| # | Title | Journal | Year | Citations |
|---|
| 1 | CHARMM36m: an improved force field for folded and intrinsically disordered proteins | Nature Methods | 2017 | 3,959 |
| 2 | ColabFold: making protein folding accessible to all | Nature Methods | 2022 | 3,242 |
| 3 | Plant Immunity to Insect Herbivores | Annual Review of Plant Biology | 2008 | 1,975 |
| 4 | Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation | PLoS Biology | 2012 | 1,064 |
| 5 | Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function | Journal of Experimental Biology | 2003 | 876 |
| 6 | VITAMIN SYNTHESIS IN PLANTS: Tocopherols and Carotenoids | Annual Review of Plant Biology | 2006 | 733 |
| 7 | Sulfur Assimilation in Photosynthetic Organisms: Molecular Functions and Regulations of Transporters and Assimilatory Enzymes | Annual Review of Plant Biology | 2011 | 720 |
| 8 | Protein flexibility predictions using graph theory | Proteins: Structure, Function and Bioinformatics | 2001 | 670 |
| 9 | Feature-based molecular networking in the GNPS analysis environment | Nature Methods | 2020 | 650 |
| 10 | Improved fuel cell and electrode designs for producing electricity from microbial degradation | Biotechnology and Bioengineering | 2003 | 595 |
| 11 | Vitamin E Is Essential for Seed Longevity and for Preventing Lipid Peroxidation during Germination | Plant Cell | 2004 | 552 |
| 12 | WRINKLED1 encodes an AP2/EREB domain protein involved in the control of storage compound biosynthesis in Arabidopsis | Plant Journal | 2004 | 548 |
| 13 | Why there are two cyclooxygenase isozymes | Journal of Clinical Investigation | 2001 | 527 |
| 14 | Recent advances in the development and application of implicit solvent models in biomolecule simulations | Current Opinion in Structural Biology | 2004 | 521 |
| 15 | A roadmap for interpreting 13 C metabolite labeling patterns from cells | Current Opinion in Biotechnology | 2015 | 513 |
| 16 | Omicron Variant (B.1.1.529): Infectivity, Vaccine Breakthrough, and Antibody Resistance | Journal of Chemical Information and Modeling | 2022 | 507 |
| 17 | Contrapuntal Networks of Gene Expression during Arabidopsis Seed Filling[W] | Plant Cell | 2002 | 498 |
| 18 | Detergents as Tools in Membrane Biochemistry | Journal of Biological Chemistry | 2001 | 483 |
| 19 | Fatty acid carbon is essential for dNTP synthesis in endothelial cells | Nature | 2015 | 466 |
| 20 | Systemic signaling in the wound response | Current Opinion in Plant Biology | 2005 | 462 |
| 21 | LRRK2 in Parkinson's disease: protein domains and functional insights | Trends in Neurosciences | 2006 | 439 |
| 22 | Gene Transfer from Bacteria and Archaea Facilitated Evolution of an Extremophilic Eukaryote | Science | 2013 | 439 |
| 23 | Identification of the Carotenoid Isomerase Provides Insight into Carotenoid Biosynthesis, Prolamellar Body Formation, and Photomorphogenesis | Plant Cell | 2002 | 437 |
| 24 | Freezing Tolerance in Plants Requires Lipid Remodeling at the Outer Chloroplast Membrane | Science | 2010 | 422 |
| 25 | Rare genetic variation at Zea mays crtRB1 increases β-carotene in maize grain | Nature Genetics | 2010 | 421 |
| 26 | Prospects for a bio-based succinate industry | Applied Microbiology and Biotechnology | 2007 | 416 |
| 27 | MCPB.py: A Python Based Metal Center Parameter Builder | Journal of Chemical Information and Modeling | 2016 | 416 |
| 28 | DNA Polymerase γ, The Mitochondrial Replicase | Annual Review of Biochemistry | 2004 | 382 |
| 29 | Three Acyltransferases and Nitrogen-responsive Regulator Are Implicated in Nitrogen Starvation-induced Triacylglycerol Accumulation in Chlamydomonas | Journal of Biological Chemistry | 2012 | 379 |
| 30 | Genome, Functional Gene Annotation, and Nuclear Transformation of the Heterokont Oleaginous Alga Nannochloropsis oceanica CCMP1779 | PLoS Genetics | 2012 | 376 |
| 31 | RNA Interference Silencing of a Major Lipid Droplet Protein Affects Lipid Droplet Size in Chlamydomonas reinhardtii | Eukaryotic Cell | 2010 | 374 |
| 32 | A rapid wound signal activates the systemic synthesis of bioactive jasmonates in Arabidopsis | Plant Journal | 2009 | 370 |
| 33 | DGD1-independent biosynthesis of extraplastidic galactolipids after phosphate deprivation in Arabidopsis | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 346 |
| 34 | Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products* | Journal of Biological Chemistry | 2007 | 341 |
| 35 | Bile Acid Secreted by Male Sea Lamprey That Acts as a Sex Pheromone | Science | 2002 | 333 |
| 36 | Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 331 |
| 37 | Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family | Plant Journal | 2006 | 330 |
| 38 | Rewiring of jasmonate and phytochrome B signalling uncouples plant growth-defense tradeoffs | Nature Communications | 2016 | 323 |
| 39 | From The Cover: Jasmonate-inducible plant enzymes degrade essential amino acids in the herbivore midgut | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 321 |
| 40 | Jasmonate signaling: a conserved mechanism of hormone sensing | Current Opinion in Plant Biology | 2008 | 316 |
| 41 | Arabidopsis disrupted in SQD2 encoding sulfolipid synthase is impaired in phosphate-limited growth | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 306 |
| 42 | Functional analyses of the flowering time geneOsMADS50, the putativeSUPPRESSOR OF OVEREXPRESSION OF CO 1/AGAMOUS-LIKE 20(SOC1/AGL20) ortholog in rice | Plant Journal | 2004 | 300 |
| 43 | TAG, You’re it! Chlamydomonas as a reference organism for understanding algal triacylglycerol accumulation | Current Opinion in Biotechnology | 2012 | 291 |
| 44 | Disruption Mutations of ADA2b and GCN5 Transcriptional Adaptor Genes Dramatically Affect Arabidopsis Growth, Development, and Gene Expression[W] | Plant Cell | 2003 | 288 |
| 45 | Jasmonates as Signals in the Wound Response | Journal of Plant Growth Regulation | 2004 | 287 |
| 46 | Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 282 |
| 47 | Photoperiodic regulation of the C-repeat binding factor (CBF) cold acclimation pathway and freezing tolerance in Arabidopsis thaliana | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 282 |
| 48 | ADP-Glucose Pyrophosphorylase: A Regulatory Enzyme for Plant Starch Synthesis | Photosynthesis Research | 2004 | 279 |
| 49 | Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity | Journal of Lipid Research | 2006 | 279 |
| 50 | The Productive Conformation of Arachidonic Acid Bound to Prostaglandin Synthase | Science | 2000 | 278 |
