| # | Title | Journal | Year | Citations |
|---|
| 1 | Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel | Blood | 2017 | 4,375 |
| 2 | Hypertensive Disorders of Pregnancy | Hypertension | 2018 | 1,200 |
| 3 | Non-motor features of Parkinson disease | Nature Reviews Neuroscience | 2017 | 1,182 |
| 4 | Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans | Nature Microbiology | 2020 | 1,115 |
| 5 | Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study | BMJ, The | 2020 | 809 |
| 6 | Psoriasis | Lancet, The | 2021 | 792 |
| 7 | Preconceptional and maternal obesity: epidemiology and health consequences | Lancet Diabetes and Endocrinology,the | 2016 | 732 |
| 8 | The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice | Pregnancy Hypertension | 2018 | 719 |
| 9 | Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 | JAMA Oncology | 2022 | 719 |
| 10 | Short-term and long-term effects of caesarean section on the health of women and children | Lancet, The | 2018 | 682 |
| 11 | Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial | Nature Medicine | 2018 | 649 |
| 12 | Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement | Environmental Health | 2016 | 610 |
| 13 | The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre‐eclampsia: A pragmatic guide for first‐trimester screening and prevention | International Journal of Gynecology and Obstetrics | 2019 | 550 |
| 14 | Genomic Evolution of Breast Cancer Metastasis and Relapse | Cancer Cell | 2017 | 534 |
| 15 | Ferroptosis: Role of lipid peroxidation, iron and ferritinophagy | Biochimica Et Biophysica Acta - General Subjects | 2017 | 529 |
| 16 | Self-organization of the human embryo in the absence of maternal tissues | Nature Cell Biology | 2016 | 516 |
| 17 | Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2018 | 474 |
| 18 | Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial | Lancet, The | 2017 | 469 |
| 19 | Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial | Lancet Oncology, The | 2015 | 433 |
| 20 | The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system? | Acta Neuropathologica | 2018 | 429 |
| 21 | ERS guidelines on the diagnosis and treatment of chronic cough in adults and children | European Respiratory Journal | 2020 | 426 |
| 22 | Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations | Nature | 2017 | 409 |
| 23 | The expanding role of primary care in cancer control | Lancet Oncology, The | 2015 | 399 |
| 24 | Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events | JAMA - Journal of the American Medical Association | 2019 | 399 |
| 25 | T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4 + T cells | Science | 2016 | 395 |
| 26 | Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study | Lancet Respiratory Medicine,the | 2021 | 394 |
| 27 | European Organisation for Research and Treatment of Cancer consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome – Update 2017 | European Journal of Cancer | 2017 | 363 |
| 28 | Metabolic network failures in Alzheimer's disease: A biochemical road map | Alzheimer's and Dementia | 2017 | 362 |
| 29 | Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations | Cell | 2020 | 353 |
| 30 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 31 | Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators | International Journal of Molecular Sciences | 2019 | 339 |
| 32 | Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study | PLoS Medicine | 2018 | 336 |
| 33 | Hypertension Canada’s 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2020 | 324 |
| 34 | Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial | Lancet Haematology,the | 2016 | 322 |
| 35 | Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia | Nature Medicine | 2016 | 322 |
| 36 | Neurological Manifestations of COVID‐19: A systematic review and current update | Acta Neurologica Scandinavica | 2020 | 317 |
| 37 | A Diet Low in FODMAPs Reduces Symptoms in Patients With Irritable Bowel Syndrome and A Probiotic Restores Bifidobacterium Species: A Randomized Controlled Trial | Gastroenterology | 2017 | 315 |
| 38 | Association Between Use of Sodium-Glucose Cotransporter 2 Inhibitors, Glucagon-like Peptide 1 Agonists, and Dipeptidyl Peptidase 4 Inhibitors With All-Cause Mortality in Patients With Type 2 Diabetes | JAMA - Journal of the American Medical Association | 2018 | 313 |
| 39 | Targeting folate receptor alpha for cancer treatment | Oncotarget | 2016 | 308 |
| 40 | Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2 | The Lancet Child and Adolescent Health | 2021 | 304 |
| 41 | Zinc in Cellular Regulation: The Nature and Significance of “Zinc Signals” | International Journal of Molecular Sciences | 2017 | 282 |
| 42 | Complement — tapping into new sites and effector systems | Nature Reviews Immunology | 2014 | 278 |
| 43 | Validity and reliability of the Bristol Stool Form Scale in healthy adults and patients with diarrhoea‐predominant irritable bowel syndrome | Alimentary Pharmacology and Therapeutics | 2016 | 271 |
| 44 | Mechanisms of Action of Probiotics and the Gastrointestinal Microbiota on Gut Motility and Constipation | Advances in Nutrition | 2017 | 269 |
| 45 | World guidelines for falls prevention and management for older adults: a global initiative | Age and Ageing | 2022 | 263 |
| 46 | Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants | Nature Communications | 2017 | 251 |
| 47 | Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein | Cell Reports | 2016 | 250 |
| 48 | SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes | EClinicalMedicine | 2020 | 250 |
| 49 | British Dietetic Association systematic review and evidence‐based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update) | Journal of Human Nutrition and Dietetics | 2016 | 237 |
| 50 | Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes | Diabetes Care | 2020 | 220 |
