| # | Title | Journal | Year | Citations |
|---|
| 1 | Synaptic, transcriptional and chromatin genes disrupted in autism | Nature | 2014 | 2,254 |
| 2 | Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression | Nature Genetics | 2018 | 2,224 |
| 3 | Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism | Cell | 2020 | 1,422 |
| 4 | Genome-wide association analysis identifies 13 new risk loci for schizophrenia | Nature Genetics | 2013 | 1,395 |
| 5 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 6 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 7 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 8 | Mental health in the COVID-19 pandemic | QJM - Monthly Journal of the Association of Physicians | 2020 | 721 |
| 9 | Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder | Nature Neuroscience | 2017 | 691 |
| 10 | Microduplications of 16p11.2 are associated with schizophrenia | Nature Genetics | 2009 | 646 |
| 11 | Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis | Lancet Psychiatry,the | 2017 | 565 |
| 12 | Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group | Molecular Psychiatry | 2018 | 522 |
| 13 | The genetic architecture of the human cerebral cortex | Science | 2020 | 450 |
| 14 | Meta‐analysis of structural MRI studies in children and adults with attention deficit hyperactivity disorder indicates treatment effects | Acta Psychiatrica Scandinavica | 2012 | 436 |
| 15 | Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children | Molecular Psychiatry | 1999 | 374 |
| 16 | De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability | Molecular Psychiatry | 2014 | 332 |
| 17 | Updated European Consensus Statement on diagnosis and treatment of adult ADHD | European Psychiatry | 2019 | 330 |
| 18 | Evidence for a Susceptibility Gene for Autism on Chromosome 2 and for Genetic Heterogeneity | American Journal of Human Genetics | 2001 | 304 |
| 19 | Evaluating historical candidate genes for schizophrenia | Molecular Psychiatry | 2015 | 281 |
| 20 | Interaction of childhood stress with hippocampus and prefrontal cortex volume reduction in major depression | Journal of Psychiatric Research | 2010 | 275 |
| 21 | The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity | Neuroscience | 2016 | 257 |
| 22 | Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study | Journal of Psychiatry and Neuroscience | 2008 | 211 |
| 23 | Relapse Following Successful Electroconvulsive Therapy for Major Depression: A Meta-Analysis | Neuropsychopharmacology | 2013 | 204 |
| 24 | Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 200 |
| 25 | Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility | Molecular Psychiatry | 2011 | 195 |
| 26 | GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium | Molecular Psychiatry | 2017 | 194 |
| 27 | The Hippocampus in Depression: More Than the Sum of Its Parts? Advanced Hippocampal Substructure Segmentation in Depression | Biological Psychiatry | 2019 | 169 |
| 28 | Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia | American Journal of Medical Genetics Part B: Neuropsychiatric Genetics | 2006 | 162 |
| 29 | Detecting subtle facial emotion recognition deficits in high-functioning Autism using dynamic stimuli of varying intensities | Neuropsychologia | 2010 | 161 |
| 30 | Computational meta‐analysis of statistical parametric maps in major depression | Human Brain Mapping | 2016 | 158 |
| 31 | Supportive text messaging for depression and comorbid alcohol use disorder: single-blind randomised trial | Journal of Affective Disorders | 2012 | 154 |
| 32 | Dementia in people with Down's syndrome | International Journal of Geriatric Psychiatry | 2001 | 149 |
| 33 | Familial patterns and the origins of individual differences in synaesthesia | Cognition | 2008 | 144 |
| 34 | Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex | Brain Imaging and Behavior | 2017 | 144 |
| 35 | Social and monetary reward processing in autism spectrum disorders | Molecular Autism | 2012 | 143 |
| 36 | DNA Methylation of the Serotonin Transporter Gene in Peripheral Cells and Stress-Related Changes in Hippocampal Volume: A Study in Depressed Patients and Healthy Controls | PLoS ONE | 2015 | 140 |
| 37 | Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders | JAMA Psychiatry | 2021 | 136 |
| 38 | The SNP ratio test: pathway analysis of genome-wide association datasets | Bioinformatics | 2009 | 125 |
| 39 | DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic–pituitary–adrenal axis activity and to early life emotional abuse | Psychiatry Research | 2018 | 120 |
| 40 | Attention Network Hypoconnectivity With Default and Affective Network Hyperconnectivity in Adults Diagnosed With Attention-Deficit/Hyperactivity Disorder in Childhood | JAMA Psychiatry | 2013 | 115 |
| 41 | Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attention deficit/hyperactivity disorder | Journal of Child Psychology and Psychiatry and Allied Disciplines | 2009 | 114 |
| 42 | Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD | Molecular Psychiatry | 2005 | 113 |
| 43 | Symptom domains in autism and related conditions: Evidence for familiality | American Journal of Medical Genetics Part A | 2002 | 111 |
| 44 | Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors | Nature Nanotechnology | 2017 | 111 |
| 45 | Auditory Hallucinations and the Brain’s Resting-State Networks: Findings and Methodological Observations | Schizophrenia Bulletin | 2016 | 107 |
| 46 | Self-Alert Training: Volitional modulation of autonomic arousal improves sustained attention | Neuropsychologia | 2008 | 103 |
| 47 | Bitemporal v. high-dose right unilateral electroconvulsive therapy for depression: a systematic review and meta-analysis of randomized controlled trials | Psychological Medicine | 2017 | 101 |
| 48 | Domestic violence against women and the COVID-19 pandemic: What is the role of psychiatry? | International Journal of Law and Psychiatry | 2020 | 98 |
| 49 | A review of gene linkage, association and expression studies in autism and an assessment of convergent evidence | International Journal of Developmental Neuroscience | 2007 | 97 |
| 50 | Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders | Psychiatry Research | 2017 | 96 |
