| # | Title | Journal | Year | Citations |
|---|
| 1 | Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors | Gene | 1985 | 16,607 |
| 2 | Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis | Gene | 1983 | 2,690 |
| 3 | A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose | Analytical Biochemistry | 1968 | 1,262 |
| 4 | Dioxygen Activation by Enzymes Containing Binuclear Non-Heme Iron Clusters | Chemical Reviews | 1996 | 1,211 |
| 5 | DNA condensation | Current Opinion in Structural Biology | 1996 | 1,093 |
| 6 | Nitrogenase MoFe-Protein at 1.16 A Resolution: A Central Ligand in the FeMo-Cofactor | Science | 2002 | 1,041 |
| 7 | DNA condensation by multivalent cations | Science | 1997 | 1,019 |
| 8 | Anatomy of protein pockets and cavities: Measurement of binding site geometry and implications for ligand design | Protein Science | 1998 | 949 |
| 9 | Ionic effects on the elasticity of single DNA molecules | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 929 |
| 10 | Electroporation of cell membranes | Biophysical Journal | 1991 | 926 |
| 11 | Structural basis of biological nitrogen fixation | Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences | 2005 | 852 |
| 12 | Nucleation, Rapid Folding, and Globular Intrachain Regions in Proteins | Proceedings of the National Academy of Sciences of the United States of America | 1973 | 761 |
| 13 | Condensation of DNA by multivalent cations: Considerations on mechanism | Biopolymers | 1991 | 689 |
| 14 | Implications of antinutritional components in soybean foods | Critical Reviews in Food Science and Nutrition | 1994 | 652 |
| 15 | Hydrodynamic properties of complex, rigid, biological macromolecules: theory and applications | Quarterly Reviews of Biophysics | 1981 | 612 |
| 16 | An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane Monooxygenase | Science | 1997 | 583 |
| 17 | Preparation of Milk Fat Methyl Esters by Alcoholysis in an Essentially Nonalcoholic Solution | Journal of Dairy Science | 1969 | 548 |
| 18 | Macroion Attraction Due to Electrostatic Correlation between Screening Counterions. 1. Mobile Surface-Adsorbed Ions and Diffuse Ion Cloud | The Journal of Physical Chemistry | 1996 | 522 |
| 19 | Structure of ADP·AIF4–-stabilized nitrogenase complex and its implications for signal transduction | Nature | 1997 | 517 |
| 20 | Myasthenia gravis: past, present, and future | Journal of Clinical Investigation | 2006 | 515 |
| 21 | The Mode of Action of Vitamin K | Journal of Biological Chemistry | 1974 | 478 |
| 22 | Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins | Advances in Protein Chemistry | 1994 | 433 |
| 23 | [17]Gene splicing by overlap extension | Methods in Enzymology | 1993 | 429 |
| 24 | Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus trichosporium OB3b: mechanistic and environmental implications | Biochemistry | 1990 | 420 |
| 25 | Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice | Nature Medicine | 2009 | 404 |
| 26 | Biochemistry of the Soluble Methane Monooxygenase | Annual Review of Microbiology | 1994 | 393 |
| 27 | Proteasomal Turnover of p21Cip1 Does Not Require p21Cip1 Ubiquitination | Molecular Cell | 2000 | 376 |
| 28 | Degradation of trichloroethylene by toluene dioxygenase in whole-cell studies with Pseudomonas putida F1 | Applied and Environmental Microbiology | 1988 | 362 |
| 29 | Raman spectroscopy of DNA-metal complexes. I. Interactions and conformational effects of the divalent cations: Mg, Ca, Sr, Ba, Mn, Co, Ni, Cu, Pd, and Cd | Biophysical Journal | 1993 | 349 |
| 30 | Posttranslational covalent modification of proteins | Science | 1977 | 348 |
| 31 | Hydrogen exchange and the dynamic structure of proteins | Molecular and Cellular Biochemistry | 1982 | 341 |
| 32 | Spinocerebellar ataxia type 5 in a family descended from the grandparents of President Lincoln maps to chromosome 11 | Nature Genetics | 1994 | 334 |
| 33 | The nucleotide sequence of the maize controlling element Activator | Cell | 1984 | 330 |
| 34 | Structure and assembly of protocatechuate 3,4-dioxygenase | Nature | 1988 | 326 |
| 35 | Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments | Nature Biotechnology | 2000 | 322 |
| 36 | Catabolism of Aromatic Compounds by Micro-Organisms | Advances in Microbial Physiology | 1971 | 313 |
| 37 | Locking in stable states of gene expression: transcriptional control during Drosophila development | Current Opinion in Cell Biology | 1995 | 300 |
| 38 | Methane monooxygenase from Methylosinus trichosporium OB3b | Journal of Biological Chemistry | 1989 | 293 |
| 39 | Expression analysis of the ataxin–1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals | Nature Genetics | 1995 | 291 |
| 40 | Glycophorin is linked by band 4.1 protein to the human erythrocyte membrane skeleton | Nature | 1984 | 290 |
| 41 | REGULATION OF THE EXPRESSION OF LIPOGENIC ENZYME GENES BY CARBOHYDRATE | Annual Review of Nutrition | 1997 | 287 |
| 42 | Nitrogenase: standing at the crossroads | Current Opinion in Chemical Biology | 2000 | 287 |
| 43 | Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1 | Nature | 2008 | 287 |
| 44 | A New Basis for Interpreting the Circular Dichroic Spectra of Proteins | Proceedings of the National Academy of Sciences of the United States of America | 1971 | 282 |
| 45 | Three Phase Partitioning: Concentration and Purification of Proteins | Protein Expression and Purification | 1997 | 280 |
| 46 | Physiological properties and functions of intracellular fatty acid-binding proteins | Lipids and Lipid Metabolism | 1998 | 279 |
| 47 | Scheduling of Radiation with Angiogenesis Inhibitors Anginex and Avastin Improves Therapeutic Outcome via Vessel Normalization | Clinical Cancer Research | 2007 | 270 |
| 48 | Crystal structure of the hydroxylase component of methane monooxygenase fromMethylosinus trichosporiumOB3b | Protein Science | 1997 | 265 |
| 49 | Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate† | Biochemistry | 1996 | 261 |
| 50 | Orientation of spin labels attached to cross-bridges in contracting muscle fibres | Nature | 1982 | 259 |
