancer Immunology Research | 2013 | 45 |
