| Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism | Clinical Pharmacology and Therapeutics | 1999 | 279 |
| Endothelial cell responses to hypoxic stress | Clinical and Experimental Pharmacology and Physiology | 1999 | 262 |
| Entry and integration of transplanted hepatocytes in rat liver plates occur by disruption of hepatic sinusoidal endothelium | Hepatology | 1999 | 237 |
| Transcriptional repression of the transforming growth factor-beta type I receptor gene by DNA methylation results in the development of TGF-beta resistance in human gastric cancer | Oncogene | 1999 | 119 |
| TNF-alpha-mediated apoptosis is initiated in caveolae-like domains | Journal of Immunology | 1999 | 104 |
| Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events | American Journal of Physiology - Renal Physiology | 1999 | 83 |
| Suspected hereditary nonpolyposis colorectal cancer: International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) criteria and results of genetic diagnosis | Diseases of the Colon and Rectum | 1999 | 75 |
| Effect of arsenic trioxide on cell cycle arrest in head and neck cancer cell line PCI-1 | Biochemical and Biophysical Research Communications | 1999 | 64 |
| Protein kinase C-theta (PKCtheta) distribution analysis in hematopoietic cells: proliferating T cells exhibit high proportions of PKCtheta in the particulate fraction | Cellular Immunology | 1999 | 55 |
| Neoadjuvant hormonal therapy before radical prostatectomy and risk of prostate specific antigen failure | Journal of Urology | 1999 | 48 |
| DOWNWARD TREND IN PROSTATE CANCER MORTALITY IN QUEBEC AND CANADA | Journal of Urology | 1999 | 45 |
| Up-regulation of human telomerase catalytic subunit during gastric carcinogenesis | | 1999 | 40 |
| P53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints | Oncogene | 1999 | 37 |
| T cell activation stimulates the association of enzymatically active tyrosine-phosphorylated ZAP-70 with the Crk adapter proteins | Journal of Biological Chemistry | 1999 | 35 |
| Truncation of the TGF-beta type II receptor gene results in insensitivity to TGF-beta in human gastric cancer cells | Oncogene | 1999 | 33 |
| 5-fluorouracil pharmacokinetics: causes for variability and strategies for modulation in cancer chemotherapy | Cancer Investigation | 1999 | 33 |
| Antiproliferative effect of a vitamin D3 analog, EB1089, on HL-60 cells by the induction of TGF-beta receptor | Leukemia Research | 1999 | 30 |
| Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA) | International Journal of Cancer | 1999 | 28 |
| Quiescent nasal T/NK cell lymphoma manifested as primary central nervous system lymphoma | American Journal of Hematology | 1999 | 28 |
| Risk factors for ovarian metastasis following curative resection of gastric adenocarcinoma | | 1999 | 25 |
| Rapid induction of p21WAF1 but delayed down-regulation of Cdc25A in the TGF-beta-induced cell cycle arrest of gastric carcinoma cells | British Journal of Cancer | 1999 | 23 |
| Lovastatin-induced inhibition of HL-60 cell proliferation via cell cycle arrest and apoptosis | Anticancer Research | 1999 | 22 |
| Antiandrogen hepatotoxicity in patients with chronic viral hepatitis | European Urology | 1999 | 19 |
| Alteration of signal-transducing molecules and phenotypical characteristics in peripheral blood lymphocytes from gastric carcinoma patients | Pathobiology | 1999 | 16 |
| Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion | American Journal of Physiology - Renal Physiology | 1999 | 15 |
