| # | Title | Journal | Year | Citations |
|---|
| 1 | Gene-expression profiles predict survival of patients with lung adenocarcinoma | Nature Medicine | 2002 | 1,788 |
| 2 | Conjoint Analysis Applications in Health—a Checklist: A Report of the ISPOR Good Research Practices for Conjoint Analysis Task Force | Value in Health | 2011 | 1,342 |
| 3 | Inequality in early childhood: risk and protective factors for early child development | Lancet, The | 2011 | 1,237 |
| 4 | Epidemiology of Pediatric Obstructive Sleep Apnea | Proceedings of the American Thoracic Society | 2008 | 1,093 |
| 5 | Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A | Environmental Health Perspectives | 2010 | 1,038 |
| 6 | Disease proteomics | Nature | 2003 | 955 |
| 7 | Discordant Protein and mRNA Expression in Lung Adenocarcinomas | Molecular and Cellular Proteomics | 2002 | 813 |
| 8 | Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting | European Journal of Endocrinology | 2017 | 771 |
| 9 | Isolation of a partial candidate gene for Menkes disease by positional cloning | Nature Genetics | 1993 | 688 |
| 10 | Integrative clinical genomics of metastatic cancer | Nature | 2017 | 685 |
| 11 | Membrane Type I Matrix Metalloproteinase Usurps Tumor Growth Control Imposed by the Three-Dimensional Extracellular Matrix | Cell | 2003 | 612 |
| 12 | The Effect of Weight Loss on the Sensitivity of Blood Pressure to Sodium in Obese Adolescents | New England Journal of Medicine | 1989 | 593 |
| 13 | Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination | Nature Genetics | 2003 | 582 |
| 14 | EGFR, p16, HPV Titer, Bcl-xL and p53, Sex, and Smoking As Indicators of Response to Therapy and Survival in Oropharyngeal Cancer | Journal of Clinical Oncology | 2008 | 559 |
| 15 | A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition | Nature Genetics | 2011 | 556 |
| 16 | Mutations in FOXC2 (MFH-1), a Forkhead Family Transcription Factor, Are Responsible for the Hereditary Lymphedema-Distichiasis Syndrome | American Journal of Human Genetics | 2000 | 549 |
| 17 | Evidence for impaired t cell dna methylation in systemic lupus erythematosus and rheumatoid arthritis | Arthritis and Rheumatism | 1990 | 536 |
| 18 | The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4 | Nature Genetics | 2006 | 535 |
| 19 | Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible | Nature Genetics | 2006 | 510 |
| 20 | American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock | Critical Care Medicine | 2017 | 475 |
| 21 | Epidemiology of Depressive Symptoms in the National Longitudinal Study of Adolescent Health | Journal of the American Academy of Child and Adolescent Psychiatry | 2002 | 451 |
| 22 | Measuring Therapeutic Response in Chronic Graft-versus-Host Disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. Response Criteria Working Group Report | Biology of Blood and Marrow Transplantation | 2006 | 445 |
| 23 | Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007–2013 | Environmental Health Perspectives | 2014 | 439 |
| 24 | Management of Ingested Foreign Bodies in Children | Journal of Pediatric Gastroenterology and Nutrition | 2015 | 426 |
| 25 | Growth rates and life histories in twenty-two small-scale societies | American Journal of Human Biology | 2006 | 404 |
| 26 | Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis | Nature Genetics | 1993 | 394 |
| 27 | Nephrotic Syndrome in the First Year of Life: Two Thirds of Cases Are Caused by Mutations in 4 Genes (NPHS1, NPHS2, WT1, and LAMB2) | Pediatrics | 2007 | 384 |
| 28 | SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 374 |
| 29 | Mitigation of tracheobronchomalacia with 3D-printed personalized medical devices in pediatric patients | Science Translational Medicine | 2015 | 372 |
| 30 | Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin | Nature Genetics | 2005 | 367 |
| 31 | Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis | Oncogene | 2005 | 354 |
| 32 | Mutations in the Cilia Gene ARL13B Lead to the Classical Form of Joubert Syndrome | American Journal of Human Genetics | 2008 | 352 |
| 33 | A biomarker panel for acute graft-versus-host disease | Blood | 2009 | 348 |
| 34 | Parental Report of Health Conditions and Health Care Use Among Children With and Without Autism | JAMA Pediatrics | 2006 | 346 |
| 35 | COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness | Journal of Clinical Investigation | 2011 | 343 |
| 36 | ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death | New England Journal of Medicine | 2013 | 339 |
| 37 | Variability in Anticoagulation Management of Patients on Extracorporeal Membrane Oxygenation | Pediatric Critical Care Medicine | 2013 | 337 |
| 38 | Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth | JAMA - Journal of the American Medical Association | 2015 | 333 |
| 39 | Chemoselection As a Strategy for Organ Preservation in Advanced Oropharynx Cancer: Response and Survival Positively Associated With HPV16 Copy Number | Journal of Clinical Oncology | 2008 | 329 |
| 40 | TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum | Nature Genetics | 2011 | 326 |
| 41 | Podocyte Hypertrophy, “Adaptation,” and “Decompensation” Associated with Glomerular Enlargement and Glomerulosclerosis in the Aging Rat: Prevention by Calorie Restriction | Journal of the American Society of Nephrology: JASN | 2005 | 325 |
| 42 | Twenty-five–year follow-up among survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study | Blood | 2008 | 324 |
| 43 | Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study | Blood | 2007 | 316 |
| 44 | Global chemical effects of the microbiome include new bile-acid conjugations | Nature | 2020 | 316 |
| 45 | Central nervous system control of metabolism | Nature | 2012 | 307 |
| 46 | Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker | Science Translational Medicine | 2015 | 304 |
| 47 | Weight Status in Young Girls and the Onset of Puberty | Pediatrics | 2007 | 303 |
| 48 | Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease? | Nature Reviews Genetics | 2005 | 296 |
| 49 | Measuring Therapeutic Response in Chronic Graft-versus-Host Disease. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2014 Response Criteria Working Group Report | Biology of Blood and Marrow Transplantation | 2015 | 293 |
| 50 | An immune response manifested by the common occurrence of annexins I and II autoantibodies and high circulating levels of IL-6 in lung cancer | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 286 |
