| # | Title | Journal | Year | Citations |
|---|
| 1 | Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects | Nature Communications | 2019 | 226 |
| 2 | Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists | Science Signaling | 2020 | 219 |
| 3 | Morphine‐induced respiratory depression is independent of β‐arrestin2 signalling | British Journal of Pharmacology | 2020 | 182 |
| 4 | Comprehensive comparison of three different animal models for systemic inflammation | Journal of Biomedical Science | 2017 | 166 |
| 5 | Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury | Nature Neuroscience | 2020 | 148 |
| 6 | Targeting multiple opioid receptors – improved analgesics with reduced side effects? | British Journal of Pharmacology | 2018 | 131 |
| 7 | Comparison of immunoreactive score, HER2/neu score and H score for the immunohistochemical evaluation of somatostatin receptors in bronchopulmonary neuroendocrine neoplasms | Histopathology | 2015 | 123 |
| 8 | Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke | Nature Neuroscience | 2020 | 123 |
| 9 | Differentiation of Opioid Drug Effects by Hierarchical Multi-Site Phosphorylation | Molecular Pharmacology | 2013 | 113 |
| 10 | Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor | Trends in Pharmacological Sciences | 2020 | 91 |
| 11 | Self-Medication with Over-the-Counter and Prescribed Drugs Causing Adverse-Drug-Reaction-Related Hospital Admissions: Results of a Prospective, Long-Term Multi-Centre Study | Drug Safety | 2014 | 85 |
| 12 | CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons | Development (Cambridge) | 2014 | 68 |
| 13 | Ischemia-Reperfusion Injury in Aged Livers—The Energy Metabolism, Inflammatory Response, and Autophagy | Transplantation | 2018 | 68 |
| 14 | ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not β-Arrestin | Cell Reports | 2019 | 60 |
| 15 | MK2/3 Are Pivotal for IL-33–Induced and Mast Cell–Dependent Leukocyte Recruitment and the Resulting Skin Inflammation | Journal of Immunology | 2016 | 54 |
| 16 | Hierarchical Organization of Multi-Site Phosphorylation at the CXCR4 C Terminus | PLoS ONE | 2013 | 52 |
| 17 | Heterologous regulation of agonist‐independent μ‐opioid receptor phosphorylation by protein kinase C | British Journal of Pharmacology | 2014 | 45 |
| 18 | Loss of Morphine Reward and Dependence in Mice Lacking G Protein–Coupled Receptor Kinase 5 | Biological Psychiatry | 2014 | 45 |
| 19 | Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system | Development (Cambridge) | 2014 | 44 |
| 20 | Different mechanisms of homologous and heterologous μ‐opioid receptor phosphorylation | British Journal of Pharmacology | 2015 | 41 |
| 21 | Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model | Scientific Reports | 2016 | 41 |
| 22 | Stroke induces disease-specific myeloid cells in the brain parenchyma and pia | Nature Communications | 2022 | 40 |
| 23 | Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer’s disease | Acta Neuropathologica | 2015 | 36 |
| 24 | Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists | Science Signaling | 2019 | 36 |
| 25 | Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling | Journal of Neuroscience | 2015 | 35 |
| 26 | Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin | Journal of Cancer Research and Clinical Oncology | 2016 | 33 |
| 27 | Preventable ADRs leading to hospitalization — results of a long-term prospective safety study with 6,427 ADR cases focusing on elderly patients | Expert Opinion on Drug Safety | 2018 | 33 |
| 28 | Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny | Cell Reports | 2020 | 33 |
| 29 | Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects | Oncotarget | 0 | 33 |
| 30 | A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway | Molecular and Cellular Biology | 2012 | 32 |
| 31 | The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors | Journal of Experimental Medicine | 2019 | 32 |
| 32 | CXCR4 prevents dispersion of granule neuron precursors in the adult dentate gyrus | Hippocampus | 2013 | 31 |
| 33 | Cell-Autonomous Regulation of Mu-Opioid Receptor Recycling by Substance P | Cell Reports | 2015 | 30 |
| 34 | Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies | Scientific Reports | 2020 | 29 |
| 35 | Modulation of μ-opioid receptor desensitization in peripheral sensory neurons by phosphoinositide 3-kinase γ | Neuroscience | 2010 | 28 |
| 36 | Emerging Paradigms of G Protein-Coupled Receptor Dephosphorylation | Trends in Pharmacological Sciences | 2017 | 27 |
| 37 | Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets | BMC Cancer | 2017 | 26 |
| 38 | Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice | Nature Communications | 2021 | 25 |
| 39 | Evaluation of somatostatin, CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas | Oncotarget | 2017 | 25 |
| 40 | Reevaluation of sst1 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-7 | Regulatory Peptides | 2013 | 24 |
| 41 | Primary‐like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures | Cell Biology International | 2016 | 24 |
| 42 | Targeting Complement C5a Receptor 1 for the Treatment of Immunosuppression in Sepsis | Molecular Therapy | 2021 | 24 |
| 43 | Determination of sites of U50,488H-promoted phosphorylation of the mouse κ opioid receptor (KOPR): disconnect between KOPR phosphorylation and internalization | Biochemical Journal | 2016 | 23 |
| 44 | Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction | International Journal of Molecular Sciences | 2017 | 23 |
| 45 | Expression of the proliferation marker Ki‐67 associates with tumour staging and clinical outcome in differentiated thyroid carcinomas | Clinical Endocrinology | 2012 | 22 |
| 46 | Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo | Journal of Biomedical Science | 2016 | 22 |
| 47 | Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver | Scientific Reports | 2017 | 22 |
| 48 | Proteasome inhibitor bortezomib enhances the effect of standard chemotherapy in small cell lung cancer | Oncotarget | 2017 | 22 |
| 49 | The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication | Nature Communications | 2020 | 21 |
| 50 | PI3Kγ integrates cAMP and Akt signalling of the μ‐opioid receptor | British Journal of Pharmacology | 2014 | 19 |
