| # | Title | Journal | Year | Citations |
|---|
| 1 | Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor | New England Journal of Medicine | 2001 | 1,926 |
| 2 | Adjuvant Docetaxel or Vinorelbine with or without Trastuzumab for Breast Cancer | New England Journal of Medicine | 2006 | 1,317 |
| 3 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 4 | Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial | Annals of Oncology | 2014 | 1,022 |
| 5 | Risk stratification of patients diagnosed with gastrointestinal stromal tumor | Human Pathology | 2008 | 977 |
| 6 | Prostate Cancer and Supplementation With α-Tocopherol and β-Carotene: Incidence and Mortality in a Controlled Trial | Journal of the National Cancer Institute | 1998 | 862 |
| 7 | 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers | Nature Structural and Molecular Biology | 2010 | 846 |
| 8 | One vs Three Years of Adjuvant Imatinib for Operable Gastrointestinal Stromal Tumor | JAMA - Journal of the American Medical Association | 2012 | 832 |
| 9 | Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): The NORDIC NEC study | Annals of Oncology | 2013 | 792 |
| 10 | Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts | Lancet Oncology, The | 2012 | 790 |
| 11 | Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies | PLoS Medicine | 2010 | 764 |
| 12 | A common coding variant in CASP8 is associated with breast cancer risk | Nature Genetics | 2007 | 591 |
| 13 | Gastrointestinal stromal tumour | Lancet, The | 2013 | 518 |
| 14 | Fluorouracil, Epirubicin, and Cyclophosphamide With Either Docetaxel or Vinorelbine, With or Without Trastuzumab, As Adjuvant Treatments of Breast Cancer: Final Results of the FinHer Trial | Journal of Clinical Oncology | 2009 | 406 |
| 15 | VEGF and angiopoietin signaling in tumor angiogenesis and metastasis | Trends in Molecular Medicine | 2011 | 391 |
| 16 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 17 | Tumor doubling times in metastatic malignant melanoma of the uvea Tumor progression before and after treatment | Ophthalmology | 2000 | 334 |
| 18 | Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells | Nature Communications | 2015 | 334 |
| 19 | Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy | Gastroenterology | 2000 | 322 |
| 20 | Adjuvant Clodronate Treatment Does Not Reduce the Frequency of Skeletal Metastases in Node-Positive Breast Cancer Patients: 5-Year Results of a Randomized Controlled Trial | Journal of Clinical Oncology | 2001 | 318 |
| 21 | Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics | PLoS Genetics | 2008 | 315 |
| 22 | Survival Outcomes in Patients With Previously Untreated BRAF Wild-Type Advanced Melanoma Treated With Nivolumab Therapy | JAMA Oncology | 2019 | 295 |
| 23 | Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human Tumors | American Journal of Pathology | 1998 | 289 |
| 24 | Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer | Nature Genetics | 2017 | 289 |
| 25 | Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study | British Journal of Cancer | 2007 | 287 |
| 26 | A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer | Nature Genetics | 2011 | 279 |
| 27 | Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families | Journal of Clinical Oncology | 2020 | 270 |
| 28 | Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: a randomised phase III study with crossover on progression by the Scandinavian Breast Group | European Journal of Cancer | 1999 | 265 |
| 29 | Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses | Nature Genetics | 2020 | 265 |
| 30 | Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapy | Blood | 2007 | 260 |
| 31 | A High Pretreatment Serum Vascular Endothelial Growth Factor Concentration Is Associated With Poor Outcome in Non-Hodgkin's Lymphoma | Blood | 1997 | 240 |
| 32 | High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer | International Journal of Cancer | 1998 | 232 |
| 33 | Gastrointestinal stromal tumor (GIST) | Annals of Oncology | 2006 | 230 |
| 34 | Gastrointestinal Stromal Tumors With KIT Exon 11 Deletions Are Associated With Poor Prognosis | Gastroenterology | 2006 | 211 |
| 35 | HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review | British Journal of Cancer | 2004 | 197 |
| 36 | KIT and Platelet-Derived Growth Factor Receptor Alpha Tyrosine Kinase Gene Mutations and KIT Amplifications in Human Solid Tumors | Journal of Clinical Oncology | 2005 | 195 |
| 37 | A High Tumor-Associated Macrophage Content Predicts Favorable Outcome in Follicular Lymphoma Patients Treated with Rituximab and Cyclophosphamide-Doxorubicin-Vincristine-Prednisone | Clinical Cancer Research | 2007 | 195 |
| 38 | Boron Neutron Capture Therapy in the Treatment of Locally Recurred Head-and-Neck Cancer: Final Analysis of a Phase I/II Trial | International Journal of Radiation Oncology Biology Physics | 2012 | 192 |
| 39 | Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients | Acta Oncológica | 2004 | 189 |
| 40 | A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer | Nature Genetics | 2018 | 184 |
| 41 | NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer | Nature Genetics | 2008 | 181 |
| 42 | PALB2,CHEK2andATMrare variants and cancer risk: data from COGS | Journal of Medical Genetics | 2016 | 174 |
| 43 | SMAD4 as a Prognostic Marker in Colorectal Cancer | Clinical Cancer Research | 2005 | 172 |
| 44 | Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors | Genes Chromosomes and Cancer | 2010 | 172 |
| 45 | Leukocytes and platelets of patients with cancer contain high levels of vascular endothelial growth factor | Clinical Cancer Research | 1999 | 171 |
| 46 | Amitriptyline in the Treatment of Chemotherapy-Induced Neuropathic Symptoms | Journal of Pain and Symptom Management | 2008 | 168 |
| 47 | A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11 | Human Molecular Genetics | 2012 | 168 |
| 48 | Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics | Breast Cancer Research | 2010 | 167 |
| 49 | Risk for Distant Recurrence of Breast Cancer Detected by Mammography Screening or Other Methods | JAMA - Journal of the American Medical Association | 2004 | 165 |
| 50 | Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: a nationwide population-based study | Clinical Cancer Research | 2003 | 160 |
