| # | Title | Journal | Year | Citations |
|---|
| 1 | Novel brominated flame retardants: A review of their analysis, environmental fate and behaviour | Environment International | 2011 | 1,188 |
| 2 | Levels and trends of PBDEs and HBCDs in the global environment: Status at the end of 2012 | Environment International | 2014 | 346 |
| 3 | Cytokines as biomarkers of nanoparticle immunotoxicity | Chemical Society Reviews | 2013 | 326 |
| 4 | Design, synthesis and antiinflammatory activity of some 1,3,4-oxadiazole derivatives | European Journal of Medicinal Chemistry | 1996 | 234 |
| 5 | Nanomedicine Fight against Antibacterial Resistance: An Overview of the Recent Pharmaceutical Innovations | Pharmaceutics | 2020 | 188 |
| 6 | Novel 5-(2-hydroxyphenyl)-3-substituted-2,3-dihydro-1,3,4-oxadiazole-2-thione derivatives: Promising anticancer agents | Bioorganic and Medicinal Chemistry | 2006 | 165 |
| 7 | Tetrabromobisphenol-A, hexabromocyclododecane and its degradation products in UK human milk: Relationship to external exposure | Environment International | 2011 | 144 |
| 8 | Synthesis, antitubercular activity and pharmacokinetic studies of some schiff bases derived from 1- alkylisatin and isonicotinic acid hydrazide (inh) | Archives of Pharmacal Research | 2003 | 143 |
| 9 | Nanoparticles as safe and effective delivery systems of antifungal agents: Achievements and challenges | International Journal of Pharmaceutics | 2017 | 134 |
| 10 | Synthesis, theoretical investigations, biocidal screening, DNA binding, in vitro cytotoxicity and molecular docking of novel Cu (II), Pd (II) and Ag (I) complexes of chlorobenzylidene Schiff base: Promising antibiotic and anticancer agents | Applied Organometallic Chemistry | 2018 | 132 |
| 11 | Antisense Oligonucleotides: The State of the Art | Current Medicinal Chemistry | 2005 | 128 |
| 12 | Oral delayed-release system based on Zn-pectinate gel (ZPG) microparticles as an alternative carrier to calcium pectinate beads for colonic drug delivery | International Journal of Pharmaceutics | 2002 | 126 |
| 13 | Antidiabetic activity and toxicity of Zizyphus spina-christi leaves | Journal of Ethnopharmacology | 2005 | 126 |
| 14 | Natural anti-obesity agents | Bulletin of Faculty of Pharmacy, Cairo University | 2014 | 125 |
| 15 | Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors | European Journal of Medicinal Chemistry | 2018 | 122 |
| 16 | Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies | Bioorganic Chemistry | 2018 | 121 |
| 17 | Poly(ethylene oxide)-block-polyphosphester-based paclitaxel conjugates as a platform for ultra-high paclitaxel-loaded multifunctional nanoparticles | Chemical Science | 2013 | 116 |
| 18 | Selective spectrophotometric determination of p-aminophenol and acetaminophen | Talanta | 1997 | 115 |
| 19 | Development and in vitro evaluation of novel floating chitosan microcapsules for oral use: comparison with non-floating chitosan microspheres | International Journal of Pharmaceutics | 2002 | 113 |
| 20 | Anthraquinones, Naphthohydroquinones and Naphthohydroquinone Dimers from Rubia cordifolia and Their Cytotoxic Activity. | Chemical and Pharmaceutical Bulletin | 1993 | 106 |
| 21 | Surface functionalization of polymeric nanoparticles for tumor drug delivery: approaches and challenges | Expert Opinion on Drug Delivery | 2017 | 106 |
| 22 | Improvement of solubility and dissolution rate of indomethacin by solid dispersions in Gelucire 50/13 and PEG4000 | Saudi Pharmaceutical Journal | 2009 | 101 |
| 23 | Clinical translation of nanomedicines: Challenges, opportunities, and keys | Advanced Drug Delivery Reviews | 2022 | 91 |
| 24 | Brominated flame retardants in dust from UK cars – Within-vehicle spatial variability, evidence for degradation and exposure implications | Chemosphere | 2011 | 90 |
| 25 | Nanostructured lipid carriers for improved oral delivery and prolonged antihyperlipidemic effect of simvastatin | Colloids and Surfaces B: Biointerfaces | 2018 | 86 |
| 26 | Analysis of some antifungal drugs by spectrophotometric and spectrofluorimetric methods in different pharmaceutical dosage forms | Journal of Pharmaceutical and Biomedical Analysis | 2000 | 85 |
| 27 | Fluorouracil-Loaded Gold Nanoparticles for the Treatment of Skin Cancer: Development, in Vitro Characterization, and in Vivo Evaluation in a Mouse Skin Cancer Xenograft Model | Molecular Pharmaceutics | 2018 | 85 |
| 28 | Use of charge-transfer complexation in the spectrophotometric analysis of certain cephalosporins | Talanta | 2001 | 84 |
| 29 | Acetophenones, a chalcone, a chromone and flavonoids from Pancratium maritimum | Phytochemistry | 1998 | 80 |
| 30 | Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity | Bioorganic and Medicinal Chemistry | 2007 | 78 |
| 31 | Development and characterization of thermosensitive pluronic-based metronidazole in situ gelling formulations for vaginal application | Acta Pharmaceutica | 2012 | 78 |
| 32 | Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity | European Journal of Medicinal Chemistry | 2009 | 77 |
| 33 | Antibacterial effect of various shapes of silver nanoparticles monitored by SERS | Talanta | 2015 | 76 |
| 34 | Liposomal and Ethosomal Gels for the Topical Delivery of Anthralin: Preparation, Comparative Evaluation and Clinical Assessment in Psoriatic Patients | Pharmaceutics | 2020 | 76 |
| 35 | Spectrofluorometric determination of certain quinolone antibacterials using metal chelation | Talanta | 2003 | 75 |
| 36 | Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes | Bioorganic and Medicinal Chemistry | 2020 | 75 |
| 37 | The enigma of health literacy and COVID-19 pandemic | Public Health | 2020 | 74 |
| 38 | Studies on Balanites aegyptiaca Fruits, an Antidiabetic Egyptian Folk Medicine | Chemical and Pharmaceutical Bulletin | 1991 | 73 |
| 39 | Spectroscopic Analytical Study for the Charge-Transfer Complexation of Certain Cephalosporins with Chloranilic Acid. | Analytical Sciences | 2003 | 73 |
| 40 | Benzimidazole condensed ring systems: New synthesis and antineoplastic activity of substituted 3,4-dihydro- and 1,2,3,4-tetrahydro-benzo [4,5]imidazo[1,2-a]pyrinnidine derivatives | Archives of Pharmacal Research | 2007 | 73 |
| 41 | Modification of N,S co-doped graphene quantum dots with p-aminothiophenol-functionalized gold nanoparticles for molecular imprint-based voltammetric determination of the antiviral drug sofosbuvir | Mikrochimica Acta | 2019 | 73 |
| 42 | Gold nanoparticles enhance 5-fluorouracil anticancer efficacy against colorectal cancer cells | International Journal of Pharmaceutics | 2016 | 72 |
| 43 | Conjunctival and corneal tolerability assessment of ocular naltrexone niosomes and their ingredients on the hen's egg chorioallantoic membrane and excised bovine cornea models | International Journal of Pharmaceutics | 2012 | 71 |
| 44 | Validated spectrofluorometric methods for determination of amlodipine besylate in tablets | Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | 2008 | 70 |
| 45 | A facile synthesis of 3D NiFe2O4 nanospheres anchored on a novel ionic liquid modified reduced graphene oxide for electrochemical sensing of ledipasvir: Application to human pharmacokinetic study | Biosensors and Bioelectronics | 2018 | 70 |
| 46 | Antibiofilm and antivirulence potential of silver nanoparticles against multidrug-resistant Acinetobacter baumannii | Scientific Reports | 2021 | 70 |
| 47 | Liposomes as an ocular delivery system of fluconazole: in‐vitro studies | Acta Ophthalmologica | 2010 | 69 |
| 48 | A single run, rapid polarity switching method for determination of 30 pharmaceuticals and personal care products in waste water using Q-Exactive Orbitrap high resolution accurate mass spectrometry | Journal of Chromatography A | 2019 | 69 |
| 49 | Globally Approved EGFR Inhibitors: Insights into Their Syntheses, Target Kinases, Biological Activities, Receptor Interactions, and Metabolism | Molecules | 2021 | 69 |
| 50 | Simultaneous voltammetric determination of antihypertensive drugs nifedipine and atenolol utilizing MgO nanoplatelet modified screen-printed electrodes in pharmaceuticals and human fluids | Sensors and Actuators B: Chemical | 2017 | 68 |
