| # | Title | Journal | Year | Citations |
|---|
| 1 | Synaptic, transcriptional and chromatin genes disrupted in autism | Nature | 2014 | 2,254 |
| 2 | Cerebrospinal fluid and plasma biomarkers in Alzheimer disease | Nature Reviews Neurology | 2010 | 1,598 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism | Cell | 2020 | 1,422 |
| 5 | Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 | Nature | 2018 | 1,115 |
| 6 | Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders | American Journal of Human Genetics | 2014 | 819 |
| 7 | Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder | Nature Neuroscience | 2017 | 691 |
| 8 | Microduplications of 16p11.2 are associated with schizophrenia | Nature Genetics | 2009 | 646 |
| 9 | Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection | PLoS ONE | 2020 | 634 |
| 10 | Transcription factor RORα is critical for nuocyte development | Nature Immunology | 2012 | 530 |
| 11 | Clinical diagnosis and management of amyotrophic lateral sclerosis | Nature Reviews Neurology | 2011 | 503 |
| 12 | Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males | Physiology and Behavior | 2011 | 404 |
| 13 | Regional brain blood flow in man during acute changes in arterial blood gases | Journal of Physiology | 2012 | 396 |
| 14 | Common polygenic variation enhances risk prediction for Alzheimer’s disease | Brain | 2015 | 359 |
| 15 | Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths | Science Immunology | 2021 | 357 |
| 16 | Role of cardiopulmonary exercise testing as a risk-assessment method in patients undergoing intra-abdominal surgery: a systematic review | British Journal of Anaesthesia | 2016 | 343 |
| 17 | Updated European Consensus Statement on diagnosis and treatment of adult ADHD | European Psychiatry | 2019 | 330 |
| 18 | The ability of prehabilitation to influence postoperative outcome after intra-abdominal operation: A systematic review and meta-analysis | Surgery | 2016 | 316 |
| 19 | Strength, Weakness, Opportunity, Threat (SWOT) Analysis of the Adaptations to Anatomical Education in the United Kingdom and Republic of Ireland in Response to the Covid‐19 Pandemic | Anatomical Sciences Education | 2020 | 309 |
| 20 | IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 307 |
| 21 | Guidelines for the diagnosis and treatment of cobalamin and folate disorders | British Journal of Haematology | 2014 | 306 |
| 22 | Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism | Nature Immunology | 2016 | 295 |
| 23 | The prehistoric peopling of Southeast Asia | Science | 2018 | 291 |
| 24 | Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung | Immunity | 2016 | 271 |
| 25 | EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans | Nature Medicine | 2012 | 269 |
| 26 | PD-L1hi B cells are critical regulators of humoral immunity | Nature Communications | 2015 | 261 |
| 27 | The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity | Neuroscience | 2016 | 257 |
| 28 | Using Grounded Theory Method to Capture and Analyze Health Care Experiences | Health Services Research | 2015 | 255 |
| 29 | Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder | Molecular Psychiatry | 2011 | 250 |
| 30 | Maternal Vitamin B12 Status and Risk of Neural Tube Defects in a Population With High Neural Tube Defect Prevalence and No Folic Acid Fortification | Pediatrics | 2009 | 248 |
| 31 | Effects of Folate and Vitamin B12 Deficiencies During Pregnancy on Fetal, Infant, and Child Development | Food and Nutrition Bulletin | 2008 | 245 |
| 32 | Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication | Journal of Immunology | 2016 | 236 |
| 33 | Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery | Breast Cancer Research | 2015 | 231 |
| 34 | The effects of forced exercise on hippocampal plasticity in the rat: A comparison of LTP, spatial- and non-spatial learning | Behavioural Brain Research | 2007 | 230 |
| 35 | Immunity, tolerance and autoimmunity in the liver: A comprehensive review | Journal of Autoimmunity | 2016 | 228 |
| 36 | Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells | Nature Medicine | 2017 | 223 |
| 37 | Nanomedicine applied to translational oncology: A future perspective on cancer treatment | Nanomedicine: Nanotechnology, Biology, and Medicine | 2016 | 220 |
| 38 | Sarcopenia | Annals of Surgery | 2017 | 218 |
| 39 | Anatomy education for the YouTube generation | Anatomical Sciences Education | 2016 | 214 |
| 40 | Persistent endotheliopathy in the pathogenesis of long COVID syndrome | Journal of Thrombosis and Haemostasis | 2021 | 208 |
| 41 | Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner | Biomaterials | 2020 | 207 |
| 42 | Cutting Edge: IL-25 Elicits Innate Lymphoid Type 2 and Type II NKT Cells That Regulate Obesity in Mice | Journal of Immunology | 2013 | 202 |
| 43 | Editorial: low population mortality from COVID‐19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity | Alimentary Pharmacology and Therapeutics | 2020 | 202 |
| 44 | Editor's Choice – European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease | European Journal of Vascular and Endovascular Surgery | 2023 | 190 |
| 45 | Perspective: Vitamin D deficiency and COVID‐19 severity – plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2 and thrombosis | Journal of Internal Medicine | 2021 | 185 |
| 46 | Characterisation of particles in solution – a perspective on light scattering and comparative technologies | Science and Technology of Advanced Materials | 2018 | 180 |
| 47 | SDHB immunohistochemistry: a useful tool in the diagnosis of Carney–Stratakis and Carney triad gastrointestinal stromal tumors | Modern Pathology | 2011 | 179 |
| 48 | Meta-analysis of diffusion tensor imaging studies shows altered fractional anisotropy occurring in distinct brain areas in association with depression | Biology of Mood & Anxiety Disorders | 2011 | 174 |
| 49 | Regulation of inflammation by the antioxidant haem oxygenase 1 | Nature Reviews Immunology | 2021 | 172 |
| 50 | Challenges When Using Grounded Theory | International Journal of Qualitative Methods, The | 2018 | 170 |
