| Minimum Information about a Biosynthetic Gene cluster | Nature Chemical Biology | 2015 | 498 |
| APOBECs and virus restriction | Virology | 2015 | 291 |
| Metabolic functions of FABPs--mechanisms and therapeutic implications | Nature Reviews Endocrinology | 2015 | 288 |
| APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity | Cancer Discovery | 2015 | 267 |
| Randomized Trial of Reduced-Nicotine Standards for Cigarettes | New England Journal of Medicine | 2015 | 237 |
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS | Journal of Medicinal Chemistry | 2015 | 219 |
| DNA2 drives processing and restart of reversed replication forks in human cells | Journal of Cell Biology | 2015 | 214 |
| Structure of the key species in the enzymatic oxidation of methane to methanol | Nature | 2015 | 198 |
| Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch | Developmental Cell | 2015 | 184 |
| Tissue-Specific Distribution of iNKT Cells Impacts Their Cytokine Response | Immunity | 2015 | 167 |
| mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation | Molecular Cell | 2015 | 162 |
| How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes | ACS Catalysis | 2015 | 147 |
| Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration | Cell Reports | 2015 | 106 |
| Role of the Strength of Drug-Polymer Interactions on the Molecular Mobility and Crystallization Inhibition in Ketoconazole Solid Dispersions | Molecular Pharmaceutics | 2015 | 95 |
| Multi-omic data analysis using Galaxy | Nature Biotechnology | 2015 | 93 |
| The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers | Cancer Research | 2015 | 87 |
| Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link | EMBO Journal | 2015 | 81 |
| Catalysis-dependent selenium incorporation and migration in the nitrogenase active site iron-molybdenum cofactor | ELife | 2015 | 81 |
| Product microbial disinfection and biotechnology | Microbial Biotechnology | 2015 | 78 |
| Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain | Journal of Biological Chemistry | 2015 | 71 |
| An ancient protein-DNA interaction underlying metazoan sex determination | Nature Structural and Molecular Biology | 2015 | 70 |
| Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity | Journal of Molecular and Cellular Cardiology | 2015 | 69 |
| Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature | Human Mutation | 2015 | 67 |
| The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization | Structure | 2015 | 65 |
| Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2 | Molecular and Cellular Biology | 2015 | 65 |
