| # | Title | Journal | Year | Citations |
|---|
| 1 | Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 | Cell | 1995 | 2,144 |
| 2 | Impact of tricuspid regurgitation on long-term survival | Journal of the American College of Cardiology | 2004 | 1,328 |
| 3 | Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup | Nature Reviews Nephrology | 2017 | 946 |
| 4 | Cytokines and Cytokine Receptors in Advanced Heart Failure | Circulation | 2001 | 903 |
| 5 | K + Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension | Science | 2011 | 866 |
| 6 | Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing | Nature Medicine | 1999 | 814 |
| 7 | Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model | Science Translational Medicine | 2012 | 684 |
| 8 | Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart. | Journal of Clinical Investigation | 1993 | 642 |
| 9 | Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential | Journal of Cell Science | 2004 | 616 |
| 10 | β-cells in type II diabetes mellitus | Diabetes | 1991 | 607 |
| 11 | The Aneurysm Detection and Management Study Screening Program | Archives of Internal Medicine | 2000 | 596 |
| 12 | Frailty and Risk of Falls, Fracture, and Mortality in Older Women: The Study of Osteoporotic Fractures | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2007 | 569 |
| 13 | Activation of Protein Kinase C in Glomerular Cells in Diabetes: Mechanisms and Potential Links to the Pathogenesis of Diabetic Glomerulopathy | Diabetes | 1994 | 554 |
| 14 | Effectiveness of seven-valent pneumococcal conjugate vaccine against invasive pneumococcal disease: a matched case-control study | Lancet, The | 2006 | 543 |
| 15 | Rupture Rate of Large Abdominal Aortic Aneurysms in Patients Refusing or Unfit for Elective Repair | JAMA - Journal of the American Medical Association | 2002 | 501 |
| 16 | Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. | Journal of Clinical Investigation | 1995 | 482 |
| 17 | Central Nervous System–Active Medications and Risk for Falls in Older Women | Journal of the American Geriatrics Society | 2002 | 458 |
| 18 | A Mechanism of Central Sleep Apnea in Patients with Heart Failure | New England Journal of Medicine | 1999 | 453 |
| 19 | Role for Protein Kinase C in the Mediation of Increased Fibronectin Accumulation by Mesangial Cells Grown in High-Glucose Medium | Diabetes | 1993 | 443 |
| 20 | Eicosanoids and the gastrointestinal tract | Gastroenterology | 1995 | 384 |
| 21 | Natural history of hepatitis C | Hepatology | 1997 | 382 |
| 22 | A Mr 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 379 |
| 23 | Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells | Journal of Biological Chemistry | 2008 | 378 |
| 24 | Non-trauma mortality in elderly women with low bone mineral density | Lancet, The | 1991 | 377 |
| 25 | Inflammation in the course of early myocardial ischemia | FASEB Journal | 1991 | 377 |
| 26 | Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS | Kidney International | 2002 | 376 |
| 27 | The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39. | Journal of Clinical Investigation | 1997 | 369 |
| 28 | Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation | Bone Marrow Transplantation | 2016 | 364 |
| 29 | Effects of Intensive BP Control in CKD | Journal of the American Society of Nephrology: JASN | 2017 | 364 |
| 30 | Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1β production in Helicobacter pylori infection | Gastroenterology | 2002 | 356 |
| 31 | CD44 Interaction with Na+-H+ Exchanger (NHE1) Creates Acidic Microenvironments Leading to Hyaluronidase-2 and Cathepsin B Activation and Breast Tumor Cell Invasion | Journal of Biological Chemistry | 2004 | 356 |
| 32 | Left Ventricular Remodeling in Transgenic Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor | Circulation | 2001 | 353 |
| 33 | Endothelins in the normal and diseased kidney | American Journal of Kidney Diseases | 1997 | 351 |
| 34 | The Electrophysiological Mechanism of Ventricular Arrhythmias in the Long QT Syndrome | Circulation Research | 1996 | 349 |
| 35 | Seroepidemiology ofHelicobacter pylori infection in India | Digestive Diseases and Sciences | 1991 | 346 |
| 36 | Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood | Lancet, The | 2002 | 341 |
| 37 | I. Helicobacter pylori: Its epidemiology and its role in duodenal ulcer disease | Journal of Gastroenterology and Hepatology (Australia) | 1991 | 340 |
| 38 | Quality of life assessment. An independent prognostic variable for survival in lung cancer | Cancer | 1991 | 331 |
| 39 | Molecular and cellular processing of lung surfactant 1 | FASEB Journal | 1994 | 331 |
| 40 | Liver-Specific igf-1 Gene Deletion Leads to Muscle Insulin Insensitivity | Diabetes | 2001 | 329 |
| 41 | Overexpression of HOXA10 in Murine Hematopoietic Cells Perturbs both Myeloid and Lymphoid Differentiation and Leads to Acute Myeloid Leukemia | Molecular and Cellular Biology | 1997 | 320 |
| 42 | Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action | Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms | 2013 | 320 |
| 43 | Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy | American Journal of Kidney Diseases | 2005 | 317 |
| 44 | Assessing Measurement Properties of Two Single-item General Health Measures | Quality of Life Research | 2006 | 313 |
| 45 | Helicobacter pylori infection in the pathogenesis of duodenal ulcer and gastric cancer: A model | Gastroenterology | 1997 | 309 |
| 46 | Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: A p53-independent induction of p21WAF1/CIP1 via C/EBPβ | Nature Medicine | 1997 | 309 |
| 47 | Recovery after Acute Kidney Injury | American Journal of Respiratory and Critical Care Medicine | 2017 | 309 |
| 48 | Colorectal Cancer and Nonsteroidal Anti-inflammatory Drugs | Advances in Pharmacology | 1997 | 307 |
| 49 | Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress–induced caspase-12 activation | Hepatology | 2002 | 306 |
| 50 | Breast conservationversus mastectomy. Is there a difference in psychological adjustment or quality of life in the year after surgery? | Cancer | 1992 | 303 |
