| Costs associated with delirium in mechanically ventilated patients | Critical Care Medicine | 2004 | 652 |
| A descriptive study of children dying in the pediatric intensive care unit after withdrawal of life-sustaining treatment | Pediatric Critical Care Medicine | 2004 | 527 |
| Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury | Critical Care Medicine | 2004 | 361 |
| Carbon monoxide in biology and medicine | BioEssays | 2004 | 298 |
| Long-term mortality and quality of life after prolonged mechanical ventilation | Critical Care Medicine | 2004 | 294 |
| The dynamics of acute inflammation | Journal of Theoretical Biology | 2004 | 205 |
| Caveolae compartmentalization of heme oxygenase-1 in endothelial cells | FASEB Journal | 2004 | 158 |
| Effects of hyperchloremic acidosis on arterial pressure and circulating inflammatory molecules in experimental sepsis | Chest | 2004 | 154 |
| Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury | American Journal of Respiratory and Critical Care Medicine | 2004 | 152 |
| Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia | Journal of Neurotrauma | 2004 | 146 |
| Lung transplant outcomes: a review of survival, graft function, physiology, health-related quality of life and cost-effectiveness | European Respiratory Journal | 2004 | 124 |
| Antihypertensive medications and differences in muscle mass in older persons: the Health, Aging and Body Composition Study | Journal of the American Geriatrics Society | 2004 | 110 |
| Carbon monoxide inhibits T lymphocyte proliferation via caspase-dependent pathway | Journal of Immunology | 2004 | 98 |
| Improving care of the critically ill: institutional and health-care system approaches | Lancet, The | 2004 | 98 |
| Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs | FASEB Journal | 2004 | 95 |
| Improving medical crisis team performance | Critical Care Medicine | 2004 | 92 |
| Nanoporous SiC: a candidate semi-permeable material for biomedical applications | Biomedical Microdevices | 2004 | 90 |
| Dysregulation of the immune response in severe sepsis | American Journal of the Medical Sciences | 2004 | 89 |
| Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus | Clinical and Experimental Immunology | 2004 | 88 |
| Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers | Journal of Neurotrauma | 2004 | 80 |
| Comparative analysis of algorithms for signal quantitation from oligonucleotide microarrays | Bioinformatics | 2004 | 75 |
| Hypothermia and injury | Current Opinion in Critical Care | 2004 | 50 |
| Quality of death: assessing the importance placed on end-of-life treatment in the intensive-care unit | Medical Care | 2004 | 48 |
| Vascular endothelial growth factor is increased in cerebrospinal fluid after traumatic brain injury in infants and children | Neurosurgery | 2004 | 47 |
| Pharmacoeconomic implications of new therapies in sepsis | Pharmacoeconomics | 2004 | 46 |
